Methods of treating bipolar disorder | Patent Number 11026951
US 11026951 B2Filled DateJul 10, 2019
Priority DateDec 3, 2013
Publication DateOct 31, 2019
Expiration DateDec 2, 2033
Inventor/ApplicantsSharon Mates
Peng LI
Lawrence P. WENNOGLE
Sharon MATES
Robert DAVIS
Peng Li
Kimberly Vanover
Kimberly VANOVER
Robert Davis
Lawrence P. Wennogle
Peng LI
Lawrence P. WENNOGLE
Sharon MATES
Robert DAVIS
Peng Li
Kimberly Vanover
Kimberly VANOVER
Robert Davis
Lawrence P. Wennogle
ExaminesHEYER, DENNIS
Art Unit1628
Technology Center1600
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The disclosure provides the use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals for the treatment of residual symptoms of psychosis or schizophrenia. The disclosure also provides novel long acting injectable formulations of particular substituted heterocycle fused gamma-carboline compounds and use of such long acting injectable formulations for the treatment of residual symptoms of psychosis or schizophrenia.
1. A method for the treatment of bipolar disorder I and/or bipolar II disorder comprising administering to a patient in need thereof an effective amount of a Compound of Formula I: wherein: X is —N(CH3)— and Y is —C(O)—; in free or pharmaceutically acceptable salt form, wherein said Compound is not used in combination with another antipsychotic agent.
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