The present invention relates to novel oxadiazoles of the formula I or an N-oxide and/or their agriculturally useful salts and to their use for controlling phytopathogenic fungi, or to a method for combating phytopathogenic harmful fungi, which process comprises treating the fungi or the materials, plants, the soil or seeds to be protected against fungal attack, with an effective amount of at least one compound of the formula I, or an N-oxide, or an agriculturally acceptable salt thereof; the present invention also relates to mixtures comprising at least one such compound of the formula I and at least one further pesticidally active substance selected from the group consisting of herbicides, safeners, fungicides, insecticides, and plant growth regulators; and to agrochemical compositions comprising at least one such compound of the formula I and to agrochemical compositions further comprising seeds.

EP 276432 A2 relates to 3-phenyl-5-trifluoromethyloxadiazole derivatives and to their use to combat phytopathogenic microorganisms. WO 2013/008162 describes trifluoromethyl-oxadiazole derivatives with HDAC4 inhibitory activity and their medical use, particularly in the treatment of Huntington's disease, muscle atrophy and diabetes/metabolic syndrome.

In many cases, in particular at low application rates, the fungicidal activity of known fungicidal compounds is unsatisfactory. Based on this, it was an objective of the present invention to provide compounds having improved activity and/or a broader activity spectrum against phytopathogenic fungi. This objective is achieved by the oxadiazoles of the formula I and/or their agriculturally useful salts for controlling phytopathogenic fungi.

The compounds according to the invention differ from those described in EP 276432 A2 in the nature of the group —(C═O)—NR²— on ring A and that the group NR²is substituted by C(R⁵R⁶)—C(R³R⁴)—Y—R¹moiety.

The compounds according to the invention differ from those described in WO 2013/008162 in that ring A can not be phenyl.

Accordingly, the present invention relates to the use of compounds of the formula I, or the N-oxides, or the agriculturally acceptable salts thereof, for combating phytopathogenic harmful fungi

[Image Omitted]

wherein:

A is phenyl or thiophene; and wherein the cyclic groups A are unsubstituted or substituted by 1, 2, 3 or 4 identical or different groups R^A; wherein
- R^Ais halogen, cyano, diC₁-C₆-alkylamino, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₁-C₆-alkylthio, C₁-C₆-alkylsulfinyl, C₁-C₆-alkylsulfonyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₈-cycloalkyl or C₃-C₈-cycloalkoxy; and wherein any of the aliphatic or cyclic moieties are unsubstituted or substituted by 1, 2, 3 or 4 identical or different groups R^a; wherein
  - R^ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy;

Y is N, O; and wherein, if Y is N, N is substituted by two identical or different groups R¹;

R¹is hydrogen, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₈-cycloalkyl, C₃-C₈-cycloalkenyl, C(═O)—(C₁-C₆-alkyl), C₁-C₄-alkoxyimino, C₁-C₆-alkoxyimino-C₁-C₄-alkyl, C₂-C₆-alkenyloxyimino-C₁-C₄-alkyl, C₂-C₆-alkynyloxyimino-C₁-C₄-alkyl, C₃-C₆-cycloalkyl-C₁-C₄-alkyl, phenyl-C₁-C₄-alkyl, heteroaryl-C₁-C₄-alkyl, phenyl, naphthyl or a 3- to 10-membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle, wherein the ring member atoms of said mono- or bicyclic heterocycle include besides carbon atoms further 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms and wherein 1 or 2 carbon ring member atoms of the heterocycle may be replaced by 1 or 2 groups independently selected from C(═O) and C(═S); and wherein the heteroaryl group in heteroaryl-C₁-C₄-alkyl is a 5- or 6-membered aromatic heterocycle, wherein the ring member atoms of the heterocyclic ring include besides carbon atoms 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms; and wherein any of the aliphatic or cyclic groups are unsubstituted or substituted by 1, 2, 3 or up to the maximum possible number of identical or different groups R^1a; or

if Y is N, both groups R¹together with the nitrogen atom to which they are bound form a saturated mono- or bicyclic 3- to 10-membered heterocycle, wherein the heterocycle includes beside one N atom and one or more carbon atoms no further heteroatoms or 1, 2 or 3 further heteroatoms independently selected from N, O and S as ring member atoms; and wherein one or two CH₂groups of the heterocycle may be replaced by one or two groups independently selected from the group of C(═O) and C(═S); and wherein the heterocycle is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^1a; wherein

R^1ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy;

R²is hydrogen, C₁-C₆-alkyl, C₁-C₆-alkyl-CN, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₈-cycloalkyl;

R³, R⁴independently of each other are hydrogen, halogen, cyano, C₁-C₆-alkoxy, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-haloalkyl, C₃-C₈-cycloalkyl; or

R³and R⁴together with the carbon atom to which they are bound form a saturated 3- to 7-membered carbocycle ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^3R; wherein
- R^3Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl; or

R³and R⁴together with the carbon atom to which they are bound form together C═O;

R⁵, R⁶independently of each other are hydrogen, halogen, cyano, C₁-C₆-alkoxy, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-haloalkyl, C₃-C₈-cycloalkyl; or

R⁵and R⁶together with the carbon atom to which they are bound form a saturated 3- to 7-membered carbocycle ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^5R; wherein
- R^5Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl; or

R⁵and R⁶together with the carbon atom to which they are bound form together C═O.

Agriculturally acceptable salts of the compounds of the formula I encompass especially the salts of those cations or the acid addition salts of those acids whose cations and anions, respectively, have no adverse effect on the fungicidal action of the compounds I. Suitable cations are thus in particular the ions of the alkali metals, preferably sodium and potassium, of the alkaline earth metals, preferably calcium, magnesium and barium, of the transition metals, preferably manganese, copper, zinc and iron, and also the ammonium ion which, if desired, may carry one to four C₁-C₄-alkyl substituents and/or one phenyl or benzyl substituent, preferably diisopropylammonium, tetramethylammonium, tetrabutylammonium, trimethylbenzylammonium, furthermore phosphonium ions, sulfonium ions, preferably tri(C₁-C₄-alkyl)sulfonium, and sulfoxonium ions, preferably tri(C₁-C₄-alkyl)sulfoxonium.

Anions of acceptable acid addition salts are primarily chloride, bromide, fluoride, hydrogensulfate, sulfate, dihydrogenphosphate, hydrogenphosphate, phosphate, nitrate, bicarbonate, carbonate, hexafluorosilicate, hexafluorophosphate, benzoate, and the anions of C₁-C₄-alkanoic acids, preferably formate, acetate, propionate and butyrate. They can be formed by reacting a compound I with an acid of the corresponding anion, preferably of hydrochloric acid, hydrobromic acid, sulfuric acid, phosphoric acid or nitric acid.

Compounds of the formula I can exist as one or more stereoisomers. The various stereoisomers include enantiomers, diastereomers, atropisomers arising from restricted rotation about a single bond of asymmetric groups and geometric isomers. They also form part of the subject matter of the present invention. One skilled in the art will appreciate that one stereoisomer may be more active and/or may exhibit beneficial effects when enriched relative to the other stereoisomer(s) or when separated from the other stereoisomer(s). Additionally, the skilled artisan knows how to separate, enrich, and/or to selectively prepare said stereoisomers. The compounds of the invention may be present as a mixture of stereoisomers, e.g. a racemate, individual stereoisomers, or as an optically active form.

Compounds of the formula I can be present in different crystal modifications whose biological activity may differ. They also form part of the subject matter of the present invention.

In respect of the variables, the embodiments of the intermediates obtained during preparation of compounds I correspond to the embodiments of the compounds of formula I. The term “compounds I” refers to compounds of formula I.

In the definitions of the variables given above, collective terms are used which are generally representative for the substituents in question. The term “C_n-C_m” indicates the number of carbon atoms possible in each case in the substituent or substituent moiety in question.

The moieties having two ore more possibilities to be attached apply following: The moieties having no brackets in the name are bonded via the last moiety e.g. C₂-C₆-alkenyloxyimino-C₁-C₄-alkyl is bonded via C₁-C₄-alkyl, heteroaryl-C₁-C₄-alkyl is bonded via C₁-C₄-alkyl etc.

The moieties having brackets in the name are bonded via the first moiety e.g. C(═O)—(C₁-C₆-alkyl) is bonded via C═O, etc.

The term “halogen” refers to fluorine, chlorine, bromine and iodine.

The term “C₁-C₆-alkyl” refers to a straight-chained or branched saturated hydrocarbon group having 1 to 6 carbon atoms, for example methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, and 1,1-dimethylethyl.

The term “C₁-C₆-haloalkyl” refers to a straight-chained or branched alkyl group having 1 to 6 carbon atoms (as defined above), wherein some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as mentioned above, for example chloromethyl, bromomethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl, dichlorofluoromethyl, chlorodifluoromethyl, 1-chloroethyl, 1-bromoethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro-2-fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl and pentafluoroethyl, 2-fluoropropyl, 3-fluoropropyl, 2,2-difluoropropyl, 2,3-difluoropropyl, 2-chloropropyl, 3-chloropropyl, 2,3-dichloropropyl, 2-bromopropyl, 3-bromopropyl, 3,3,3-trifluoropropyl, 3,3,3-trichloropropyl, CH₂—C₂F₅, CF₂—C₂F₅, CF(CF₃)₂, 1-(fluoromethyl)-2-fluoroethyl, 1-(chloromethyl)-2-chloroethyl, 1-(bromomethyl)-2-bromoethyl, 4-fluorobutyl, 4-chlorobutyl, 4-bromobutyl or nonafluorobutyl.

The term “C₁-C₆-alkoxy” refers to a straight-chain or branched alkyl group having 1 to 6 carbon atoms (as defined above) which is bonded via an oxygen, at any position in the alkyl group, for example methoxy, ethoxy, n-propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy or 1,1-dimethylethoxy.

The term “C₁-C₆-haloalkoxy” refers to a C₁-C₆-alkoxy group as defined above, wherein some or all of the hydrogen atoms may be replaced by halogen atoms as mentioned above, for example, OCH₂F, OCHF₂, OCF₃, OCH₂Cl, OCHCl₂, OCCl₃, chlorofluoromethoxy, dichlorofluoromethoxy, chlorodifluoromethoxy, 2-fluoroethoxy, 2-chloroethoxy, 2-bromoethoxy, 2-iodoethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2-fluoroethoxy, 2-chloro-2,2-difluoroethoxy, 2,2-dichloro-2-fluoroethoxy, 2,2,2-trichloroethoxy, OC₂F₅, 2-fluoropropoxy, 3-fluoropropoxy, 2,2-difluoropropoxy, 2,3-difluoropropoxy, 2-chloropropoxy, 3-chloropropoxy, 2,3-dichloropropoxy, 2-bromopropoxy, 3-bromopropoxy, 3,3,3-trifluoropropoxy, 3,3,3-trichloropropoxy, OCH₂—C₂F₅, OCF₂—C₂F₅, 1-(CH₂F)-2-fluoroethoxy, 1-(CH₂Cl)-2-chloroethoxy, 1-(CH₂Br)-2-bromo-ethoxy, 4-fluorobutoxy, 4-chlorobutoxy, 4-bromobutoxy or nonafluorobutoxy.

The terms “phenyl-C₁-C₄-alkyl or heteroaryl-C₁-C₄-alkyl” refer to alkyl having 1 to 4 carbon atoms (as defined above), wherein one hydrogen atom of the alkyl radical is replaced by a phenyl or hetereoaryl radical respectively.

The term “C₁-C₄-alkoxy-C₁-C₄-alkyl” refers to alkyl having 1 to 4 carbon atoms (as defined above), wherein one hydrogen atom of the alkyl radical is replaced by a C₁-C₄-alkoxy group (as defined above). Likewise, the term “C₁-C₄-alkylthio-C₁-C₄-alkyl” refers to alkyl having 1 to 4 carbon atoms (as defined above), wherein one hydrogen atom of the alkyl radical is replaced by a C₁-C₄-alkylthio group.

The term “C₁-C₆-alkylsulfinyl” refers to straight-chain or branched alkyl groups having 1 to 6 carbon atoms (as defined above) bonded through a —S(═O)— moiety, at any position in the alkyl group, for example methylsulfinyl and ethylsulfinyl, and the like. Accordingly, the term “C₁-C₆-haloalkylsulfinyl” refers to straight-chain or branched haloalkyl group having 1 to 6 carbon atoms (as defined above), bonded through a —S(═O)— moiety, at any position in the haloalkyl group.

The term “C₁-C₆-alkylsulfonyl” refers to straight-chain or branched alkyl groups having 1 to 6 carbon atoms (as defined above), bonded through a —S(═O)₂— moiety, at any position in the alkyl group, for example methylsulfonyl. Accordingly, the term “C₁-C₆-haloalkylsulfonyl” refers to straight-chain or branched haloalkyl group having 1 to 6 carbon atoms (as defined above), bonded through a —S(═O)₂— moiety, at any position in the haloalkyl group.

The term “hydroxyC₁-C₄-alkyl” refers to alkyl having 1 to 4 carbon atoms, wherein one hydrogen atom of the alkyl radical is replaced by a OH group.

The term “aminoC₁-C₄-alkyl” refers to alkyl having 1 to 4 carbon atoms, wherein one hydrogen atom of the alkyl radical is replaced by a NH₂group.

The term “C₁-C₄-alkylamino-C₁-C₄-alkyl” refers to refers to alkyl having 1 to 4 carbon atoms (as defined above), wherein one hydrogen atom of the alkyl radical is replaced by a C₁-C₄-alkyl-NH— group which is bound through the nitrogen. Likewise the term “diC₁-C₄-alkylamino-C₁-C₄-alkyl” refers to refers to alkyl having 1 to 4 carbon atoms (as defined above), wherein one hydrogen atom of the alkyl radical is replaced by a (C₁-C₄-alkyl)₂N— group which is bound through the nitrogen.

The term “aminocarbonyl-C₁-C₄-alkyl” refers to alkyl having 1 to 4 carbon atoms, wherein one hydrogen atom of the alkyl radical is replaced by a —(C═O)—NH₂group.

The term “C₂-C₆-alkenyl” refers to a straight-chain or branched unsaturated hydrocarbon radical having 2 to 6 carbon atoms and a double bond in any position, such as ethenyl, 1-propenyl, 2-propenyl (allyl), 1-methylethenyl, 1-butenyl, 2-butenyl, 3-butenyl, 1-methyl-1-propenyl, 2-methyl-1-propenyl, 1-methyl-2-propenyl, 2-methyl-2-propenyl.

The term “C₂-C₆-alkynyl” refers to a straight-chain or branched unsaturated hydrocarbon radical having 2 to 6 carbon atoms and containing at least one triple bond, such as ethynyl, 1-propynyl, 2-propynyl (propargyl), 1-butynyl, 2-butynyl, 3-butynyl, 1-methyl-2-propynyl.

The term “C₃-C₈-cycloalkyl” refers to monocyclic saturated hydrocarbon radicals having 3 to 8 carbon ring members such as cyclopropyl (C₃H₅), cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl or cyclooctyl.

The term “C₃-C₈-cycloalkyloxy” refers to a cycloalkyl radical having 3 to 8 carbon atoms (as defined above), which is bonded via an oxygen.

The term “C(═O)—C₁-C₄-alkyl” refers to a radical which is attached through the carbon atom of the C(═O) group as indicated by the number valence of the carbon atom.

The term “aliphatic” refers to compounds or radicals composed of carbon and hydrogen and which are non-aromatic compounds. An alicyclic compound or radical is an organic compound that is both aliphatic and cyclic. They contain one or more all-carbon rings which may be either saturated or unsaturated, but do not have aromatic character.

The terms “cyclic moiety” or “cyclic group” refer to a radical which is an alicyclic ring or an aromatic ring, such as, for example, phenyl or heteroaryl.

The term “and wherein any of the aliphatic or cyclic groups are unsubstituted or substituted by 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^1a” refers to aliphatic groups, cyclic groups and groups, which contain an aliphatic and a cyclic moiety in one group, such as in, for example, phenyl-C₁-C₄-alkyl; therefore a group which contains an aliphatic and a cyclic moiety both of these moieties may be substituted or unsubstituted independently of each other.

The term “heteroaryl” refers to aromatic monocyclic or polycyclic ring systems including besides carbon atoms, 1, 2, 3 or 4 heteroatoms independently selected from the group consisting of N, O and S.

The term “phenyl” refers to an aromatic ring systems including six carbon atoms (commonly referred to as benzene ring). In association with the group A the term “phenyl” is to be interpreted as a benzene ring or phenylene ring, which is attached to both, the oxadiazole moiety and the —C(═O)—N— group.

The term “saturated or partially unsaturated 3-, 4-, 5-, 6- or 7-membered carbocycle” is to be understood as meaning both saturated or partially unsaturated carbocycles having 3, 4, 5, 6 or 7 ring members. Examples include cyclopropyl, cyclopentyl, cyclopentenyl, cyclopentadienyl, cyclohexyl, cyclohexenyl, cyclohexadienyl, cycloheptyl, cycloheptenyl, cycloheptadienyl, and the like.

The term “3- to 10-membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle, wherein the ring member atoms of said mono- or bicyclic heterocycle include besides carbon atoms further 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms”, is to be understood as meaning both, aromatic mono- and bicyclic heteroaromatic ring systems, and also saturated and partially unsaturated heterocycles, for example:

a 3- or 4-membered saturated heterocycle which contains 1 or 2 heteroatoms from the group consisting of N, O and S as ring members such as oxirane, aziridine, thiirane, oxetane, azetidine, thiethane, [1,2]dioxetane, [1,2]dithietane, [1,2]diazetidine;

and a 5- or 6-membered saturated or partially unsaturated heterocycle which contains 1, 2 or 3 heteroatoms from the group consisting of N, O and S as ring members such as 2-tetrahydro-furanyl, 3-tetrahydrofuranyl, 2-tetrahydrothienyl, 3-tetrahydrothienyl, 2-pyrrolidinyl, 3-pyrrolidinyl, 3-isoxazolidinyl, 4-isoxazolidinyl, 5-isoxazolidinyl, 3-isothiazolidinyl, 4-isothiazolidinyl, 5-isothiazolidinyl, 3-pyrazolidinyl, 4-pyrazolidinyl, 5-pyrazolidinyl, 2-oxazolidinyl, 4-oxazolidinyl, 5-oxazolidinyl, 2-thiazolidinyl, 4-thiazolidinyl, 5-thiazolidinyl, 2-imidazolidinyl, 4-imidazolidinyl, 1,2,4-oxadiazolidin-3-yl, 1,2,4-oxadiazolidin-5-yl, 1,2,4-thiadiazolidin-3-yl, 1,2,4-thiadiazolidin-5-yl, 1,2,4-triazolidin-3-yl, 1,3,4-oxadiazolidin-2-yl, 1,3,4-thiadiazolidin-2-yl, 1,3,4-triazolidin-2-yl, 2,3-dihydrofur-2-yl, 2,3-dihydrofur-3-yl, 2,4-dihydrofur-2-yl, 2,4-dihydrofur-3-yl, 2,3-dihydrothien-2-yl, 2,3-dihydrothien-3-yl, 2,4-dihydrothien-2-yl, 2,4-dihydrothien-3-yl, 2-pyrrolin-2-yl, 2-pyrrolin-3-yl, 3-pyrrolin-2-yl, 3-pyrrolin-3-yl, 2-isoxazolin-3-yl, 3-isoxazolin-3-yl, 4-isoxazolin-3-yl, 2-isoxazolin-4-yl, 3-isoxazolin-4-yl, 4-isoxazolin-4-yl, 2-isoxazolin-5-yl, 3-isoxazolin-5-yl, 4-isoxazolin-5-yl, 2-isothiazolin-3-yl, 3-isothiazolin-3-yl, 4-isothiazolin-3-yl, 2-isothiazolin-4-yl, 3-isothiazolin-4-yl, 4-isothiazolin-4-yl, 2-isothiazolin-5-yl, 3-isothiazolin-5-yl, 4-isothiazolin-5-yl, 2,3-dihydropyrazol-1-yl, 2,3-dihydropyrazol-2-yl, 2,3-dihydropyrazol-3-yl, 2,3-dihydropyrazol-4-yl, 2,3-dihydropyrazol-5-yl, 3,4-dihydropyrazol-1-yl, 3,4-dihydropyrazol-3-yl, 3,4-dihydropyrazol-4-yl, 3,4-dihydropyrazol-5-yl, 4,5-dihydropyrazol-1-yl, 4,5-dihydropyrazol-3-yl, 4,5-dihydropyrazol-4-yl, 4,5-dihydropyrazol-5-yl, 2,3-dihydrooxazol-2-yl, 2,3-dihydrooxazol-3-yl, 2,3-dihydrooxazol-4-yl, 2,3-dihydrooxazol-5-yl, 3,4-dihydrooxazol-2-yl, 3,4-dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, 3,4-dihydrooxazol-5-yl, 3,4-dihydrooxazol-2-yl, 3,4-dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, 2-piperidinyl, 3-piperidinyl, 4-piperidinyl, 1,3-dioxan-5-yl, 2-tetrahydropyranyl, 4-tetrahydropyranyl, 2-tetrahydrothienyl, 3-hexahydropyridazinyl, 4-hexahydropyridazinyl, 2-hexahydropyrimidinyl, 4-hexahydropyrimidinyl, 5-hexahydropyrimidinyl, 2-piperazinyl, 1,3,5-hexahydrotriazin-2-yl and 1,2,4-hexahydrotriazin-3-yl and also the corresponding-ylidene radicals; and

a 7-membered saturated or partially unsaturated heterocycle such as tetra- and hexahydroazepinyl, such as 2,3,4,5-tetrahydro[1H]azepin-1-,-2-,-3-,-4-,-5-,-6-or-7-yl, 3,4,5,6-tetrahydro[2H]azepin-2-,-3-,-4-,-5-,-6-or-7-yl, 2,3,4,7-tetrahydro[1H]azepin-1-,-2-,-3-,-4-,-5-,-6-or-7-yl, 2,3,6,7-tetrahydro[1H]azepin-1-,-2-,-3-,-4-,-5-,-6-or-7-yl, hexahydroazepin-1-,-2-,-3-or-4-yl, tetra- and hexahydrooxepinyl such as 2,3,4,5-tetrahydro[1H]oxepin-2-,-3-,-4-,-5-,-6-or-7-yl, 2,3,4,7-tetrahydro[1H]oxepin-2-,-3-,-4-,-5-,-6-or-7-yl, 2,3,6,7-tetrahydro[1H]oxepin-2-,-3-,-4-,-5-,-6-or-7-yl, hexahydroazepin-1-,-2-,-3-or-4-yl, tetra- and hexahydro-1,3-diazepinyl, tetra- and hexahydro-1,4-diazepinyl, tetra- and hexahydro-1,3-oxazepinyl, tetra- and hexahydro-1,4-oxazepinyl, tetra- and hexahydro-1,3-dioxepinyl, tetra- and hexahydro-1,4-dioxepinyl and the corresponding -ylidene radicals; and the term “5- or 6-membered heteroaryl” or the term “5- or 6-membered aromatic heterocycle” refer to aromatic ring systems including besides carbon atoms, 1, 2, 3 or 4 heteroatoms independently selected from the group consisting of N, O and S, for example, a 5-membered heteroaryl such as pyrrol-1-yl, pyrrol-2-yl, pyrrol-3-yl, thien-2-yl, thien-3-yl, furan-2-yl, furan-3-yl, pyrazol-1-yl, pyrazol-3-yl, pyrazol-4-yl, pyrazol-5-yl, imidazol-1-yl, imidazol-2-yl, imidazol-4-yl, imidazol-5-yl, oxazol-2-yl, oxazol-4-yl, oxazol-5-yl, isoxazol-3-yl, isoxazol-4-yl, isoxazol-5-yl, thiazol-2-yl, thiazol-4-yl, thiazol-5-yl, isothiazol-3-yl, isothiazol-4-yl, isothiazol-5-yl, 1,2,4-triazolyl-1-yl, 1,2,4-triazol-3-yl 1,2,4-triazol-5-yl, 1,2,4-oxadiazol-3-yl, 1,2,4-oxadiazol-5-yl and 1,2,4-thiadiazol-3-yl, 1,2,4-thiadiazol-5-yl; or a 6-membered heteroaryl, such as pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, pyridazin-3-yl, pyridazin-4-yl, pyrimidin-2-yl, pyrimidin-4-yl, pyrimidin-5-yl, pyrazin-2-yl and 1,3,5-triazin-2-yl and 1,2,4-triazin-3-yl.

In respect of the variables, the embodiments of the intermediates correspond to the embodiments of the compounds I. Preference is given to those compounds I and, where applicable, also to compounds of all sub-formulae provided herein, wherein all have independently of each other or more preferably in combination (any possible combination of 2 or more substituents as defined herein) the following meanings:

In one aspect of the invention A is phenyl which is unsubstituted or substituted by 1 or 2 identical or different groups R^Aas defined or preferably defined herein and wherein phenyl is attached to the carboxamide group and the trifluoromethyloxadiazole moiety as follows:

[Image Omitted]

In a further aspect of the invention A is phenyl which is unsubstituted and wherein phenyl is attached to the carboxamide group and the trifluoromethyloxadiazole moiety as follows:

[Image Omitted]

In a further aspect of the invention A is phenyl which is unsubstituted and wherein phenyl is attached to the carboxamide group and the trifluoromethyloxadiazole moiety as follows:

[Image Omitted]

In one aspect of the invention A is thiophene which is unsubstituted or substituted by 1 or 2 identical or different groups R^Aas defined or preferably defined herein and wherein thiophene is attached to the carboxamide group and the trifluoromethyloxadiazole moiety as follows:

[Image Omitted]

In a further aspect of the invention A is thiophene which is unsubstituted and wherein thiophene is attached to the carboxamide group and the trifluoromethyloxadiazole moiety as follows:

[Image Omitted]

In a further aspect of the invention A is thiophene which is unsubstituted and wherein thiophene is attached to the g carboxamide group and the trifluoromethyloxadiazole moiety as follows:

[Image Omitted]

In a preferred embodiment of the invention R^Ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl or C₃-C₈-cycloalkyl; and wherein any of the aliphatic and cyclic moieties are unsubstituted or substituted by 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^aas defined or preferably defined herein.

In another preferred embodiment of the invention R^Ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl or C₃-C₈-cycloalkyl; and wherein any of the aliphatic and cyclic moieties are unsubstituted or substituted by 1, 2, 3, 4 or up to the maximum possible number of identical or different groups selected from halogen, cyano, C₁-C₆-alkyl, C₁-C₆-alkoxy and C₃-C₈-cycloalkyl; in particular fluorine.

More preferably R^Ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy or C₁-C₆-haloalkoxy; in particular halogen, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy or C₁-C₆-haloalkoxy; more particularly chlorine, fluorine, methyl, methoxy, trifluoromethyl, trifluoromethoxy, difluoromethyl or difluoromethoxy. In a more preferable embodiment R^Ais chlorine, fluorine or methyl.

R^aaccording to the invention is halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy. In a preferred embodiment of the invention R^ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-alkoxy or C₃-C₈-cycloalkyl. More preferably R^ais halogen, in particular fluorine.

According to one embodiment Y is O, which is substituted by one group R¹. According to one embodiment Y is O and R¹is H. According to another embodiment Y is O and R¹is C₁-C₆-alkyl, preferrerably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl.

According to a further embodiment Y is O and R¹is C₁-C₆-alkoxy-C₁-C₆-alkyl; preferrably with methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy substited methyl, ethyl, n-propyl, in particular substituted methyl. According to a further embodiment Y is O and R¹is C₁-C₆-alkoxy; preferrably methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy. According to a further embodiment Y is O and R¹is C₂-C₆-alkenyl, preferably ethylene. According to a further embodiment Y is O and R¹is C₂-C₆-alkynyl, preferred ethynyl, 1-propynyl. According to a further embodiment Y is O and R¹is C₃-C₈-cycloalkyl, preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl, cyclopentyl or cyclohexyl.

According to one embodiment Y is O and R¹is C₁-C₆-alkyl substituted by halogen, preferrerably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. In a special embodiment of the invention, R¹CF₃.

According to one embodiment Y is O and R¹is C(═O)—(C₁-C₆-alkyl), wherein alkyl is preferrerably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl.

According to one embodiment Y is O and R¹is C₃-C₆-cycloalkyl-C₁-C₄-alkyl, wherein alkyl is preferrerably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl and wherein cycloalkyl is preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl or cyclobutyl. According to one embodiment Y is O and R¹is phenyl-C₁-C₄-alkyl, wherein alkyl is preferrerably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. According to one embodiment Y is O and R¹is heteroaryl-C₁-C₄-alkyl, wherein alkyl is preferrerably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl and wherein heteroaryl is furan, thiophen, pyrazol, isoxazol, imidazole, oxazol, thiazol, triazol, oxydiazol, pyrol, pyriminin.

According to one embodiment Y is O and R¹is phenyl. According to a further embodiment Y is O and R¹is benzyl. According to a further embodiment Y is O and R¹is naphthyl. According to one embodiment Y is O and R¹is a 3- to 10-membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle, wherein the ring member atoms of said mono- or bicyclic heterocycle include besides carbon atoms further 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms and wherein 1 or 2 carbon ring member atoms of the heterocycle may be replaced by 1 or 2 groups independently selected from C(═O) and C(═S); and wherein the heteroaryl group in heteroaryl-C₁-C₄-alkyl is a 5- or 6-membered aromatic heterocycle, wherein the ring member atoms of the heterocyclic ring include besides carbon atoms 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms especially, furan, thiophen, pyrazol, isoxazol, imidazole, oxazol, thiazol, triazol, oxydiazol, pyrol, pyriminin.

In a special embodiment of the invention Y is O and R¹is phenyl. In a further special embodiment of the invention Y is O and R¹is phenyl substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is O and R¹is benzyl substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment Y is O and R¹is naphtyl substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is O and R¹is thiophene substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is O and R¹is pyrol substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is O and R¹is pyrazol substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is O and R¹is pyrimidin substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is O and R¹is oxadiazol substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃.

According to one embodiment Y is N, which is substituted by two identical or different groups R¹. If the two groups R¹are different, they may be differentiated as R¹¹and R¹². According to one embodiment R¹²is hydrogen or methyl and R¹¹is hydrogen or C₁-C₆-alkyl, preferably hydrogen, methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular hydrogen, methyl or ethyl.

According to a further embodiment R¹²is hydrogen or methyl and R¹¹is C₁-C₆-alkoxy-C₁-C₆-alkyl; preferably methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy substited by methyl, ethyl, n-propyl, in particular substituted hydrogen or methyl. According to a further embodiment R¹²is hydrogen or methyl and R¹¹is C₁-C₆-alkoxy; preferrably methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy. According to a further embodiment R¹²is hydrogen or methyl and R¹¹is C₂-C₆-alkenyl, preferably ethylene. According to a further embodiment R¹²is hydrogen or methyl and R¹¹is C₂-C₆-alkynyl, preferred ethynyl, 1-propynyl. According to a further embodiment R¹²is hydrogen or methyl and R¹²is hydrogen or methyl and R¹¹is C₃-C₈-cycloalkyl, preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl, cyclopentyl or cyclohexyl.

According to one embodiment R¹²is hydrogen or methyl and R¹¹is C₁-C₆-alkyl substituted by halogen, preferrerably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. In a special embodiment of the invention R¹²is hydrogen or methyl and R¹¹is CF₃.

According to one embodiment R¹²is hydrogen or methyl and R¹¹is C(═O)—(C₁-C₆-alkyl), wherein alkyl is preferrerably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl.

According to one embodiment R¹²is hydrogen or methyl and R¹¹is C₃-C₆-cycloalkyl-C₁-C₄-alkyl, wherein alkyl is preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl and wherein cycloalkyl is preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl or cyclobutyl. According to one embodiment R¹²is hydrogen or methyl and R¹¹is phenyl-C₁-C₄-alkyl, wherein alkyl is preferably methylene, ethylene, n-propylene, i-propylene, n-butylene, i-butylene, t-butylene, in particular methylene or ethylene. According to one embodiment R¹²is hydrogen or methyl and R¹¹is heteroaryl-C₁-C₄-alkyl, wherein alkyl is preferably methylene, ethylene, n-propylene, i-propylene, n-butylene, i-butylene, t-butylene, in particular methylene or ethylene and wherein heteroaryl is furan, thiophen, pyrazol, isoxazol, imidazole, oxazol, thiazol, triazol, oxydiazol, pyrol, pyriminin.

According to one embodiment R¹²is hydrogen or methyl and R¹¹is phenyl. According to a further embodiment R¹²is hydrogen or methyl and R¹¹is benzyl. According to a further embodiment R¹²is hydrogen or methyl and R¹¹is naphthyl. According to one embodiment R¹²is hydrogen or methyl and R¹¹is a 3- to 10-membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle, wherein the ring member atoms of said mono- or bicyclic heterocycle include besides carbon atoms further 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms and wherein 1 or 2 carbon ring member atoms of the heterocycle may be replaced by 1 or 2 groups independently selected from C(═O) and C(═S); and wherein the heteroaryl group in heteroaryl-C₁-C₄-alkyl is a 5- or 6-membered aromatic heterocycle, wherein the ring member atoms of the heterocyclic ring include besides carbon atoms 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms especially, furan, thiophen, pyrazol, isoxazol, imidazole, oxazol, thiazol, triazol, oxydiazol, pyrol, pyriminin.

In a special embodiment of the invention Y is N, R¹²is hydrogen or methyl and R¹is phenyl substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is N, R¹²is hydrogen or methyl and R¹is benzyl substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment Y is N, R¹²is hydrogen or methyl and R¹is naphtyl substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is N, R¹²is hydrogen or methyl and R¹is thiophene substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is N, R¹²is hydrogen or methyl and R¹is pyrol substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is N, R¹²is hydrogen or methyl and R¹is pyrazol substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is N, R¹²is hydrogen or methyl and R¹is pyrimidin substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention Y is N, R¹²is hydrogen or methyl and R¹is oxadiazol substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃.

According to a further embodiment the above mentioned groups R¹, if Y is O, or R¹¹, if Y is N, may carry one, two, three or four identical or different substituents selected from the group consisting of methyl, ethyl, propyl, butyl, preferably methyl. According to a further embodiment the above mentioned groups R¹, if Y is O, or R¹¹, if Y is N, may carry one, two, three or four identical or different substituents selected from the group consisting of partially or fully halogenated methyl, ethyl, propyl, butyl, preferably partially or fully halogenated methyl, in particular CF₃. According to a further embodiment the above mentioned groups R¹, if Y is O, or R¹¹, if Y is N, may carry one, two, three or four identical or different substituents selected from the group consisting of methoxy, ethoxy, propoxy, butoxy, preferably methoxy. According to a further embodiment the above mentioned groups R¹, if Y is O, or R¹¹, if Y is N, may carry one, two, three or four identical or different substituents selected from the group consisting of partially or fully halogenated methoxy, ethoxy, propoxy, butoxy, preferably partially or fully halogenated methoxy, in particular OCF₃.

According to one embodiment R¹is H. According to one embodiment R¹is C₁-C₆-alkyl, preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. According to a further embodiment R¹is C₁-C₆-alkoxy-C₁-C₆-alkyl; preferrably with methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy substited methyl, ethyl, n-propyl, in particular substituted methyl. According to a further embodiment R¹is C₁-C₆-alkoxy; preferrably methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy. According to a further embodiment R¹is C₂-C₆-alkenyl, preferably ethylene. According to a further embodiment R¹is C₂-C₆-alkynyl, preferred ethynyl, 1-propynyl. According to a further embodiment R¹is C₃-C₈-cycloalkyl, preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl, cyclopentyl or cyclohexyl.

According to one embodiment R¹is C₁-C₆-alkyl substituted by halogen, preferrerably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. In a special embodiment of the invention, R¹CF₃.

According to one embodiment R¹is C(═O)—(C₁-C₆-alkyl), wherein alkyl is preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl.

According to one embodiment R¹is C₃-C₆-cycloalkyl-C₁-C₄-alkyl, wherein alkyl is preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl and wherein cycloalkyl is preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl or cyclobutyl. According to one embodiment R¹is phenyl-C₁-C₄-alkyl, wherein alkyl is preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. According to one embodiment R¹is heteroaryl-C₁-C₄-alkyl, wherein alkyl is preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl and wherein heteroaryl is furan, thiophen, pyrazol, isoxazol, imidazole, oxazol, thiazol, triazol, oxydiazol, pyrol, pyriminin.

According to one embodiment R¹is phenyl. According to a further embodiment R¹is benzyl. According to a further embodiment R¹is naphthyl. According to one embodiment R¹3- to 10-membered saturated, partially unsaturated or aromatic mono- or bicyclic heterocycle, wherein the ring member atoms of said mono- or bicyclic heterocycle include besides carbon atoms further 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms and wherein 1 or 2 carbon ring member atoms of the heterocycle may be replaced by 1 or 2 groups independently selected from C(═O) and C(═S); and wherein the heteroaryl group in heteroaryl-C₁-C₄-alkyl is a 5- or 6-membered aromatic heterocycle, wherein the ring member atoms of the heterocyclic ring include besides carbon atoms 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms especially, furan, thiophen, pyrazol, isoxazol, imidazole, oxazol, thiazol, triazol, oxydiazol, pyrol, pyriminin.

In a special embodiment of the invention, R¹is phenyl. In a further special embodiment of the invention, R¹is phenyl substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention, R¹is benzyl substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment R¹is naphtyl substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention, R¹is thiophene substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention, R¹is pyrol substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention, R¹is pyrazol substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention, R¹is pyrimidin substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. In a further special embodiment of the invention, R¹is oxydiazol substituted by Cl, F, Br, I, CH₃, OCH₃, CF₃or OCF₃. According to a further embodiment R¹together with the nitrogen or oxygen atom to which it is bound forms a saturated mono- or bicyclic 3- to 10-membered heterocycle, wherein the heterocycle includes beside one N or O atom and one or more carbon atoms 1, 2 or 3 heteroatoms independently selected from N, O and S as ring member atoms; and wherein one or two CH₂groups of the heterocycle may be replaced by one or two groups independently selected from the group of C(═O) and C(═S); and wherein the heterocycle is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^1a; wherein R^1ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy.

In one embodiment of the invention R¹together with the N or O atom to which they is bound form a saturated or partially unsaturated 3- to 6-membered heterocycle, wherein the heterocycle includes beside one nitrogen atom and one or more carbon atoms further heteroatoms selected from N, O and S as ring a member atom.

In one embodiment of the invention R¹together with the N or O atom to which it is bound form a saturated or partially unsaturated 3- to 6-membered heterocycle, wherein the heterocycle includes beside one nitrogen atom and one or more carbon atoms no further heteroatoms.

In one embodiment of the invention R¹together with the N or O atom to which it is bound form a saturated or partially unsaturated 3- to 6-membered heterocycle, wherein one or two CH₂groups of the heterocycle may be replaced by one or two groups independently selected from the group of C(═O) and C(═S).

In one embodiment of the invention both groups R¹together with the nitrogen atom to which they are bound form a saturated or partially unsaturated 3- to 6-membered heterocycle, wherein the heterocycle includes beside one nitrogen atom and one or more carbon atoms further heteroatoms selected from N, O and S as ring a member atom.

In one embodiment of the invention both groups R¹together with the nitrogen atom to which they are bound form a saturated or partially unsaturated 3- to 6-membered heterocycle, wherein one or two CH₂groups of the heterocycle may be replaced by one or two groups independently selected from the group of C(═O) and C(═S).

In one preciall preferred embodiment of the invention R¹together with the N atom to which it is bound form a aziridinyl.

In one preciall preferred embodiment of the invention R¹together with the N atom to which it is bound form a azetidinyl.

In one preciall preferred embodiment of the invention R¹together with the N atom to which it is bound form a 1-pyrrolidinyl.

In one preciall preferred embodiment of the invention R¹together with the N atom to which it is bound form a 1-piperidinyl.

In one preciall preferred embodiment of the invention R¹together with the N atom to which it is bound form a 1-piperazinyl.

In one preciall preferred embodiment of the invention R¹together with the N atom to which it is bound form a 1-methyl-4-piperazinyl.

In one preciall preferred embodiment of the invention R¹together with the N atom to which it is bound form a 4-morpholinyl.

In one embodiment of the invention R^1ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy. In another preferred aspect of the invention R^1ais fluorine, chlorine, cyano, methyl, methoxy, trifluoromethyl, trifluoromethoxy, difluoromethyl or difluoromethoxy. In a more preferred aspect of the invention R^1ais halogen or C₁-C₆-alkyl; particularly fluorine, chlorine or methyl.

According to one embodiment R²is hydrogen, C₁-C₆-alkyl, C₁-C₆-alkyl-CN, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl or C₃-C₈-cycloalkyl.

According to one embodiment R²is hydrogen or C₁-C₆-alkyl.

According to one embodiment R²is H. According to one embodiment R²is C₁-C₆-alkyl, preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. According to one embodiment R²is C₁-C₆-alkyl-CN, preferably by CN substituted methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. According to one embodiment R²is C₁-C₆-haloalkyl, preferably halogenated methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. In a special embodiment of the invention, R²CF₃. According to a further embodiment R²is C₁-C₆-alkoxy; preferrably methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy. According to a further embodiment R²is C₂-C₆-alkenyl, preferably ethylene.

According to a further embodiment R²is C₂-C₆-alkynyl, preferred ethynyl, 1-propynyl. According to a further embodiment R²is C₃-C₈-cycloalkyl, preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl, cyclopentyl or cyclohexyl.

According to one special embodiment R²is hydrogen or CH₃.

In a further embodiment R³, R⁴independently of each other are hydrogen, halogen, cyano, C₁-C₆-alkoxy, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-haloalkyl, C₃-C₈-cycloalkyl.

According to one embodiment R³is H. According to one further embodiment R³is F, Cl or Br, especially F. According to one further embodiment R³is CN. According to a further embodiment R³is C₁-C₆-alkoxy; preferrably methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy. According to a further embodiment R³is C₁-C₆-alkyl, preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. According to a further embodiment R³is C₂-C₆-alkenyl, preferably ethylene. According to a further embodiment R³is C₂-C₆-alkynyl, preferred ethynyl, 1-propynyl. According to one embodiment R³is C₁-C₆-haloalkyl, preferably halogenated methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. In a special embodiment of the invention, R³CF₃. R³is C₃-C₈-cycloalkyl, preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl, cyclopentyl or cyclohexyl.

According to one special embodiment R³is hydrogen, F, CN or CH₃.

According to one embodiment R⁴is H. According to one further embodiment R⁴is F, Cl or Br, especially F. According to one further embodiment R⁴is CN. According to a further embodiment R⁴is C₁-C₆-alkoxy; preferrably methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy. According to a further embodiment R⁴is C₁-C₆-alkyl, preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. According to a further embodiment R⁴is C₂-C₆-alkenyl, preferably ethylene. According to a further embodiment R⁴is C₂-C₆-alkynyl, preferred ethynyl, 1-propynyl. According to one embodiment R⁴is C₁-C₆-haloalkyl, preferably halogenated methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. In a special embodiment of the invention, R⁴CF₃. R⁴is C₃-C₈-cycloalkyl, preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl, cyclopentyl or cyclohexyl.

According to one special embodiment R⁴is hydrogen, F, CN or CH₃.

In a further embodiment R³and R⁴together with the carbon atom to which they are bound form a saturated 3- to 7-membered carbocycle ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^3R; wherein R^3Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl.

In a further embodiment R³and R⁴together with the carbon atom to which they are bound form a cyclopropyl ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^3R; wherein R^3Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl.

In a further embodiment R³and R⁴together with the carbon atom to which they are bound form a cyclobutyl ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^3R; wherein R^3Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl.

In a further embodiment R³and R⁴together with the carbon atom to which they are bound form a butyl ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^3R; wherein R^3Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl.

In a further embodiment R³and R⁴together with the carbon atom to which they are bound form C═O.

In a further embodiment R⁵, R⁶independently of each other are hydrogen, halogen, cyano, C₁-C₆-alkoxy, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-haloalkyl, C₃-C₈-cycloalkyl.

According to one embodiment R⁵is H. According to one further embodiment R⁵is F, Cl or Br, especially F. According to one further embodiment R⁵is CN. According to a further embodiment R⁵is C₁-C₆-alkoxy; preferrably methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy. According to a further embodiment R⁵is C₁-C₆-alkyl, preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. According to a further embodiment R⁵is C₂-C₆-alkenyl, preferably ethylene. According to a further embodiment R⁵is C₂-C₆-alkynyl, preferred ethynyl, 1-propynyl. According to one embodiment R⁵is C₁-C₆-haloalkyl, preferably halogenated methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. In a special embodiment of the invention, R⁵CF₃. R⁵is C₃-C₈-cycloalkyl, preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl, cyclopentyl or cyclohexyl.

According to one special embodiment R⁵is hydrogen, F, CN or CH₃.

According to one embodiment R⁶is H. According to one further embodiment R⁶is F, Cl or Br, especially F. According to one further embodiment R⁴is CN. According to a further embodiment R⁶is C₁-C₆-alkoxy; preferrably methoxy, ethoxy, n-propoxy, i-propoxy, n-butoxy, i-butoxy, t-butoxy. According to a further embodiment R⁶is C₁-C₆-alkyl, preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. According to a further embodiment R⁶is C₂-C₆-alkenyl, preferably ethylene. According to a further embodiment R⁶is C₂-C₆-alkynyl, preferred ethynyl, 1-propynyl. According to one embodiment R⁶is C₁-C₆-haloalkyl, preferably halogenated methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, t-butyl, in particular methyl, ethyl. In a special embodiment of the invention, R⁶CF₃. R⁶is C₃-C₈-cycloalkyl, preferrably cyclopropyl, cyclobutyl, cyclopentyl, in particular cyclopropyl, cyclopentyl or cyclohexyl.

According to one special embodiment R⁶is hydrogen, F, CN or CH₃.

In a further embodiment R⁵and R⁶together with the carbon atom to which they are bound form a saturated 3- to 7-membered carbocycle ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^5R; wherein

R^5Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl.

In a further embodiment R⁵and R⁶together with the carbon atom to which they are bound form a cyclopropyl ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^5R; wherein

R^5Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl.

In a further embodiment R⁵and R⁶together with the carbon atom to which they are bound form a cyclobutyl ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^5R; wherein

R^5Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl.

In a further embodiment R⁵and R⁶together with the carbon atom to which they are bound form a butyl ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^5R; wherein

R^5Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl.

In a further embodiment R⁵and R⁶together with the carbon atom to which they are bound form C═O.

According to one embodiment, the present invention relates to compounds of the formula I.A

[Image Omitted]

or to the use of the compounds of the formula I.A for controlling phytopathogenic fungi. Here, the variables are as defined elsewhere herein for formula I, or as defined as being preferred for formula I.

According to one embodiment, the present invention relates to compounds of the formula I.B

[Image Omitted]

or to the use of the compounds of the formula I.B for controlling phytopathogenic fungi. Here, the variables are as defined elsewhere herein for formula I, or as defined as being preferred for formula I.

According to one embodiment, the present invention relates to compounds of the formula I.C

[Image Omitted]

or to the use of the compounds of the formula I.C for controlling phytopathogenic fungi. Here, the variables are as defined elsewhere herein for formula I, or as defined as being preferred for formula I.

According to one embodiment, the present invention relates to compounds of the formula I.D

[Image Omitted]

or to the use of the compounds of the formula I.D for controlling phytopathogenic fungi. Here, the variables are as defined elsewhere herein for formula I, or as defined as being preferred for formula I.

In one aspect the invention relates to the use of compounds of the formula I, herein referred to as compounds of the formula I.1, wherein:

A is phenyl or thiophene; and wherein the cyclic groups A are unsubstituted or substituted by 1, 2, 3 or 4 identical or different groups R^A; wherein
- R^Ais chlorine, fluorine or methyl;

Y is N, O; and wherein, if Y is N, N is substituted by two identical or different groups R¹;

R¹is hydrogen, C₁-C₆-alkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₈-cycloalkyl, C₃-C₈-cycloalkenyl, C(═O)—(C₁-C₆-alkyl), C₃-C₆-cycloalkyl-C₁-C₄-alkyl, phenyl-C₁-C₄-alkyl, heteroaryl-C₁-C₄-alkyl, phenyl or naphthyl; and wherein the heteroaryl group in heteroaryl-C₁-C₄-alkyl is a 5- or 6-membered aromatic heterocycle, wherein the ring member atoms of the heterocyclic ring include besides carbon atoms 1, 2, 3 or 4 heteroatoms selected from N, O and S as ring member atoms; and wherein any of the aliphatic or cyclic groups are unsubstituted or substituted by 1, 2, 3 or up to the maximum possible number of identical or different groups R^1a; or

if Y is N, both groups R¹together with the nitrogen atom to which they are bound form a saturated mono- or bicyclic 3- to 7-membered heterocycle, wherein the heterocycle includes beside one N atom and one or more carbon atoms no further heteroatom or 1, 2 or 3 further heteroatoms independently selected from N, O and S as ring member atoms; and wherein one or two CH₂groups of the heterocycle may be replaced by one or two groups independently selected from the group of C(═O) and C(═S); and wherein the heterocycle is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^1a; wherein

R^1ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy;

R²is hydrogen, C₁-C₆-alkyl, C₁-C₆-alkyl-CN, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₈-cycloalkyl;

R³, R⁴independently of each other are hydrogen, halogen, cyano, C₁-C₆-alkoxy, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-haloalkyl, C₃-C₈-cycloalkyl; or

R³and R⁴together with the carbon atom to which they are bound form a saturated 3- to 7-membered carbocycle ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^3R; wherein
- R^3Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl; or

R³and R⁴together with the carbon atom to which they are bound form together C═O;

R⁵, R⁶independently of each other are hydrogen, halogen, cyano, C₁-C₆-alkoxy, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-haloalkyl, C₃-C₈-cycloalkyl; or

R⁵and R⁶together with the carbon atom to which they are bound form a saturated 3- to 7-membered carbocycle ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^3R; wherein
- R^5Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl; or

R⁵and R⁶together with the carbon atom to which they are bound form together C═O;

or the N-oxides, or the agriculturally acceptable salts thereof for combating phytopathogenic harmful fungi.

In another aspect the invention relates to the use of compounds of the formula I, herein referred to as compounds of the formula I.2, wherein:

A is phenyl or thiophene; and wherein the cyclic groups A are unsubstituted;

Y is N or O; and wherein, if Y is N, N is substituted by two identical or different groups R¹;

R¹is hydrogen, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₃-C₈-cycloalkyl, C₃-C₈-cycloalkenyl, C(═O)—(C₁-C₆-alkyl), C₃-C₆-cycloalkyl-C₁-C₄-alkyl, phenyl-C₁-C₄-alkyl, heteroaryl-C₁-C₄-alkyl or phenyl; and wherein any of the aliphatic or cyclic groups are unsubstituted or substituted by 1, 2, 3 or up to the maximum possible number of identical or different groups R^1a; or

if Y is N, the groups R¹together with the nitrogen atom to which they are bound form a saturated mono- or bicyclic 3- to 7-membered heterocycle, wherein the heterocycle includes beside one N atom and one or more carbon atoms no further heteroatom or 1, 2 or 3 further heteroatoms independently selected from N, O and S as ring member atoms; and wherein one or two CH₂groups of the heterocycle may be replaced by one or two groups independently selected from the group of C(═O) and C(═S); and wherein the heterocycle is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^1a; wherein

R^1ais halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy;

R²is hydrogen, C₁-C₆-alkyl, C₁-C₆-alkyl-CN, C₁-C₆-haloalkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl or C₃-C₈-cycloalkyl;

R³, R⁴independently of each other are hydrogen, halogen, cyano, C₁-C₆-alkoxy, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-haloalkyl, C₃-C₈-cycloalkyl; or

R³and R⁴together with the carbon atom to which they are bound form together C═O;

R⁵, R⁶independently of each other are hydrogen, halogen, cyano, C₁-C₆-alkoxy, C₁-C₆-alkyl, C₂-C₆-alkenyl, C₂-C₆-alkynyl, C₁-C₆-haloalkyl, C₃-C₈-cycloalkyl; preferably hydrogen, C₁-C₆-alkyl or C₂-C₆-alkenyl; or

R⁵and R⁶together with the carbon atom to which they are bound form a saturated 3- to 7-membered carbocycle ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^5R; wherein
- R^5Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl;
  
  or the N-oxides, or the agriculturally acceptable salts thereof for combating phytopathogenic harmful fungi.

In a further aspect the invention relates to the use of compounds of the formula I.1 or I.2,

wherein

R²is hydrogen or C₁-C₆-alkyl;

R³, R⁴are independently selected from the group consisting of hydrogen, F, CN, methyl or ethyl; or R³and R⁴together with the carbon atom to which they are bound form a cyclopropyl ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^3R; wherein R^3Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl; or R³and R⁴together with the carbon atom to which they are bound form C═O;

R⁵, R⁶are independently selected from the group consisting of hydrogen, F, CN, methyl or ethyl; or R⁵and R⁶together with the carbon atom to which they are bound form a cyclopropyl, cyclobutyl or cyclopentyl ring which is unsubstituted or carries 1, 2, 3, 4 or up to the maximum possible number of identical or different groups R^5R; wherein R^5Ris halogen, cyano, C₁-C₆-alkyl, C₁-C₆-haloalkyl, C₁-C₆-alkoxy, C₁-C₆-haloalkoxy, C₃-C₈-cycloalkyl; or R⁵and R⁶together with the carbon atom to which they are bound form C═O;

or the N-oxides, or the agriculturally acceptable salts thereof for combating phytopathogenic harmful fungi.

In another aspect the invention relates to the use of compounds of the formula I.1 or I.2,

wherein

R²is hydrogen or C₁-C₆-alkyl;

R³, R⁴are independently selected from the group consisting of hydrogen, methyl or ethyl; or

R³and R⁴together with the carbon atom to which they are bound form C═O;

R⁵, R⁶are independently selected from the group consisting of hydrogen, methyl or ethyl; or R⁵and R⁶together with the carbon atom to which they are bound form a cyclopropyl, cyclobutyl or cyclopentyl ring which is unsubstituted; or R⁵and R⁶together with the carbon atom to which they are bound form C═O;

or the N-oxides, or the agriculturally acceptable salts thereof for combating phytopathogenic harmful fungi.

Preference is given to the compounds I used according to the invention and to the compounds according to the invention compiled in Tables 1 to 4 below. With regard to the compounds according to the invention the exception as defined above will be considered. The groups mentioned for a substituent in the tables are furthermore per se, independently of the combination in which they are mentioned, a particularly preferred aspect of the substituent in question.

Table 1

Compounds of the formula I.A, in which R¹, R², R³, R⁴, R⁵, R⁶for a compound corresponds in each case to one row of Table A (I.A.I-1 to I.A.I-2102)

Table 2

Compounds of the formula I.B, in which R¹, R², R³, R⁴, R⁵, R⁶for a compound corresponds in each case to one row of Table A (I.B.I-1 to I.B.I-2102)

Table 3

Compounds of the formula I.C, in which R¹, R², R³, R⁴, R⁵, R⁶for a compound corresponds in each case to one row of Table A (I.C.I-1 to I.C.I-2102)

Table 4

Compounds of the formula I.D, in which R¹, R², R³, R⁴, R⁵, R⁶for a compound corresponds in each case to one row of Table A (I.D.I-1 to I.D.I-2102) Table A:

TABLE A

No
R¹
R²
R³
R⁴
R⁵
R⁶

I-1
H, H
H
H
H
H
H

I-2
H, CH₃
H
H
H
H
H

I-3
H, CH₂CH₃
H
H
H
H
H

I-4
H, CH(CH₃)₂
H
H
H
H
H

I-5
H, C₃H₇
H
H
H
H
H

I-6
H, C(═O)CH₃
H
H
H
H
H

I-7
H, C(═O)CH₂CH₃
H
H
H
H
H

I-8
H, C(═O)C₃H₇
H
H
H
H
H

I-9
H, CH₂CN
H
H
H
H
H

I-10
H, H
CH₃
H
H
H
H

I-11
H, CH₃
CH₃
H
H
H
H

I-12
H, CH₂CH₃
CH₃
H
H
H
H

I-13
H, CH(CH₃)₂
CH₃
H
H
H
H

I-14
H, C₃H₇
CH₃
H
H
H
H

I-15
H, C(═O)CH₃
CH₃
H
H
H
H

I-16
H, C(═O)CH₂CH₃
CH₃
H
H
H
H

I-17
H, C(═O)C₃H₇
CH₃
H
H
H
H

I-18
H, CH₂CN
CH₃
H
H
H
H

I-19
H, H
H
CH₃
H
H
H

I-20
H, CH₃
H
CH₃
H
H
H

I-21
H, CH₂CH₃
H
CH₃
H
H
H

I-22
H, CH(CH₃)₂
H
CH₃
H
H
H

I-23
H, C₃H₇
H
CH₃
H
H
H

I-24
H, C(═O)CH₃
H
CH₃
H
H
H

I-25
H, C(═O)CH₂CH₃
H
CH₃
H
H
H

I-26
H, C(═O)C₃H₇
H
CH₃
H
H
H

I-27
H, CH₂CN
H
CH₃
H
H
H

I-28
H, H
CH₃
CH₃
H
H
H

I-29
H, CH₃
CH₃
CH₃
H
H
H

I-30
H, CH₂CH₃
CH₃
CH₃
H
H
H

I-31
H, CH(CH₃)₂
CH₃
CH₃
H
H
H

I-32
H, C₃H₇
CH₃
CH₃
H
H
H

I-33
H, C(═O)CH₃
CH₃
CH₃
H
H
H

I-34
H, C(═O)CH₂CH₃
CH₃
CH₃
H
H
H

I-35
H, C(═O)C₃H₇
CH₃
CH₃
H
H
H

I-36
H, CH₂CN
CH₃
CH₃
H
H
H

I-37
H, H
H
F
H
H
H

I-38
H, CH₃
H
F
H
H
H

I-39
H, CH₂CH₃
H
F
H
H
H

I-40
H, CH(CH₃)₂
H
F
H
H
H

I-41
H, C₃H₇
H
F
H
H
H

I-42
H, C(═O)CH₃
H
F
H
H
H

I-43
H, C(═O)CH₂CH₃
H
F
H
H
H

I-44
H, C(═O)C₃H₇
H
F
H
H
H

I-45
H, CH₂CN
H
F
H
H
H

I-46
H, H
CH₃
F
H
H
H

I-47
H, CH₃
CH₃
F
H
H
H

I-48
H, CH₂CH₃
CH₃
F
H
H
H

I-49
H, CH(CH₃)₂
CH₃
F
H
H
H

I-50
H, C₃H₇
CH₃
F
H
H
H

I-51
H, C(═O)CH₃
CH₃
F
H
H
H

I-52
H, C(═O)CH₂CH₃
CH₃
F
H
H
H

I-53
H, C(═O)C₃H₇
CH₃
F
H
H
H

I-54
H, CH₂CN
CH₃
F
H
H
H

I-55
H, H
H
CH₃
CH₃
H
H

I-56
H, CH₃
H
CH₃
CH₃
H
H

I-57
H, CH₂CH₃
H
CH₃
CH₃
H
H

I-58
H, CH(CH₃)₂
H
CH₃
CH₃
H
H

I-59
H, C₃H₇
H
CH₃
CH₃
H
H

I-60
H, C(═O)CH₃
H
CH₃
CH₃
H
H

I-61
H, C(═O)CH₂CH₃
H
CH₃
CH₃
H
H

I-62
H, C(═O)C₃H₇
H
CH₃
CH₃
H
H

I-63
H, CH₂CN
H
CH₃
CH₃
H
H

I-64
H, H
CH₃
CH₃
CH₃
H
H

I-65
H, CH₃
CH₃
CH₃
CH₃
H
H

I-66
H, CH₂CH₃
CH₃
CH₃
CH₃
H
H

I-67
H, CH(CH₃)₂
CH₃
CH₃
CH₃
H
H

I-68
H, C₃H₇
CH₃
CH₃
CH₃
H
H

I-69
H, C(═O)CH₃
CH₃
CH₃
CH₃
H
H

I-70
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
H
H

I-71
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
H
H

I-72
H, CH₂CN
CH₃
CH₃
CH₃
H
H

I-73
H, H
H
F
CH₃
H
H

I-74
H, CH₃
H
F
CH₃
H
H

I-75
H, CH₂CH₃
H
F
CH₃
H
H

I-76
H, CH(CH₃)₂
H
F
CH₃
H
H

I-77
H, C₃H₇
H
F
CH₃
H
H

I-78
H, C(═O)CH₃
H
F
CH₃
H
H

I-79
H, C(═O)CH₂CH₃
H
F
CH₃
H
H

I-80
H, C(═O)C₃H₇
H
F
CH₃
H
H

I-81
H, CH₂CN
H
F
CH₃
H
H

I-82
H, H
CH₃
F
CH₃
H
H

I-83
H, CH₃
CH₃
F
CH₃
H
H

I-84
H, CH₂CH₃
CH₃
F
CH₃
H
H

I-85
H, CH(CH₃)₂
CH₃
F
CH₃
H
H

I-86
H, C₃H₇
CH₃
F
CH₃
H
H

I-87
H, C(═O)CH₃
CH₃
F
CH₃
H
H

I-88
H, C(═O)CH₂CH₃
CH₃
F
CH₃
H
H

I-89
H, C(═O)C₃H₇
CH₃
F
CH₃
H
H

I-90
H, CH₂CN
CH₃
F
CH₃
H
H

I-91
H, H
H
F
F
H
H

I-92
H, CH₃
H
F
F
H
H

I-93
H, CH₂CH₃
H
F
F
H
H

I-94
H, CH(CH₃)₂
H
F
F
H
H

I-95
H, C₃H₇
H
F
F
H
H

I-96
H, C(═O)CH₃
H
F
F
H
H

I-97
H, C(═O)CH₂CH₃
H
F
F
H
H

I-98
H, C(═O)C₃H₇
H
F
F
H
H

I-99
H, CH₂CN
H
F
F
H
H

I-100
H, H
CH₃
F
F
H
H

I-101
H, CH₃
CH₃
F
F
H
H

I-102
H, CH₂CH₃
CH₃
F
F
H
H

I-103
H, CH(CH₃)₂
CH₃
F
F
H
H

I-104
H, C₃H₇
CH₃
F
F
H
H

I-105
H, C(═O)CH₃
CH₃
F
F
H
H

I-106
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-107
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-108
H, CH₂CN
CH₃
F
F
H
H

I-109
H, H
H
C═O
H
H

I-110
H, CH₃
H
C═O
H
H

I-111
H, CH₂CH₃
H
C═O
H
H

I-112
H, CH(CH₃)₂
H
C═O
H
H

I-113
H, C₃H₇
H
C═O
H
H

I-114
H, C(═O)CH₃
H
C═O
H
H

I-115
H, C(═O)CH₂CH₃
H
C═O
H
H

I-116
H, C(═O)C₃H₇
H
C═O
H
H

I-117
H, CH₂CN
H
C═O
H
H

I-118
H, H
CH₃
C═O
H
H

I-119
H, CH₃
CH₃
C═O
H
H

I-120
H, CH₂CH₃
CH₃
C═O
H
H

I-121
H, CH(CH₃)₂
CH₃
C═O
H
H

I-122
H, C₃H₇
CH₃
C═O
H
H

I-123
H, C(═O)CH₃
CH₃
C═O
H
H

I-124
H, C(═O)CH₂CH₃
CH₃
C═O
H
H

I-125
H, C(═O)C₃H₇
CH₃
C═O
H
H

I-126
H, CH₂CN
CH₃
C═O
H
H

I-127
H, H
H
H
H
CH₃
H

I-128
H, CH₃
H
H
H
CH₃
H

I-129
H, CH₂CH₃
H
H
H
CH₃
H

I-130
H, CH(CH₃)₂
H
H
H
CH₃
H

I-131
H, C₃H₇
H
H
H
CH₃
H

I-132
H, C(═O)CH₃
H
H
H
CH₃
H

I-133
H, C(═O)CH₂CH₃
H
H
H
CH₃
H

I-134
H, C(═O)C₃H₇
H
H
H
CH₃
H

I-135
H, CH₂CN
H
H
H
CH₃
H

I-136
H, H
CH₃
H
H
CH₃
H

I-137
H, CH₃
CH₃
H
H
CH₃
H

I-138
H, CH₂CH₃
CH₃
H
H
CH₃
H

I-139
H, CH(CH₃)₂
CH₃
H
H
CH₃
H

I-140
H, C₃H₇
CH₃
H
H
CH₃
H

I-141
H, C(═O)CH₃
CH₃
H
H
CH₃
H

I-142
H, C(═O)CH₂CH₃
CH₃
H
H
CH₃
H

I-143
H, C(═O)C₃H₇
CH₃
H
H
CH₃
H

I-144
H, CH₂CN
CH₃
H
H
CH₃
H

I-145
H, H
H
CH₃
H
CH₃
H

I-146
H, CH₃
H
CH₃
H
CH₃
H

I-147
H, CH₂CH₃
H
CH₃
H
CH₃
H

I-148
H, CH(CH₃)₂
H
CH₃
H
CH₃
H

I-149
H, C₃H₇
H
CH₃
H
CH₃
H

I-150
H, C(═O)CH₃
H
CH₃
H
CH₃
H

I-151
H, C(═O)CH₂CH₃
H
CH₃
H
CH₃
H

I-152
H, C(═O)C₃H₇
H
CH₃
H
CH₃
H

I-153
H, CH₂CN
H
CH₃
H
CH₃
H

I-154
H, H
CH₃
CH₃
H
CH₃
H

I-155
H, CH₃
CH₃
CH₃
H
CH₃
H

I-156
H, CH₂CH₃
CH₃
CH₃
H
CH₃
H

I-157
H, CH(CH₃)₂
CH₃
CH₃
H
CH₃
H

I-158
H, C₃H₇
CH₃
CH₃
H
CH₃
H

I-159
H, C(═O)CH₃
CH₃
CH₃
H
CH₃
H

I-160
H, C(═O)CH₂CH₃
CH₃
CH₃
H
CH₃
H

I-161
H, C(═O)C₃H₇
CH₃
CH₃
H
CH₃
H

I-162
H, CH₂CN
CH₃
CH₃
H
CH₃
H

I-163
H, H
H
F
H
CH₃
H

I-164
H, CH₃
H
F
H
CH₃
H

I-165
H, CH₂CH₃
H
F
H
CH₃
H

I-166
H, CH(CH₃)₂
H
F
H
CH₃
H

I-167
H, C₃H₇
H
F
H
CH₃
H

I-168
H, C(═O)CH₃
H
F
H
CH₃
H

I-169
H, C(═O)CH₂CH₃
H
F
H
CH₃
H

I-170
H, C(═O)C₃H₇
H
F
H
CH₃
H

I-171
H, CH₂CN
H
F
H
CH₃
H

I-172
H, H
CH₃
F
H
CH₃
H

I-173
H, CH₃
CH₃
F
H
CH₃
H

I-174
H, CH₂CH₃
CH₃
F
H
CH₃
H

I-175
H, CH(CH₃)₂
CH₃
F
H
CH₃
H

I-176
H, C₃H₇
CH₃
F
H
CH₃
H

I-177
H, C(═O)CH₃
CH₃
F
H
CH₃
H

I-178
H, C(═O)CH₂CH₃
CH₃
F
H
CH₃
H

I-179
H, C(═O)C₃H₇
CH₃
F
H
CH₃
H

I-180
H, CH₂CN
CH₃
F
H
CH₃
H

I-181
H, H
H
CH₃
CH₃
CH₃
H

I-182
H, CH₃
H
CH₃
CH₃
CH₃
H

I-183
H, CH₂CH₃
H
CH₃
CH₃
CH₃
H

I-184
H, CH(CH₃)₂
H
CH₃
CH₃
CH₃
H

I-185
H, C₃H₇
H
CH₃
CH₃
CH₃
H

I-186
H, C(═O)CH₃
H
CH₃
CH₃
CH₃
H

I-187
H, C(═O)CH₂CH₃
H
CH₃
CH₃
CH₃
H

I-188
H, C(═O)C₃H₇
H
CH₃
CH₃
CH₃
H

I-189
H, CH₂CN
H
CH₃
CH₃
CH₃
H

I-190
H, H
CH₃
CH₃
CH₃
CH₃
H

I-191
H, CH₃
CH₃
CH₃
CH₃
CH₃
H

I-192
H, CH₂CH₃
CH₃
CH₃
CH₃
CH₃
H

I-193
H, CH(CH₃)₂
CH₃
CH₃
CH₃
CH₃
H

I-194
H, C₃H₇
CH₃
CH₃
CH₃
CH₃
H

I-195
H, C(═O)CH₃
CH₃
CH₃
CH₃
CH₃
H

I-196
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
CH₃
H

I-197
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
CH₃
H

I-198
H, CH₂CN
CH₃
CH₃
CH₃
CH₃
H

I-199
H, H
H
F
CH₃
CH₃
H

I-200
H, CH₃
H
F
CH₃
CH₃
H

I-201
H, CH₂CH₃
H
F
CH₃
CH₃
H

I-202
H, CH(CH₃)₂
H
F
CH₃
CH₃
H

I-203
H, C₃H₇
H
F
CH₃
CH₃
H

I-204
H, C(═O)CH₃
H
F
CH₃
CH₃
H

I-205
H, C(═O)CH₂CH₃
H
F
CH₃
CH₃
H

I-206
H, C(═O)C₃H₇
H
F
CH₃
CH₃
H

I-207
H, CH₂CN
H
F
CH₃
CH₃
H

I-208
H, H
CH₃
F
CH₃
CH₃
H

I-209
H, CH₃
CH₃
F
CH₃
CH₃
H

I-210
H, CH₂CH₃
CH₃
F
CH₃
CH₃
H

I-211
H, CH(CH₃)₂
CH₃
F
CH₃
CH₃
H

I-212
H, C₃H₇
CH₃
F
CH₃
CH₃
H

I-213
H, C(═O)CH₃
CH₃
F
CH₃
CH₃
H

I-214
H, C(═O)CH₂CH₃
CH₃
F
CH₃
CH₃
H

I-215
H, C(═O)C₃H₇
CH₃
F
CH₃
CH₃
H

I-216
H, CH₂CN
CH₃
F
CH₃
CH₃
H

I-217
H, H
H
F
F
H
H

I-218
H, CH₃
H
F
F
H
H

I-219
H, CH₂CH₃
H
F
F
H
H

I-220
H, CH(CH₃)₂
H
F
F
H
H

I-221
H, C₃H₇
H
F
F
H
H

I-222
H, C(═O)CH₃
H
F
F
H
H

I-223
H, C(═O)CH₂CH₃
H
F
F
H
H

I-224
H, C(═O)C₃H₇
H
F
F
H
H

I-225
H, CH₂CN
H
F
F
H
H

I-226
H, H
CH₃
F
F
H
H

I-227
H, CH₃
CH₃
F
F
H
H

I-228
H, CH₂CH₃
CH₃
F
F
H
H

I-229
H, CH(CH₃)₂
CH₃
F
F
H
H

I-230
H, C₃H₇
CH₃
F
F
H
H

I-231
H, C(═O)CH₃
CH₃
F
F
H
H

I-232
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-233
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-234
H, CH₂CN
CH₃
F
F
H
H

I-235
H, H
H
C═O
CH₃
H

I-236
H, CH₃
H
C═O
CH₃
H

I-237
H, CH₂CH₃
H
C═O
CH₃
H

I-238
H, CH(CH₃)₂
H
C═O
CH₃
H

I-239
H, C₃H₇
H
C═O
CH₃
H

I-240
H, C(═O)CH₃
H
C═O
CH₃
H

I-241
H, C(═O)CH₂CH₃
H
C═O
CH₃
H

I-242
H, C(═O)C₃H₇
H
C═O
CH₃
H

I-243
H, CH₂CN
H
C═O
CH₃
H

I-244
H, H
CH₃
C═O
CH₃
H

I-245
H, CH₃
CH₃
C═O
CH₃
H

I-246
H, CH₂CH₃
CH₃
C═O
CH₃
H

I-247
H, CH(CH₃)₂
CH₃
C═O
CH₃
H

I-248
H, C₃H₇
CH₃
C═O
CH₃
H

I-249
H, C(═O)CH₃
CH₃
C═O
CH₃
H

I-250
H, C(═O)CH₂CH₃
CH₃
C═O
CH₃
H

I-251
H, C(═O)C₃H₇
CH₃
C═O
CH₃
H

I-252
H, CH₂CN
CH₃
C═O
CH₃
H

I-253
H, H
H
H
H
F
H

I-254
H, CH₃
H
H
H
F
H

I-255
H, CH₂CH₃
H
H
H
F
H

I-256
H, CH(CH₃)₂
H
H
H
F
H

I-257
H, C₃H₇
H
H
H
F
H

I-258
H, C(═O)CH₃
H
H
H
F
H

I-259
H, C(═O)CH₂CH₃
H
H
H
F
H

I-260
H, C(═O)C₃H₇
H
H
H
F
H

I-261
H, CH₂CN
H
H
H
F
H

I-262
H, H
CH₃
H
H
F
H

I-263
H, CH₃
CH₃
H
H
F
H

I-264
H, CH₂CH₃
CH₃
H
H
F
H

I-265
H, CH(CH₃)₂
CH₃
H
H
F
H

I-266
H, C₃H₇
CH₃
H
H
F
H

I-267
H, C(═O)CH₃
CH₃
H
H
F
H

I-268
H, C(═O)CH₂CH₃
CH₃
H
H
F
H

I-269
H, C(═O)C₃H₇
CH₃
H
H
F
H

I-270
H, CH₂CN
CH₃
H
H
F
H

I-271
H, H
H
CH₃
H
F
H

I-272
H, CH₃
H
CH₃
H
F
H

I-273
H, CH₂CH₃
H
CH₃
H
F
H

I-274
H, CH(CH₃)₂
H
CH₃
H
F
H

I-275
H, C₃H₇
H
CH₃
H
F
H

I-276
H, C(═O)CH₃
H
CH₃
H
F
H

I-277
H, C(═O)CH₂CH₃
H
CH₃
H
F
H

I-278
H, C(═O)C₃H₇
H
CH₃
H
F
H

I-279
H, CH₂CN
H
CH₃
H
F
H

I-280
H, H
CH₃
CH₃
H
F
H

I-281
H, CH₃
CH₃
CH₃
H
F
H

I-282
H, CH₂CH₃
CH₃
CH₃
H
F
H

I-283
H, CH(CH₃)₂
CH₃
CH₃
H
F
H

I-284
H, C₃H₇
CH₃
CH₃
H
F
H

I-285
H, C(═O)CH₃
CH₃
CH₃
H
F
H

I-286
H, C(═O)CH₂CH₃
CH₃
CH₃
H
F
H

I-287
H, C(═O)C₃H₇
CH₃
CH₃
H
F
H

I-288
H, CH₂CN
CH₃
CH₃
H
F
H

I-289
H, H
H
F
H
F
H

I-290
H, CH₃
H
F
H
F
H

I-291
H, CH₂CH₃
H
F
H
F
H

I-292
H, CH(CH₃)₂
H
F
H
F
H

I-293
H, C₃H₇
H
F
H
F
H

I-294
H, C(═O)CH₃
H
F
H
F
H

I-295
H, C(═O)CH₂CH₃
H
F
H
F
H

I-296
H, C(═O)C₃H₇
H
F
H
F
H

I-297
H, CH₂CN
H
F
H
F
H

I-298
H, H
CH₃
F
H
F
H

I-299
H, CH₃
CH₃
F
H
F
H

I-300
H, CH₂CH₃
CH₃
F
H
F
H

I-301
H, CH(CH₃)₂
CH₃
F
H
F
H

I-302
H, C₃H₇
CH₃
F
H
F
H

I-303
H, C(═O)CH₃
CH₃
F
H
F
H

I-304
H, C(═O)CH₂CH₃
CH₃
F
H
F
H

I-305
H, C(═O)C₃H₇
CH₃
F
H
F
H

I-306
H, CH₂CN
CH₃
F
H
F
H

I-307
H, H
H
CH₃
CH₃
F
H

I-308
H, CH₃
H
CH₃
CH₃
F
H

I-309
H, CH₂CH₃
H
CH₃
CH₃
F
H

I-310
H, CH(CH₃)₂
H
CH₃
CH₃
F
H

I-311
H, C₃H₇
H
CH₃
CH₃
F
H

I-312
H, C(═O)CH₃
H
CH₃
CH₃
F
H

I-313
H, C(═O)CH₂CH₃
H
CH₃
CH₃
F
H

I-314
H, C(═O)C₃H₇
H
CH₃
CH₃
F
H

I-315
H, CH₂CN
H
CH₃
CH₃
F
H

I-316
H, H
CH₃
CH₃
CH₃
F
H

I-317
H, CH₃
CH₃
CH₃
CH₃
F
H

I-318
H, CH₂CH₃
CH₃
CH₃
CH₃
F
H

I-319
H, CH(CH₃)₂
CH₃
CH₃
CH₃
F
H

I-320
H, C₃H₇
CH₃
CH₃
CH₃
F
H

I-321
H, C(═O)CH₃
CH₃
CH₃
CH₃
F
H

I-322
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
H

I-323
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
H

I-324
H, CH₂CN
CH₃
CH₃
CH₃
F
H

I-325
H, H
H
F
CH₃
F
H

I-326
H, CH₃
H
F
CH₃
F
H

I-327
H, CH₂CH₃
H
F
CH₃
F
H

I-328
H, CH(CH₃)₂
H
F
CH₃
F
H

I-329
H, C₃H₇
H
F
CH₃
F
H

I-330
H, C(═O)CH₃
H
F
CH₃
F
H

I-331
H, C(═O)CH₂CH₃
H
F
CH₃
F
H

I-332
H, C(═O)C₃H₇
H
F
CH₃
F
H

I-333
H, CH₂CN
H
F
CH₃
F
H

I-334
H, H
CH₃
F
CH₃
F
H

I-335
H, CH₃
CH₃
F
CH₃
F
H

I-336
H, CH₂CH₃
CH₃
F
CH₃
F
H

I-337
H, CH(CH₃)₂
CH₃
F
CH₃
F
H

I-338
H, C₃H₇
CH₃
F
CH₃
F
H

I-339
H, C(═O)CH₃
CH₃
F
CH₃
F
H

I-340
H, C(═O)CH₂CH₃
CH₃
F
CH₃
F
H

I-341
H, C(═O)C₃H₇
CH₃
F
CH₃
F
H

I-342
H, CH₂CN
CH₃
F
CH₃
F
H

I-343
H, H
H
F
F
H
H

I-344
H, CH₃
H
F
F
H
H

I-345
H, CH₂CH₃
H
F
F
H
H

I-346
H, CH(CH₃)₂
H
F
F
H
H

I-347
H, C₃H₇
H
F
F
H
H

I-348
H, C(═O)CH₃
H
F
F
H
H

I-349
H, C(═O)CH₂CH₃
H
F
F
H
H

I-350
H, C(═O)C₃H₇
H
F
F
H
H

I-351
H, CH₂CN
H
F
F
H
H

I-352
H, H
CH₃
F
F
H
H

I-353
H, CH₃
CH₃
F
F
H
H

I-354
H, CH₂CH₃
CH₃
F
F
H
H

I-355
H, CH(CH₃)₂
CH₃
F
F
H
H

I-356
H, C₃H₇
CH₃
F
F
H
H

I-357
H, C(═O)CH₃
CH₃
F
F
H
H

I-358
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-359
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-360
H, CH₂CN
CH₃
F
F
H
H

I-361
H, H
H
C═O
F
H

I-362
H, CH₃
H
C═O
F
H

I-363
H, CH₂CH₃
H
C═O
F
H

I-364
H, CH(CH₃)₂
H
C═O
F
H

I-365
H, C₃H₇
H
C═O
F
H

I-366
H, C(═O)CH₃
H
C═O
F
H

I-367
H, C(═O)CH₂CH₃
H
C═O
F
H

I-368
H, C(═O)C₃H₇
H
C═O
F
H

I-369
H, CH₂CN
H
C═O
F
H

I-370
H, H
CH₃
C═O
F
H

I-371
H, CH₃
CH₃
C═O
F
H

I-372
H, CH₂CH₃
CH₃
C═O
F
H

I-373
H, CH(CH₃)₂
CH₃
C═O
F
H

I-374
H, C₃H₇
CH₃
C═O
F
H

I-375
H, C(═O)CH₃
CH₃
C═O
F
H

I-376
H, C(═O)CH₂CH₃
CH₃
C═O
F
H

I-377
H, C(═O)C₃H₇
CH₃
C═O
F
H

I-378
H, CH₂CN
CH₃
C═O
F
H

I-379
H, H
H
H
H
CH₃
CH₃

I-380
H, CH₃
H
H
H
CH₃
CH₃

I-381
H, CH₂CH₃
H
H
H
CH₃
CH₃

I-382
H, CH(CH₃)₂
H
H
H
CH₃
CH₃

I-383
H, C₃H₇
H
H
H
CH₃
CH₃

I-384
H, C(═O)CH₃
H
H
H
CH₃
CH₃

I-385
H, C(═O)CH₂CH₃
H
H
H
CH₃
CH₃

I-386
H, C(═O)C₃H₇
H
H
H
CH₃
CH₃

I-387
H, CH₂CN
H
H
H
CH₃
CH₃

I-388
H, H
CH₃
H
H
CH₃
CH₃

I-389
H, CH₃
CH₃
H
H
CH₃
CH₃

I-390
H, CH₂CH₃
CH₃
H
H
CH₃
CH₃

I-391
H, CH(CH₃)₂
CH₃
H
H
CH₃
CH₃

I-392
H, C₃H₇
CH₃
H
H
CH₃
CH₃

I-393
H, C(═O)CH₃
CH₃
H
H
CH₃
CH₃

I-394
H, C(═O)CH₂CH₃
CH₃
H
H
CH₃
CH₃

I-395
H, C(═O)C₃H₇
CH₃
H
H
CH₃
CH₃

I-396
H, CH₂CN
CH₃
H
H
CH₃
CH₃

I-397
H, H
H
CH₃
H
CH₃
CH₃

I-398
H, CH₃
H
CH₃
H
CH₃
CH₃

I-399
H, CH₂CH₃
H
CH₃
H
CH₃
CH₃

I-400
H, CH(CH₃)₂
H
CH₃
H
CH₃
CH₃

I-401
H, C₃H₇
H
CH₃
H
CH₃
CH₃

I-402
H, C(═O)CH₃
H
CH₃
H
CH₃
CH₃

I-403
H, C(═O)CH₂CH₃
H
CH₃
H
CH₃
CH₃

I-404
H, C(═O)C₃H₇
H
CH₃
H
CH₃
CH₃

I-405
H, CH₂CN
H
CH₃
H
CH₃
CH₃

I-406
H, H
CH₃
CH₃
H
CH₃
CH₃

I-407
H, CH₃
CH₃
CH₃
H
CH₃
CH₃

I-408
H, CH₂CH₃
CH₃
CH₃
H
CH₃
CH₃

I-409
H, CH(CH₃)₂
CH₃
CH₃
H
CH₃
CH₃

I-410
H, C₃H₇
CH₃
CH₃
H
CH₃
CH₃

I-411
H, C(═O)CH₃
CH₃
CH₃
H
CH₃
CH₃

I-412
H, C(═O)CH₂CH₃
CH₃
CH₃
H
CH₃
CH₃

I-413
H, C(═O)C₃H₇
CH₃
CH₃
H
CH₃
CH₃

I-414
H, CH₂CN
CH₃
CH₃
H
CH₃
CH₃

I-415
H, H
H
F
H
CH₃
CH₃

I-416
H, CH₃
H
F
H
CH₃
CH₃

I-417
H, CH₂CH₃
H
F
H
CH₃
CH₃

I-418
H, CH(CH₃)₂
H
F
H
CH₃
CH₃

I-419
H, C₃H₇
H
F
H
CH₃
CH₃

I-420
H, C(═O)CH₃
H
F
H
CH₃
CH₃

I-421
H, C(═O)CH₂CH₃
H
F
H
CH₃
CH₃

I-422
H, C(═O)C₃H₇
H
F
H
CH₃
CH₃

I-423
H, CH₂CN
H
F
H
CH₃
CH₃

I-424
H, H
CH₃
F
H
CH₃
CH₃

I-425
H, CH₃
CH₃
F
H
CH₃
CH₃

I-426
H, CH₂CH₃
CH₃
F
H
CH₃
CH₃

I-427
H, CH(CH₃)₂
CH₃
F
H
CH₃
CH₃

I-428
H, C₃H₇
CH₃
F
H
CH₃
CH₃

I-429
H, C(═O)CH₃
CH₃
F
H
CH₃
CH₃

I-430
H, C(═O)CH₂CH₃
CH₃
F
H
CH₃
CH₃

I-431
H, C(═O)C₃H₇
CH₃
F
H
CH₃
CH₃

I-432
H, CH₂CN
CH₃
F
H
CH₃
CH₃

I-433
H, H
H
CH₃
CH₃
CH₃
CH₃

I-434
H, CH₃
H
CH₃
CH₃
CH₃
CH₃

I-435
H, CH₂CH₃
H
CH₃
CH₃
CH₃
CH₃

I-436
H, CH(CH₃)₂
H
CH₃
CH₃
CH₃
CH₃

I-437
H, C₃H₇
H
CH₃
CH₃
CH₃
CH₃

I-438
H, C(═O)CH₃
H
CH₃
CH₃
CH₃
CH₃

I-439
H, C(═O)CH₂CH₃
H
CH₃
CH₃
CH₃
CH₃

I-440
H, C(═O)C₃H₇
H
CH₃
CH₃
CH₃
CH₃

I-441
H, CH₂CN
H
CH₃
CH₃
CH₃
CH₃

I-442
H, H
CH₃
CH₃
CH₃
CH₃
CH₃

I-443
H, CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-444
H, CH₂CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-445
H, CH(CH₃)₂
CH₃
CH₃
CH₃
CH₃
CH₃

I-446
H, C₃H₇
CH₃
CH₃
CH₃
CH₃
CH₃

I-447
H, C(═O)CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-448
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-449
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
CH₃
CH₃

I-450
H, CH₂CN
CH₃
CH₃
CH₃
CH₃
CH₃

I-451
H, H
H
F
CH₃
CH₃
CH₃

I-452
H, CH₃
H
F
CH₃
CH₃
CH₃

I-453
H, CH₂CH₃
H
F
CH₃
CH₃
CH₃

I-454
H, CH(CH₃)₂
H
F
CH₃
CH₃
CH₃

I-455
H, C₃H₇
H
F
CH₃
CH₃
CH₃

I-456
H, C(═O)CH₃
H
F
CH₃
CH₃
CH₃

I-457
H, C(═O)CH₂CH₃
H
F
CH₃
CH₃
CH₃

I-458
H, C(═O)C₃H₇
H
F
CH₃
CH₃
CH₃

I-459
H, CH₂CN
H
F
CH₃
CH₃
CH₃

I-460
H, H
CH₃
F
CH₃
CH₃
CH₃

I-461
H, CH₃
CH₃
F
CH₃
CH₃
CH₃

I-462
H, CH₂CH₃
CH₃
F
CH₃
CH₃
CH₃

I-463
H, CH(CH₃)₂
CH₃
F
CH₃
CH₃
CH₃

I-464
H, C₃H₇
CH₃
F
CH₃
CH₃
CH₃

I-465
H, C(═O)CH₃
CH₃
F
CH₃
CH₃
CH₃

I-466
H, C(═O)CH₂CH₃
CH₃
F
CH₃
CH₃
CH₃

I-467
H, C(═O)C₃H₇
CH₃
F
CH₃
CH₃
CH₃

I-468
H, CH₂CN
CH₃
F
CH₃
CH₃
CH₃

I-469
H, H
H
F
F
H
H

I-470
H, CH₃
H
F
F
H
H

I-471
H, CH₂CH₃
H
F
F
H
H

I-472
H, CH(CH₃)₂
H
F
F
H
H

I-473
H, C₃H₇
H
F
F
H
H

I-474
H, C(═O)CH₃
H
F
F
H
H

I-475
H, C(═O)CH₂CH₃
H
F
F
H
H

I-476
H, C(═O)C₃H₇
H
F
F
H
H

I-477
H, CH₂CN
H
F
F
H
H

I-478
H, H
CH₃
F
F
H
H

I-479
H, CH₃
CH₃
F
F
H
H

I-480
H, CH₂CH₃
CH₃
F
F
H
H

I-481
H, CH(CH₃)₂
CH₃
F
F
H
H

I-482
H, C₃H₇
CH₃
F
F
H
H

I-483
H, C(═O)CH₃
CH₃
F
F
H
H

I-484
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-485
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-486
H, CH₂CN
CH₃
F
F
H
H

I-487
H, H
H
C═O
CH₃
CH₃

I-488
H, CH₃
H
C═O
CH₃
CH₃

I-489
H, CH₂CH₃
H
C═O
CH₃
CH₃

I-490
H, CH(CH₃)₂
H
C═O
CH₃
CH₃

I-491
H, C₃H₇
H
C═O
CH₃
CH₃

I-492
H, C(═O)CH₃
H
C═O
CH₃
CH₃

I-493
H, C(═O)CH₂CH₃
H
C═O
CH₃
CH₃

I-494
H, C(═O)C₃H₇
H
C═O
CH₃
CH₃

I-495
H, CH₂CN
H
C═O
CH₃
CH₃

I-496
H, H
CH₃
C═O
CH₃
CH₃

I-497
H, CH₃
CH₃
C═O
CH₃
CH₃

I-498
H, CH₂CH₃
CH₃
C═O
CH₃
CH₃

I-499
H, CH(CH₃)₂
CH₃
C═O
CH₃
CH₃

I-500
H, C₃H₇
CH₃
C═O
CH₃
CH₃

I-501
H, C(═O)CH₃
CH₃
C═O
CH₃
CH₃

I-502
H, C(═O)CH₂CH₃
CH₃
C═O
CH₃
CH₃

I-503
H, C(═O)C₃H₇
CH₃
C═O
CH₃
CH₃

I-504
H, CH₂CN
CH₃
C═O
CH₃
CH₃

I-505
H, H
H
H
H
F
CH₃

I-506
H, CH₃
H
H
H
F
CH₃

I-507
H, CH₂CH₃
H
H
H
F
CH₃

I-508
H, CH(CH₃)₂
H
H
H
F
CH₃

I-509
H, C₃H₇
H
H
H
F
CH₃

I-510
H, C(═O)CH₃
H
H
H
F
CH₃

I-511
H, C(═O)CH₂CH₃
H
H
H
F
CH₃

I-512
H, C(═O)C₃H₇
H
H
H
F
CH₃

I-513
H, CH₂CN
H
H
H
F
CH₃

I-514
H, H
CH₃
H
H
F
CH₃

I-515
H, CH₃
CH₃
H
H
F
CH₃

I-516
H, CH₂CH₃
CH₃
H
H
F
CH₃

I-517
H, CH(CH₃)₂
CH₃
H
H
F
CH₃

I-518
H, C₃H₇
CH₃
H
H
F
CH₃

I-519
H, C(═O)CH₃
CH₃
H
H
F
CH₃

I-520
H, C(═O)CH₂CH₃
CH₃
H
H
F
CH₃

I-521
H, C(═O)C₃H₇
CH₃
H
H
F
CH₃

I-522
H, CH₂CN
CH₃
H
H
F
CH₃

I-523
H, H
H
CH₃
H
F
CH₃

I-524
H, CH₃
H
CH₃
H
F
CH₃

I-525
H, CH₂CH₃
H
CH₃
H
F
CH₃

I-526
H, CH(CH₃)₂
H
CH₃
H
F
CH₃

I-527
H, C₃H₇
H
CH₃
H
F
CH₃

I-528
H, C(═O)CH₃
H
CH₃
H
F
CH₃

I-529
H, C(═O)CH₂CH₃
H
CH₃
H
F
CH₃

I-530
H, C(═O)C₃H₇
H
CH₃
H
F
CH₃

I-531
H, CH₂CN
H
CH₃
H
F
CH₃

I-532
H, H
CH₃
CH₃
H
F
CH₃

I-533
H, CH₃
CH₃
CH₃
H
F
CH₃

I-534
H, CH₂CH₃
CH₃
CH₃
H
F
CH₃

I-535
H, CH(CH₃)₂
CH₃
CH₃
H
F
CH₃

I-536
H, C₃H₇
CH₃
CH₃
H
F
CH₃

I-537
H, C(═O)CH₃
CH₃
CH₃
H
F
CH₃

I-538
H, C(═O)CH₂CH₃
CH₃
CH₃
H
F
CH₃

I-539
H, C(═O)C₃H₇
CH₃
CH₃
H
F
CH₃

I-540
H, CH₂CN
CH₃
CH₃
H
F
CH₃

I-541
H, H
H
F
H
F
CH₃

I-542
H, CH₃
H
F
H
F
CH₃

I-543
H, CH₂CH₃
H
F
H
F
CH₃

I-544
H, CH(CH₃)₂
H
F
H
F
CH₃

I-545
H, C₃H₇
H
F
H
F
CH₃

I-546
H, C(═O)CH₃
H
F
H
F
CH₃

I-547
H, C(═O)CH₂CH₃
H
F
H
F
CH₃

I-548
H, C(═O)C₃H₇
H
F
H
F
CH₃

I-549
H, CH₂CN
H
F
H
F
CH₃

I-550
H, H
CH₃
F
H
F
CH₃

I-551
H, CH₃
CH₃
F
H
F
CH₃

I-552
H, CH₂CH₃
CH₃
F
H
F
CH₃

I-553
H, CH(CH₃)₂
CH₃
F
H
F
CH₃

I-554
H, C₃H₇
CH₃
F
H
F
CH₃

I-555
H, C(═O)CH₃
CH₃
F
H
F
CH₃

I-556
H, C(═O)CH₂CH₃
CH₃
F
H
F
CH₃

I-557
H, C(═O)C₃H₇
CH₃
F
H
F
CH₃

I-558
H, CH₂CN
CH₃
F
H
F
CH₃

I-559
H, H
H
CH₃
CH₃
F
CH₃

I-560
H, CH₃
H
CH₃
CH₃
F
CH₃

I-561
H, CH₂CH₃
H
CH₃
CH₃
F
CH₃

I-562
H, CH(CH₃)₂
H
CH₃
CH₃
F
CH₃

I-563
H, C₃H₇
H
CH₃
CH₃
F
CH₃

I-564
H, C(═O)CH₃
H
CH₃
CH₃
F
CH₃

I-565
H, C(═O)CH₂CH₃
H
CH₃
CH₃
F
CH₃

I-566
H, C(═O)C₃H₇
H
CH₃
CH₃
F
CH₃

I-567
H, CH₂CN
H
CH₃
CH₃
F
CH₃

I-568
H, H
CH₃
CH₃
CH₃
F
CH₃

I-569
H, CH₃
CH₃
CH₃
CH₃
F
CH₃

I-570
H, CH₂CH₃
CH₃
CH₃
CH₃
F
CH₃

I-571
H, CH(CH₃)₂
CH₃
CH₃
CH₃
F
CH₃

I-572
H, C₃H₇
CH₃
CH₃
CH₃
F
CH₃

I-573
H, C(═O)CH₃
CH₃
CH₃
CH₃
F
CH₃

I-574
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
CH₃

I-575
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
CH₃

I-576
H, CH₂CN
CH₃
CH₃
CH₃
F
CH₃

I-577
H, H
H
F
CH₃
F
CH₃

I-578
H, CH₃
H
F
CH₃
F
CH₃

I-579
H, CH₂CH₃
H
F
CH₃
F
CH₃

I-580
H, CH(CH₃)₂
H
F
CH₃
F
CH₃

I-581
H, C₃H₇
H
F
CH₃
F
CH₃

I-582
H, C(═O)CH₃
H
F
CH₃
F
CH₃

I-583
H, C(═O)CH₂CH₃
H
F
CH₃
F
CH₃

I-584
H, C(═O)C₃H₇
H
F
CH₃
F
CH₃

I-585
H, CH₂CN
H
F
CH₃
F
CH₃

I-586
H, H
CH₃
F
CH₃
F
CH₃

I-587
H, CH₃
CH₃
F
CH₃
F
CH₃

I-588
H, CH₂CH₃
CH₃
F
CH₃
F
CH₃

I-589
H, CH(CH₃)₂
CH₃
F
CH₃
F
CH₃

I-590
H, C₃H₇
CH₃
F
CH₃
F
CH₃

I-591
H, C(═O)CH₃
CH₃
F
CH₃
F
CH₃

I-592
H, C(═O)CH₂CH₃
CH₃
F
CH₃
F
CH₃

I-593
H, C(═O)C₃H₇
CH₃
F
CH₃
F
CH₃

I-594
H, CH₂CN
CH₃
F
CH₃
F
CH₃

I-595
H, H
H
F
F
H
H

I-596
H, CH₃
H
F
F
H
H

I-597
H, CH₂CH₃
H
F
F
H
H

I-598
H, CH(CH₃)₂
H
F
F
H
H

I-599
H, C₃H₇
H
F
F
H
H

I-600
H, C(═O)CH₃
H
F
F
H
H

I-601
H, C(═O)CH₂CH₃
H
F
F
H
H

I-602
H, C(═O)C₃H₇
H
F
F
H
H

I-603
H, CH₂CN
H
F
F
H
H

I-604
H, H
CH₃
F
F
H
H

I-605
H, CH₃
CH₃
F
F
H
H

I-606
H, CH₂CH₃
CH₃
F
F
H
H

I-607
H, CH(CH₃)₂
CH₃
F
F
H
H

I-608
H, C₃H₇
CH₃
F
F
H
H

I-609
H, C(═O)CH₃
CH₃
F
F
H
H

I-610
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-611
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-612
H, CH₂CN
CH₃
F
F
H
H

I-613
H, H
H
C═O
F
CH₃

I-614
H, CH₃
H
C═O
F
CH₃

I-615
H, CH₂CH₃
H
C═O
F
CH₃

I-616
H, CH(CH₃)₂
H
C═O
F
CH₃

I-617
H, C₃H₇
H
C═O
F
CH₃

I-618
H, C(═O)CH₃
H
C═O
F
CH₃

I-619
H, C(═O)CH₂CH₃
H
C═O
F
CH₃

I-620
H, C(═O)C₃H₇
H
C═O
F
CH₃

I-621
H, CH₂CN
H
C═O
F
CH₃

I-622
H, H
CH₃
C═O
F
CH₃

I-623
H, CH₃
CH₃
C═O
F
CH₃

I-624
H, CH₂CH₃
CH₃
C═O
F
CH₃

I-625
H, CH(CH₃)₂
CH₃
C═O
F
CH₃

I-626
H, C₃H₇
CH₃
C═O
F
CH₃

I-627
H, C(═O)CH₃
CH₃
C═O
F
CH₃

I-628
H, C(═O)CH₂CH₃
CH₃
C═O
F
CH₃

I-629
H, C(═O)C₃H₇
CH₃
C═O
F
CH₃

I-630
H, CH₂CN
CH₃
C═O
F
CH₃

I-631
H, H
H
H
H
F
F

I-632
H, CH₃
H
H
H
F
F

I-633
H, CH₂CH₃
H
H
H
F
F

I-634
H, CH(CH₃)₂
H
H
H
F
F

I-635
H, C₃H₇
H
H
H
F
F

I-636
H, C(═O)CH₃
H
H
H
F
F

I-637
H, C(═O)CH₂CH₃
H
H
H
F
F

I-638
H, C(═O)C₃H₇
H
H
H
F
F

I-639
H, CH₂CN
H
H
H
F
F

I-640
H, H
CH₃
H
H
F
F

I-641
H, CH₃
CH₃
H
H
F
F

I-642
H, CH₂CH₃
CH₃
H
H
F
F

I-643
H, CH(CH₃)₂
CH₃
H
H
F
F

I-644
H, C₃H₇
CH₃
H
H
F
F

I-645
H, C(═O)CH₃
CH₃
H
H
F
F

I-646
H, C(═O)CH₂CH₃
CH₃
H
H
F
F

I-647
H, C(═O)C₃H₇
CH₃
H
H
F
F

I-648
H, CH₂CN
CH₃
H
H
F
F

I-649
H, H
H
CH₃
H
F
F

I-650
H, CH₃
H
CH₃
H
F
F

I-651
H, CH₂CH₃
H
CH₃
H
F
F

I-652
H, CH(CH₃)₂
H
CH₃
H
F
F

I-653
H, C₃H₇
H
CH₃
H
F
F

I-654
H, C(═O)CH₃
H
CH₃
H
F
F

I-655
H, C(═O)CH₂CH₃
H
CH₃
H
F
F

I-656
H, C(═O)C₃H₇
H
CH₃
H
F
F

I-657
H, CH₂CN
H
CH₃
H
F
F

I-658
H, H
CH₃
CH₃
H
F
F

I-659
H, CH₃
CH₃
CH₃
H
F
F

I-660
H, CH₂CH₃
CH₃
CH₃
H
F
F

I-661
H, CH(CH₃)₂
CH₃
CH₃
H
F
F

I-662
H, C₃H₇
CH₃
CH₃
H
F
F

I-663
H, C(═O)CH₃
CH₃
CH₃
H
F
F

I-664
H, C(═O)CH₂CH₃
CH₃
CH₃
H
F
F

I-665
H, C(═O)C₃H₇
CH₃
CH₃
H
F
F

I-666
H, CH₂CN
CH₃
CH₃
H
F
F

I-667
H, H
H
F
H
F
F

I-668
H, CH₃
H
F
H
F
F

I-669
H, CH₂CH₃
H
F
H
F
F

I-670
H, CH(CH₃)₂
H
F
H
F
F

I-671
H, C₃H₇
H
F
H
F
F

I-672
H, C(═O)CH₃
H
F
H
F
F

I-673
H, C(═O)CH₂CH₃
H
F
H
F
F

I-674
H, C(═O)C₃H₇
H
F
H
F
F

I-675
H, CH₂CN
H
F
H
F
F

I-676
H, H
CH₃
F
H
F
F

I-677
H, CH₃
CH₃
F
H
F
F

I-678
H, CH₂CH₃
CH₃
F
H
F
F

I-679
H, CH(CH₃)₂
CH₃
F
H
F
F

I-680
H, C₃H₇
CH₃
F
H
F
F

I-681
H, C(═O)CH₃
CH₃
F
H
F
F

I-682
H, C(═O)CH₂CH₃
CH₃
F
H
F
F

I-683
H, C(═O)C₃H₇
CH₃
F
H
F
F

I-684
H, CH₂CN
CH₃
F
H
F
F

I-685
H, H
H
CH₃
CH₃
F
F

I-686
H, CH₃
H
CH₃
CH₃
F
F

I-687
H, CH₂CH₃
H
CH₃
CH₃
F
F

I-688
H, CH(CH₃)₂
H
CH₃
CH₃
F
F

I-689
H, C₃H₇
H
CH₃
CH₃
F
F

I-690
H, C(═O)CH₃
H
CH₃
CH₃
F
F

I-691
H, C(═O)CH₂CH₃
H
CH₃
CH₃
F
F

I-692
H, C(═O)C₃H₇
H
CH₃
CH₃
F
F

I-693
H, CH₂CN
H
CH₃
CH₃
F
F

I-694
H, H
CH₃
CH₃
CH₃
F
F

I-695
H, CH₃
CH₃
CH₃
CH₃
F
F

I-696
H, CH₂CH₃
CH₃
CH₃
CH₃
F
F

I-697
H, CH(CH₃)₂
CH₃
CH₃
CH₃
F
F

I-698
H, C₃H₇
CH₃
CH₃
CH₃
F
F

I-699
H, C(═O)CH₃
CH₃
CH₃
CH₃
F
F

I-700
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
F

I-701
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
F

I-702
H, CH₂CN
CH₃
CH₃
CH₃
F
F

I-703
H, H
H
F
CH₃
F
F

I-704
H, CH₃
H
F
CH₃
F
F

I-705
H, CH₂CH₃
H
F
CH₃
F
F

I-706
H, CH(CH₃)₂
H
F
CH₃
F
F

I-707
H, C₃H₇
H
F
CH₃
F
F

I-708
H, C(═O)CH₃
H
F
CH₃
F
F

I-709
H, C(═O)CH₂CH₃
H
F
CH₃
F
F

I-710
H, C(═O)C₃H₇
H
F
CH₃
F
F

I-711
H, CH₂CN
H
F
CH₃
F
F

I-712
H, H
CH₃
F
CH₃
F
F

I-713
H, CH₃
CH₃
F
CH₃
F
F

I-714
H, CH₂CH₃
CH₃
F
CH₃
F
F

I-715
H, CH(CH₃)₂
CH₃
F
CH₃
F
F

I-716
H, C₃H₇
CH₃
F
CH₃
F
F

I-717
H, C(═O)CH₃
CH₃
F
CH₃
F
F

I-718
H, C(═O)CH₂CH₃
CH₃
F
CH₃
F
F

I-719
H, C(═O)C₃H₇
CH₃
F
CH₃
F
F

I-720
H, CH₂CN
CH₃
F
CH₃
F
F

I-721
H, H
H
F
F
H
H

I-722
H, CH₃
H
F
F
H
H

I-723
H, CH₂CH₃
H
F
F
H
H

I-724
H, CH(CH₃)₂
H
F
F
H
H

I-725
H, C₃H₇
H
F
F
H
H

I-726
H, C(═O)CH₃
H
F
F
H
H

I-727
H, C(═O)CH₂CH₃
H
F
F
H
H

I-728
H, C(═O)C₃H₇
H
F
F
H
H

I-729
H, CH₂CN
H
F
F
H
H

I-730
H, H
CH₃
F
F
H
H

I-731
H, CH₃
CH₃
F
F
H
H

I-732
H, CH₂CH₃
CH₃
F
F
H
H

I-733
H, CH(CH₃)₂
CH₃
F
F
H
H

I-734
H, C₃H₇
CH₃
F
F
H
H

I-735
H, C(═O)CH₃
CH₃
F
F
H
H

I-736
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-737
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-738
H, CH₂CN
CH₃
F
F
H
H

I-739
H, H
H
C═O
F
F

I-740
H, CH₃
H
C═O
F
F

I-741
H, CH₂CH₃
H
C═O
F
F

I-742
H, CH(CH₃)₂
H
C═O
F
F

I-743
H, C₃H₇
H
C═O
F
F

I-744
H, C(═O)CH₃
H
C═O
F
F

I-745
H, C(═O)CH₂CH₃
H
C═O
F
F

I-746
H, C(═O)C₃H₇
H
C═O
F
F

I-747
H, CH₂CN
H
C═O
F
F

I-748
H, H
CH₃
C═O
F
F

I-749
H, CH₃
CH₃
C═O
F
F

I-750
H, CH₂CH₃
CH₃
C═O
F
F

I-751
H, CH(CH₃)₂
CH₃
C═O
F
F

I-752
H, C₃H₇
CH₃
C═O
F
F

I-753
H, C(═O)CH₃
CH₃
C═O
F
F

I-754
H, C(═O)CH₂CH₃
CH₃
C═O
F
F

I-755
H, C(═O)C₃H₇
CH₃
C═O
F
F

I-756
H, CH₂CN
CH₃
C═O
F
F

I-1
H, H
H
H
H
H
H

I-2
H, CH₃
H
H
H
H
H

I-3
H, CH₂CH₃
H
H
H
H
H

I-4
H, CH(CH₃)₂
H
H
H
H
H

I-5
H, C₃H₇
H
H
H
H
H

I-6
H, C(═O)CH₃
H
H
H
H
H

I-7
H, C(═O)CH₂CH₃
H
H
H
H
H

I-8
H, C(═O)C₃H₇
H
H
H
H
H

I-9
H, CH₂CN
H
H
H
H
H

I-10
H, H
CH₃
H
H
H
H

I-11
H, CH₃
CH₃
H
H
H
H

I-12
H, CH₂CH₃
CH₃
H
H
H
H

I-13
H, CH(CH₃)₂
CH₃
H
H
H
H

I-14
H, C₃H₇
CH₃
H
H
H
H

I-15
H, C(═O)CH₃
CH₃
H
H
H
H

I-16
H, C(═O)CH₂CH₃
CH₃
H
H
H
H

I-17
H, C(═O)C₃H₇
CH₃
H
H
H
H

I-18
H, CH₂CN
CH₃
H
H
H
H

I-19
H, H
H
CH₃
H
H
H

I-20
H, CH₃
H
CH₃
H
H
H

I-21
H, CH₂CH₃
H
CH₃
H
H
H

I-22
H, CH(CH₃)₂
H
CH₃
H
H
H

I-23
H, C₃H₇
H
CH₃
H
H
H

I-24
H, C(═O)CH₃
H
CH₃
H
H
H

I-25
H, C(═O)CH₂CH₃
H
CH₃
H
H
H

I-26
H, C(═O)C₃H₇
H
CH₃
H
H
H

I-27
H, CH₂CN
H
CH₃
H
H
H

I-28
H, H
CH₃
CH₃
H
H
H

I-29
H, CH₃
CH₃
CH₃
H
H
H

I-30
H, CH₂CH₃
CH₃
CH₃
H
H
H

I-31
H, CH(CH₃)₂
CH₃
CH₃
H
H
H

I-32
H, C₃H₇
CH₃
CH₃
H
H
H

I-33
H, C(═O)CH₃
CH₃
CH₃
H
H
H

I-34
H, C(═O)CH₂CH₃
CH₃
CH₃
H
H
H

I-35
H, C(═O)C₃H₇
CH₃
CH₃
H
H
H

I-36
H, CH₂CN
CH₃
CH₃
H
H
H

I-37
H, H
H
F
H
H
H

I-38
H, CH₃
H
F
H
H
H

I-39
H, CH₂CH₃
H
F
H
H
H

I-40
H, CH(CH₃)₂
H
F
H
H
H

I-41
H, C₃H₇
H
F
H
H
H

I-42
H, C(═O)CH₃
H
F
H
H
H

I-43
H, C(═O)CH₂CH₃
H
F
H
H
H

I-44
H, C(═O)C₃H₇
H
F
H
H
H

I-45
H, CH₂CN
H
F
H
H
H

I-46
H, H
CH₃
F
H
H
H

I-47
H, CH₃
CH₃
F
H
H
H

I-48
H, CH₂CH₃
CH₃
F
H
H
H

I-49
H, CH(CH₃)₂
CH₃
F
H
H
H

I-50
H, C₃H₇
CH₃
F
H
H
H

I-51
H, C(═O)CH₃
CH₃
F
H
H
H

I-52
H, C(═O)CH₂CH₃
CH₃
F
H
H
H

I-53
H, C(═O)C₃H₇
CH₃
F
H
H
H

I-54
H, CH₂CN
CH₃
F
H
H
H

I-55
H, H
H
CH₃
CH₃
H
H

I-56
H, CH₃
H
CH₃
CH₃
H
H

I-57
H, CH₂CH₃
H
CH₃
CH₃
H
H

I-58
H, CH(CH₃)₂
H
CH₃
CH₃
H
H

I-59
H, C₃H₇
H
CH₃
CH₃
H
H

I-60
H, C(═O)CH₃
H
CH₃
CH₃
H
H

I-61
H, C(═O)CH₂CH₃
H
CH₃
CH₃
H
H

I-62
H, C(═O)C₃H₇
H
CH₃
CH₃
H
H

I-63
H, CH₂CN
H
CH₃
CH₃
H
H

I-64
H, H
CH₃
CH₃
CH₃
H
H

I-65
H, CH₃
CH₃
CH₃
CH₃
H
H

I-66
H, CH₂CH₃
CH₃
CH₃
CH₃
H
H

I-67
H, CH(CH₃)₂
CH₃
CH₃
CH₃
H
H

I-68
H, C₃H₇
CH₃
CH₃
CH₃
H
H

I-69
H, C(═O)CH₃
CH₃
CH₃
CH₃
H
H

I-70
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
H
H

I-71
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
H
H

I-72
H, CH₂CN
CH₃
CH₃
CH₃
H
H

I-73
H, H
H
F
CH₃
H
H

I-74
H, CH₃
H
F
CH₃
H
H

I-75
H, CH₂CH₃
H
F
CH₃
H
H

I-76
H, CH(CH₃)₂
H
F
CH₃
H
H

I-77
H, C₃H₇
H
F
CH₃
H
H

I-78
H, C(═O)CH₃
H
F
CH₃
H
H

I-79
H, C(═O)CH₂CH₃
H
F
CH₃
H
H

I-80
H, C(═O)C₃H₇
H
F
CH₃
H
H

I-81
H, CH₂CN
H
F
CH₃
H
H

I-82
H, H
CH₃
F
CH₃
H
H

I-83
H, CH₃
CH₃
F
CH₃
H
H

I-84
H, CH₂CH₃
CH₃
F
CH₃
H
H

I-85
H, CH(CH₃)₂
CH₃
F
CH₃
H
H

I-86
H, C₃H₇
CH₃
F
CH₃
H
H

I-87
H, C(═O)CH₃
CH₃
F
CH₃
H
H

I-88
H, C(═O)CH₂CH₃
CH₃
F
CH₃
H
H

I-89
H, C(═O)C₃H₇
CH₃
F
CH₃
H
H

I-90
H, CH₂CN
CH₃
F
CH₃
H
H

I-91
H, H
H
F
F
H
H

I-92
H, CH₃
H
F
F
H
H

I-93
H, CH₂CH₃
H
F
F
H
H

I-94
H, CH(CH₃)₂
H
F
F
H
H

I-95
H, C₃H₇
H
F
F
H
H

I-96
H, C(═O)CH₃
H
F
F
H
H

I-97
H, C(═O)CH₂CH₃
H
F
F
H
H

I-98
H, C(═O)C₃H₇
H
F
F
H
H

I-99
H, CH₂CN
H
F
F
H
H

I-100
H, H
CH₃
F
F
H
H

I-101
H, CH₃
CH₃
F
F
H
H

I-102
H, CH₂CH₃
CH₃
F
F
H
H

I-103
H, CH(CH₃)₂
CH₃
F
F
H
H

I-104
H, C₃H₇
CH₃
F
F
H
H

I-105
H, C(═O)CH₃
CH₃
F
F
H
H

I-106
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-107
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-108
H, CH₂CN
CH₃
F
F
H
H

I-109
H, H
H
C═O
H
H

I-110
H, CH₃
H
C═O
H
H

I-111
H, CH₂CH₃
H
C═O
H
H

I-112
H, CH(CH₃)₂
H
C═O
H
H

I-113
H, C₃H₇
H
C═O
H
H

I-114
H, C(═O)CH₃
H
C═O
H
H

I-115
H, C(═O)CH₂CH₃
H
C═O
H
H

I-116
H, C(═O)C₃H₇
H
C═O
H
H

I-117
H, CH₂CN
H
C═O
H
H

I-118
H, H
CH₃
C═O
H
H

I-119
H, CH₃
CH₃
C═O
H
H

I-120
H, CH₂CH₃
CH₃
C═O
H
H

I-121
H, CH(CH₃)₂
CH₃
C═O
H
H

I-122
H, C₃H₇
CH₃
C═O
H
H

I-123
H, C(═O)CH₃
CH₃
C═O
H
H

I-124
H, C(═O)CH₂CH₃
CH₃
C═O
H
H

I-125
H, C(═O)C₃H₇
CH₃
C═O
H
H

I-126
H, CH₂CN
CH₃
C═O
H
H

I-127
H, H
H
H
H
CH₃
H

I-128
H, CH₃
H
H
H
CH₃
H

I-129
H, CH₂CH₃
H
H
H
CH₃
H

I-130
H, CH(CH₃)₂
H
H
H
CH₃
H

I-131
H, C₃H₇
H
H
H
CH₃
H

I-132
H, C(═O)CH₃
H
H
H
CH₃
H

I-133
H, C(═O)CH₂CH₃
H
H
H
CH₃
H

I-134
H, C(═O)C₃H₇
H
H
H
CH₃
H

I-135
H, CH₂CN
H
H
H
CH₃
H

I-136
H, H
CH₃
H
H
CH₃
H

I-137
H, CH₃
CH₃
H
H
CH₃
H

I-138
H, CH₂CH₃
CH₃
H
H
CH₃
H

I-139
H, CH(CH₃)₂
CH₃
H
H
CH₃
H

I-140
H, C₃H₇
CH₃
H
H
CH₃
H

I-141
H, C(═O)CH₃
CH₃
H
H
CH₃
H

I-142
H, C(═O)CH₂CH₃
CH₃
H
H
CH₃
H

I-143
H, C(═O)C₃H₇
CH₃
H
H
CH₃
H

I-144
H, CH₂CN
CH₃
H
H
CH₃
H

I-145
H, H
H
CH₃
H
CH₃
H

I-146
H, CH₃
H
CH₃
H
CH₃
H

I-147
H, CH₂CH₃
H
CH₃
H
CH₃
H

I-148
H, CH(CH₃)₂
H
CH₃
H
CH₃
H

I-149
H, C₃H₇
H
CH₃
H
CH₃
H

I-150
H, C(═O)CH₃
H
CH₃
H
CH₃
H

I-151
H, C(═O)CH₂CH₃
H
CH₃
H
CH₃
H

I-152
H, C(═O)C₃H₇
H
CH₃
H
CH₃
H

I-153
H, CH₂CN
H
CH₃
H
CH₃
H

I-154
H, H
CH₃
CH₃
H
CH₃
H

I-155
H, CH₃
CH₃
CH₃
H
CH₃
H

I-156
H, CH₂CH₃
CH₃
CH₃
H
CH₃
H

I-157
H, CH(CH₃)₂
CH₃
CH₃
H
CH₃
H

I-158
H, C₃H₇
CH₃
CH₃
H
CH₃
H

I-159
H, C(═O)CH₃
CH₃
CH₃
H
CH₃
H

I-160
H, C(═O)CH₂CH₃
CH₃
CH₃
H
CH₃
H

I-161
H, C(═O)C₃H₇
CH₃
CH₃
H
CH₃
H

I-162
H, CH₂CN
CH₃
CH₃
H
CH₃
H

I-163
H, H
H
F
H
CH₃
H

I-164
H, CH₃
H
F
H
CH₃
H

I-165
H, CH₂CH₃
H
F
H
CH₃
H

I-166
H, CH(CH₃)₂
H
F
H
CH₃
H

I-167
H, C₃H₇
H
F
H
CH₃
H

I-168
H, C(═O)CH₃
H
F
H
CH₃
H

I-169
H, C(═O)CH₂CH₃
H
F
H
CH₃
H

I-170
H, C(═O)C₃H₇
H
F
H
CH₃
H

I-171
H, CH₂CN
H
F
H
CH₃
H

I-172
H, H
CH₃
F
H
CH₃
H

I-173
H, CH₃
CH₃
F
H
CH₃
H

I-174
H, CH₂CH₃
CH₃
F
H
CH₃
H

I-175
H, CH(CH₃)₂
CH₃
F
H
CH₃
H

I-176
H, C₃H₇
CH₃
F
H
CH₃
H

I-177
H, C(═O)CH₃
CH₃
F
H
CH₃
H

I-178
H, C(═O)CH₂CH₃
CH₃
F
H
CH₃
H

I-179
H, C(═O)C₃H₇
CH₃
F
H
CH₃
H

I-180
H, CH₂CN
CH₃
F
H
CH₃
H

I-181
H, H
H
CH₃
CH₃
CH₃
H

I-182
H, CH₃
H
CH₃
CH₃
CH₃
H

I-183
H, CH₂CH₃
H
CH₃
CH₃
CH₃
H

I-184
H, CH(CH₃)₂
H
CH₃
CH₃
CH₃
H

I-185
H, C₃H₇
H
CH₃
CH₃
CH₃
H

I-186
H, C(═O)CH₃
H
CH₃
CH₃
CH₃
H

I-187
H, C(═O)CH₂CH₃
H
CH₃
CH₃
CH₃
H

I-188
H, C(═O)C₃H₇
H
CH₃
CH₃
CH₃
H

I-189
H, CH₂CN
H
CH₃
CH₃
CH₃
H

I-190
H, H
CH₃
CH₃
CH₃
CH₃
H

I-191
H, CH₃
CH₃
CH₃
CH₃
CH₃
H

I-192
H, CH₂CH₃
CH₃
CH₃
CH₃
CH₃
H

I-193
H, CH(CH₃)₂
CH₃
CH₃
CH₃
CH₃
H

I-194
H, C₃H₇
CH₃
CH₃
CH₃
CH₃
H

I-195
H, C(═O)CH₃
CH₃
CH₃
CH₃
CH₃
H

I-196
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
CH₃
H

I-197
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
CH₃
H

I-198
H, CH₂CN
CH₃
CH₃
CH₃
CH₃
H

I-199
H, H
H
F
CH₃
CH₃
H

I-200
H, CH₃
H
F
CH₃
CH₃
H

I-201
H, CH₂CH₃
H
F
CH₃
CH₃
H

I-202
H, CH(CH₃)₂
H
F
CH₃
CH₃
H

I-203
H, C₃H₇
H
F
CH₃
CH₃
H

I-204
H, C(═O)CH₃
H
F
CH₃
CH₃
H

I-205
H, C(═O)CH₂CH₃
H
F
CH₃
CH₃
H

I-206
H, C(═O)C₃H₇
H
F
CH₃
CH₃
H

I-207
H, CH₂CN
H
F
CH₃
CH₃
H

I-208
H, H
CH₃
F
CH₃
CH₃
H

I-209
H, CH₃
CH₃
F
CH₃
CH₃
H

I-210
H, CH₂CH₃
CH₃
F
CH₃
CH₃
H

I-211
H, CH(CH₃)₂
CH₃
F
CH₃
CH₃
H

I-212
H, C₃H₇
CH₃
F
CH₃
CH₃
H

I-213
H, C(═O)CH₃
CH₃
F
CH₃
CH₃
H

I-214
H, C(═O)CH₂CH₃
CH₃
F
CH₃
CH₃
H

I-215
H, C(═O)C₃H₇
CH₃
F
CH₃
CH₃
H

I-216
H, CH₂CN
CH₃
F
CH₃
CH₃
H

I-217
H, H
H
F
F
H
H

I-218
H, CH₃
H
F
F
H
H

I-219
H, CH₂CH₃
H
F
F
H
H

I-220
H, CH(CH₃)₂
H
F
F
H
H

I-221
H, C₃H₇
H
F
F
H
H

I-222
H, C(═O)CH₃
H
F
F
H
H

I-223
H, C(═O)CH₂CH₃
H
F
F
H
H

I-224
H, C(═O)C₃H₇
H
F
F
H
H

I-225
H, CH₂CN
H
F
F
H
H

I-226
H, H
CH₃
F
F
H
H

I-227
H, CH₃
CH₃
F
F
H
H

I-228
H, CH₂CH₃
CH₃
F
F
H
H

I-229
H, CH(CH₃)₂
CH₃
F
F
H
H

I-230
H, C₃H₇
CH₃
F
F
H
H

I-231
H, C(═O)CH₃
CH₃
F
F
H
H

I-232
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-233
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-234
H, CH₂CN
CH₃
F
F
H
H

I-235
H, H
H
C═O
CH₃
H

I-236
H, CH₃
H
C═O
CH₃
H

I-237
H, CH₂CH₃
H
C═O
CH₃
H

I-238
H, CH(CH₃)₂
H
C═O
CH₃
H

I-239
H, C₃H₇
H
C═O
CH₃
H

I-240
H, C(═O)CH₃
H
C═O
CH₃
H

I-241
H, C(═O)CH₂CH₃
H
C═O
CH₃
H

I-242
H, C(═O)C₃H₇
H
C═O
CH₃
H

I-243
H, CH₂CN
H
C═O
CH₃
H

I-244
H, H
CH₃
C═O
CH₃
H

I-245
H, CH₃
CH₃
C═O
CH₃
H

I-246
H, CH₂CH₃
CH₃
C═O
CH₃
H

I-247
H, CH(CH₃)₂
CH₃
C═O
CH₃
H

I-248
H, C₃H₇
CH₃
C═O
CH₃
H

I-249
H, C(═O)CH₃
CH₃
C═O
CH₃
H

I-250
H, C(═O)CH₂CH₃
CH₃
C═O
CH₃
H

I-251
H, C(═O)C₃H₇
CH₃
C═O
CH₃
H

I-252
H, CH₂CN
CH₃
C═O
CH₃
H

I-253
H, H
H
H
H
F
H

I-254
H, CH₃
H
H
H
F
H

I-255
H, CH₂CH₃
H
H
H
F
H

I-256
H, CH(CH₃)₂
H
H
H
F
H

I-257
H, C₃H₇
H
H
H
F
H

I-258
H, C(═O)CH₃
H
H
H
F
H

I-259
H, C(═O)CH₂CH₃
H
H
H
F
H

I-260
H, C(═O)C₃H₇
H
H
H
F
H

I-261
H, CH₂CN
H
H
H
F
H

I-262
H, H
CH₃
H
H
F
H

I-263
H, CH₃
CH₃
H
H
F
H

I-264
H, CH₂CH₃
CH₃
H
H
F
H

I-265
H, CH(CH₃)₂
CH₃
H
H
F
H

I-266
H, C₃H₇
CH₃
H
H
F
H

I-267
H, C(═O)CH₃
CH₃
H
H
F
H

I-268
H, C(═O)CH₂CH₃
CH₃
H
H
F
H

I-269
H, C(═O)C₃H₇
CH₃
H
H
F
H

I-270
H, CH₂CN
CH₃
H
H
F
H

I-271
H, H
H
CH₃
H
F
H

I-272
H, CH₃
H
CH₃
H
F
H

I-273
H, CH₂CH₃
H
CH₃
H
F
H

I-274
H, CH(CH₃)₂
H
CH₃
H
F
H

I-275
H, C₃H₇
H
CH₃
H
F
H

I-276
H, C(═O)CH₃
H
CH₃
H
F
H

I-277
H, C(═O)CH₂CH₃
H
CH₃
H
F
H

I-278
H, C(═O)C₃H₇
H
CH₃
H
F
H

I-279
H, CH₂CN
H
CH₃
H
F
H

I-280
H, H
CH₃
CH₃
H
F
H

I-281
H, CH₃
CH₃
CH₃
H
F
H

I-282
H, CH₂CH₃
CH₃
CH₃
H
F
H

I-283
H, CH(CH₃)₂
CH₃
CH₃
H
F
H

I-284
H, C₃H₇
CH₃
CH₃
H
F
H

I-285
H, C(═O)CH₃
CH₃
CH₃
H
F
H

I-286
H, C(═O)CH₂CH₃
CH₃
CH₃
H
F
H

I-287
H, C(═O)C₃H₇
CH₃
CH₃
H
F
H

I-288
H, CH₂CN
CH₃
CH₃
H
F
H

I-289
H, H
H
F
H
F
H

I-290
H, CH₃
H
F
H
F
H

I-291
H, CH₂CH₃
H
F
H
F
H

I-292
H, CH(CH₃)₂
H
F
H
F
H

I-293
H, C₃H₇
H
F
H
F
H

I-294
H, C(═O)CH₃
H
F
H
F
H

I-295
H, C(═O)CH₂CH₃
H
F
H
F
H

I-296
H, C(═O)C₃H₇
H
F
H
F
H

I-297
H, CH₂CN
H
F
H
F
H

I-298
H, H
CH₃
F
H
F
H

I-299
H, CH₃
CH₃
F
H
F
H

I-300
H, CH₂CH₃
CH₃
F
H
F
H

I-301
H, CH(CH₃)₂
CH₃
F
H
F
H

I-302
H, C₃H₇
CH₃
F
H
F
H

I-303
H, C(═O)CH₃
CH₃
F
H
F
H

I-304
H, C(═O)CH₂CH₃
CH₃
F
H
F
H

I-305
H, C(═O)C₃H₇
CH₃
F
H
F
H

I-306
H, CH₂CN
CH₃
F
H
F
H

I-307
H, H
H
CH₃
CH₃
F
H

I-308
H, CH₃
H
CH₃
CH₃
F
H

I-309
H, CH₂CH₃
H
CH₃
CH₃
F
H

I-310
H, CH(CH₃)₂
H
CH₃
CH₃
F
H

I-311
H, C₃H₇
H
CH₃
CH₃
F
H

I-312
H, C(═O)CH₃
H
CH₃
CH₃
F
H

I-313
H, C(═O)CH₂CH₃
H
CH₃
CH₃
F
H

I-314
H, C(═O)C₃H₇
H
CH₃
CH₃
F
H

I-315
H, CH₂CN
H
CH₃
CH₃
F
H

I-316
H, H
CH₃
CH₃
CH₃
F
H

I-317
H, CH₃
CH₃
CH₃
CH₃
F
H

I-318
H, CH₂CH₃
CH₃
CH₃
CH₃
F
H

I-319
H, CH(CH₃)₂
CH₃
CH₃
CH₃
F
H

I-320
H, C₃H₇
CH₃
CH₃
CH₃
F
H

I-321
H, C(═O)CH₃
CH₃
CH₃
CH₃
F
H

I-322
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
H

I-323
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
H

I-324
H, CH₂CN
CH₃
CH₃
CH₃
F
H

I-325
H, H
H
F
CH₃
F
H

I-326
H, CH₃
H
F
CH₃
F
H

I-327
H, CH₂CH₃
H
F
CH₃
F
H

I-328
H, CH(CH₃)₂
H
F
CH₃
F
H

I-329
H, C₃H₇
H
F
CH₃
F
H

I-330
H, C(═O)CH₃
H
F
CH₃
F
H

I-331
H, C(═O)CH₂CH₃
H
F
CH₃
F
H

I-332
H, C(═O)C₃H₇
H
F
CH₃
F
H

I-333
H, CH₂CN
H
F
CH₃
F
H

I-334
H, H
CH₃
F
CH₃
F
H

I-335
H, CH₃
CH₃
F
CH₃
F
H

I-336
H, CH₂CH₃
CH₃
F
CH₃
F
H

I-337
H, CH(CH₃)₂
CH₃
F
CH₃
F
H

I-338
H, C₃H₇
CH₃
F
CH₃
F
H

I-339
H, C(═O)CH₃
CH₃
F
CH₃
F
H

I-340
H, C(═O)CH₂CH₃
CH₃
F
CH₃
F
H

I-341
H, C(═O)C₃H₇
CH₃
F
CH₃
F
H

I-342
H, CH₂CN
CH₃
F
CH₃
F
H

I-343
H, H
H
F
F
H
H

I-344
H, CH₃
H
F
F
H
H

I-345
H, CH₂CH₃
H
F
F
H
H

I-346
H, CH(CH₃)₂
H
F
F
H
H

I-347
H, C₃H₇
H
F
F
H
H

I-348
H, C(═O)CH₃
H
F
F
H
H

I-349
H, C(═O)CH₂CH₃
H
F
F
H
H

I-350
H, C(═O)C₃H₇
H
F
F
H
H

I-351
H, CH₂CN
H
F
F
H
H

I-352
H, H
CH₃
F
F
H
H

I-353
H, CH₃
CH₃
F
F
H
H

I-354
H, CH₂CH₃
CH₃
F
F
H
H

I-355
H, CH(CH₃)₂
CH₃
F
F
H
H

I-356
H, C₃H₇
CH₃
F
F
H
H

I-357
H, C(═O)CH₃
CH₃
F
F
H
H

I-358
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-359
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-360
H, CH₂CN
CH₃
F
F
H
H

I-361
H, H
H
C═O
F
H

I-362
H, CH₃
H
C═O
F
H

I-363
H, CH₂CH₃
H
C═O
F
H

I-364
H, CH(CH₃)₂
H
C═O
F
H

I-365
H, C₃H₇
H
C═O
F
H

I-366
H, C(═O)CH₃
H
C═O
F
H

I-367
H, C(═O)CH₂CH₃
H
C═O
F
H

I-368
H, C(═O)C₃H₇
H
C═O
F
H

I-369
H, CH₂CN
H
C═O
F
H

I-370
H, H
CH₃
C═O
F
H

I-371
H, CH₃
CH₃
C═O
F
H

I-372
H, CH₂CH₃
CH₃
C═O
F
H

I-373
H, CH(CH₃)₂
CH₃
C═O
F
H

I-374
H, C₃H₇
CH₃
C═O
F
H

I-375
H, C(═O)CH₃
CH₃
C═O
F
H

I-376
H, C(═O)CH₂CH₃
CH₃
C═O
F
H

I-377
H, C(═O)C₃H₇
CH₃
C═O
F
H

I-378
H, CH₂CN
CH₃
C═O
F
H

I-379
H, H
H
H
H
CH₃
CH₃

I-380
H, CH₃
H
H
H
CH₃
CH₃

I-381
H, CH₂CH₃
H
H
H
CH₃
CH₃

I-382
H, CH(CH₃)₂
H
H
H
CH₃
CH₃

I-383
H, C₃H₇
H
H
H
CH₃
CH₃

I-384
H, C(═O)CH₃
H
H
H
CH₃
CH₃

I-385
H, C(═O)CH₂CH₃
H
H
H
CH₃
CH₃

I-386
H, C(═O)C₃H₇
H
H
H
CH₃
CH₃

I-387
H, CH₂CN
H
H
H
CH₃
CH₃

I-388
H, H
CH₃
H
H
CH₃
CH₃

I-389
H, CH₃
CH₃
H
H
CH₃
CH₃

I-390
H, CH₂CH₃
CH₃
H
H
CH₃
CH₃

I-391
H, CH(CH₃)₂
CH₃
H
H
CH₃
CH₃

I-392
H, C₃H₇
CH₃
H
H
CH₃
CH₃

I-393
H, C(═O)CH₃
CH₃
H
H
CH₃
CH₃

I-394
H, C(═O)CH₂CH₃
CH₃
H
H
CH₃
CH₃

I-395
H, C(═O)C₃H₇
CH₃
H
H
CH₃
CH₃

I-396
H, CH₂CN
CH₃
H
H
CH₃
CH₃

I-397
H, H
H
CH₃
H
CH₃
CH₃

I-398
H, CH₃
H
CH₃
H
CH₃
CH₃

I-399
H, CH₂CH₃
H
CH₃
H
CH₃
CH₃

I-400
H, CH(CH₃)₂
H
CH₃
H
CH₃
CH₃

I-401
H, C₃H₇
H
CH₃
H
CH₃
CH₃

I-402
H, C(═O)CH₃
H
CH₃
H
CH₃
CH₃

I-403
H, C(═O)CH₂CH₃
H
CH₃
H
CH₃
CH₃

I-404
H, C(═O)C₃H₇
H
CH₃
H
CH₃
CH₃

I-405
H, CH₂CN
H
CH₃
H
CH₃
CH₃

I-406
H, H
CH₃
CH₃
H
CH₃
CH₃

I-407
H, CH₃
CH₃
CH₃
H
CH₃
CH₃

I-408
H, CH₂CH₃
CH₃
CH₃
H
CH₃
CH₃

I-409
H, CH(CH₃)₂
CH₃
CH₃
H
CH₃
CH₃

I-410
H, C₃H₇
CH₃
CH₃
H
CH₃
CH₃

I-411
H, C(═O)CH₃
CH₃
CH₃
H
CH₃
CH₃

I-412
H, C(═O)CH₂CH₃
CH₃
CH₃
H
CH₃
CH₃

I-413
H, C(═O)C₃H₇
CH₃
CH₃
H
CH₃
CH₃

I-414
H, CH₂CN
CH₃
CH₃
H
CH₃
CH₃

I-415
H, H
H
F
H
CH₃
CH₃

I-416
H, CH₃
H
F
H
CH₃
CH₃

I-417
H, CH₂CH₃
H
F
H
CH₃
CH₃

I-418
H, CH(CH₃)₂
H
F
H
CH₃
CH₃

I-419
H, C₃H₇
H
F
H
CH₃
CH₃

I-420
H, C(═O)CH₃
H
F
H
CH₃
CH₃

I-421
H, C(═O)CH₂CH₃
H
F
H
CH₃
CH₃

I-422
H, C(═O)C₃H₇
H
F
H
CH₃
CH₃

I-423
H, CH₂CN
H
F
H
CH₃
CH₃

I-424
H, H
CH₃
F
H
CH₃
CH₃

I-425
H, CH₃
CH₃
F
H
CH₃
CH₃

I-426
H, CH₂CH₃
CH₃
F
H
CH₃
CH₃

I-427
H, CH(CH₃)₂
CH₃
F
H
CH₃
CH₃

I-428
H, C₃H₇
CH₃
F
H
CH₃
CH₃

I-429
H, C(═O)CH₃
CH₃
F
H
CH₃
CH₃

I-430
H, C(═O)CH₂CH₃
CH₃
F
H
CH₃
CH₃

I-431
H, C(═O)C₃H₇
CH₃
F
H
CH₃
CH₃

I-432
H, CH₂CN
CH₃
F
H
CH₃
CH₃

I-433
H, H
H
CH₃
CH₃
CH₃
CH₃

I-434
H, CH₃
H
CH₃
CH₃
CH₃
CH₃

I-435
H, CH₂CH₃
H
CH₃
CH₃
CH₃
CH₃

I-436
H, CH(CH₃)₂
H
CH₃
CH₃
CH₃
CH₃

I-437
H, C₃H₇
H
CH₃
CH₃
CH₃
CH₃

I-438
H, C(═O)CH₃
H
CH₃
CH₃
CH₃
CH₃

I-439
H, C(═O)CH₂CH₃
H
CH₃
CH₃
CH₃
CH₃

I-440
H, C(═O)C₃H₇
H
CH₃
CH₃
CH₃
CH₃

I-441
H, CH₂CN
H
CH₃
CH₃
CH₃
CH₃

I-442
H, H
CH₃
CH₃
CH₃
CH₃
CH₃

I-443
H, CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-444
H, CH₂CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-445
H, CH(CH₃)₂
CH₃
CH₃
CH₃
CH₃
CH₃

I-446
H, C₃H₇
CH₃
CH₃
CH₃
CH₃
CH₃

I-447
H, C(═O)CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-448
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-449
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
CH₃
CH₃

I-450
H, CH₂CN
CH₃
CH₃
CH₃
CH₃
CH₃

I-451
H, H
H
F
CH₃
CH₃
CH₃

I-452
H, CH₃
H
F
CH₃
CH₃
CH₃

I-453
H, CH₂CH₃
H
F
CH₃
CH₃
CH₃

I-454
H, CH(CH₃)₂
H
F
CH₃
CH₃
CH₃

I-455
H, C₃H₇
H
F
CH₃
CH₃
CH₃

I-456
H, C(═O)CH₃
H
F
CH₃
CH₃
CH₃

I-457
H, C(═O)CH₂CH₃
H
F
CH₃
CH₃
CH₃

I-458
H, C(═O)C₃H₇
H
F
CH₃
CH₃
CH₃

I-459
H, CH₂CN
H
F
CH₃
CH₃
CH₃

I-460
H, H
CH₃
F
CH₃
CH₃
CH₃

I-461
H, CH₃
CH₃
F
CH₃
CH₃
CH₃

I-462
H, CH₂CH₃
CH₃
F
CH₃
CH₃
CH₃

I-463
H, CH(CH₃)₂
CH₃
F
CH₃
CH₃
CH₃

I-464
H, C₃H₇
CH₃
F
CH₃
CH₃
CH₃

I-465
H, C(═O)CH₃
CH₃
F
CH₃
CH₃
CH₃

I-466
H, C(═O)CH₂CH₃
CH₃
F
CH₃
CH₃
CH₃

I-467
H, C(═O)C₃H₇
CH₃
F
CH₃
CH₃
CH₃

I-468
H, CH₂CN
CH₃
F
CH₃
CH₃
CH₃

I-469
H, H
H
F
F
H
H

I-470
H, CH₃
H
F
F
H
H

I-471
H, CH₂CH₃
H
F
F
H
H

I-472
H, CH(CH₃)₂
H
F
F
H
H

I-473
H, C₃H₇
H
F
F
H
H

I-474
H, C(═O)CH₃
H
F
F
H
H

I-475
H, C(═O)CH₂CH₃
H
F
F
H
H

I-476
H, C(═O)C₃H₇
H
F
F
H
H

I-477
H, CH₂CN
H
F
F
H
H

I-478
H, H
CH₃
F
F
H
H

I-479
H, CH₃
CH₃
F
F
H
H

I-480
H, CH₂CH₃
CH₃
F
F
H
H

I-481
H, CH(CH₃)₂
CH₃
F
F
H
H

I-482
H, C₃H₇
CH₃
F
F
H
H

I-483
H, C(═O)CH₃
CH₃
F
F
H
H

I-484
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-485
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-486
H, CH₂CN
CH₃
F
F
H
H

I-487
H, H
H
C═O
CH₃
CH₃

I-488
H, CH₃
H
C═O
CH₃
CH₃

I-489
H, CH₂CH₃
H
C═O
CH₃
CH₃

I-490
H, CH(CH₃)₂
H
C═O
CH₃
CH₃

I-491
H, C₃H₇
H
C═O
CH₃
CH₃

I-492
H, C(═O)CH₃
H
C═O
CH₃
CH₃

I-493
H, C(═O)CH₂CH₃
H
C═O
CH₃
CH₃

I-494
H, C(═O)C₃H₇
H
C═O
CH₃
CH₃

I-495
H, CH₂CN
H
C═O
CH₃
CH₃

I-496
H, H
CH₃
C═O
CH₃
CH₃

I-497
H, CH₃
CH₃
C═O
CH₃
CH₃

I-498
H, CH₂CH₃
CH₃
C═O
CH₃
CH₃

I-499
H, CH(CH₃)₂
CH₃
C═O
CH₃
CH₃

I-500
H, C₃H₇
CH₃
C═O
CH₃
CH₃

I-501
H, C(═O)CH₃
CH₃
C═O
CH₃
CH₃

I-502
H, C(═O)CH₂CH₃
CH₃
C═O
CH₃
CH₃

I-503
H, C(═O)C₃H₇
CH₃
C═O
CH₃
CH₃

I-504
H, CH₂CN
CH₃
C═O
CH₃
CH₃

I-505
H, H
H
H
H
F
CH₃

I-506
H, CH₃
H
H
H
F
CH₃

I-507
H, CH₂CH₃
H
H
H
F
CH₃

I-508
H, CH(CH₃)₂
H
H
H
F
CH₃

I-509
H, C₃H₇
H
H
H
F
CH₃

I-510
H, C(═O)CH₃
H
H
H
F
CH₃

I-511
H, C(═O)CH₂CH₃
H
H
H
F
CH₃

I-512
H, C(═O)C₃H₇
H
H
H
F
CH₃

I-513
H, CH₂CN
H
H
H
F
CH₃

I-514
H, H
CH₃
H
H
F
CH₃

I-515
H, CH₃
CH₃
H
H
F
CH₃

I-516
H, CH₂CH₃
CH₃
H
H
F
CH₃

I-517
H, CH(CH₃)₂
CH₃
H
H
F
CH₃

I-518
H, C₃H₇
CH₃
H
H
F
CH₃

I-519
H, C(═O)CH₃
CH₃
H
H
F
CH₃

I-520
H, C(═O)CH₂CH₃
CH₃
H
H
F
CH₃

I-521
H, C(═O)C₃H₇
CH₃
H
H
F
CH₃

I-522
H, CH₂CN
CH₃
H
H
F
CH₃

I-523
H, H
H
CH₃
H
F
CH₃

I-524
H, CH₃
H
CH₃
H
F
CH₃

I-525
H, CH₂CH₃
H
CH₃
H
F
CH₃

I-526
H, CH(CH₃)₂
H
CH₃
H
F
CH₃

I-527
H, C₃H₇
H
CH₃
H
F
CH₃

I-528
H, C(═O)CH₃
H
CH₃
H
F
CH₃

I-529
H, C(═O)CH₂CH₃
H
CH₃
H
F
CH₃

I-530
H, C(═O)C₃H₇
H
CH₃
H
F
CH₃

I-531
H, CH₂CN
H
CH₃
H
F
CH₃

I-532
H, H
CH₃
CH₃
H
F
CH₃

I-533
H, CH₃
CH₃
CH₃
H
F
CH₃

I-534
H, CH₂CH₃
CH₃
CH₃
H
F
CH₃

I-535
H, CH(CH₃)₂
CH₃
CH₃
H
F
CH₃

I-536
H, C₃H₇
CH₃
CH₃
H
F
CH₃

I-537
H, C(═O)CH₃
CH₃
CH₃
H
F
CH₃

I-538
H, C(═O)CH₂CH₃
CH₃
CH₃
H
F
CH₃

I-539
H, C(═O)C₃H₇
CH₃
CH₃
H
F
CH₃

I-540
H, CH₂CN
CH₃
CH₃
H
F
CH₃

I-541
H, H
H
F
H
F
CH₃

I-542
H, CH₃
H
F
H
F
CH₃

I-543
H, CH₂CH₃
H
F
H
F
CH₃

I-544
H, CH(CH₃)₂
H
F
H
F
CH₃

I-545
H, C₃H₇
H
F
H
F
CH₃

I-546
H, C(═O)CH₃
H
F
H
F
CH₃

I-547
H, C(═O)CH₂CH₃
H
F
H
F
CH₃

I-548
H, C(═O)C₃H₇
H
F
H
F
CH₃

I-549
H, CH₂CN
H
F
H
F
CH₃

I-550
H, H
CH₃
F
H
F
CH₃

I-551
H, CH₃
CH₃
F
H
F
CH₃

I-552
H, CH₂CH₃
CH₃
F
H
F
CH₃

I-553
H, CH(CH₃)₂
CH₃
F
H
F
CH₃

I-554
H, C₃H₇
CH₃
F
H
F
CH₃

I-555
H, C(═O)CH₃
CH₃
F
H
F
CH₃

I-556
H, C(═O)CH₂CH₃
CH₃
F
H
F
CH₃

I-557
H, C(═O)C₃H₇
CH₃
F
H
F
CH₃

I-558
H, CH₂CN
CH₃
F
H
F
CH₃

I-559
H, H
H
CH₃
CH₃
F
CH₃

I-560
H, CH₃
H
CH₃
CH₃
F
CH₃

I-561
H, CH₂CH₃
H
CH₃
CH₃
F
CH₃

I-562
H, CH(CH₃)₂
H
CH₃
CH₃
F
CH₃

I-563
H, C₃H₇
H
CH₃
CH₃
F
CH₃

I-564
H, C(═O)CH₃
H
CH₃
CH₃
F
CH₃

I-565
H, C(═O)CH₂CH₃
H
CH₃
CH₃
F
CH₃

I-566
H, C(═O)C₃H₇
H
CH₃
CH₃
F
CH₃

I-567
H, CH₂CN
H
CH₃
CH₃
F
CH₃

I-568
H, H
CH₃
CH₃
CH₃
F
CH₃

I-569
H, CH₃
CH₃
CH₃
CH₃
F
CH₃

I-570
H, CH₂CH₃
CH₃
CH₃
CH₃
F
CH₃

I-571
H, CH(CH₃)₂
CH₃
CH₃
CH₃
F
CH₃

I-572
H, C₃H₇
CH₃
CH₃
CH₃
F
CH₃

I-573
H, C(═O)CH₃
CH₃
CH₃
CH₃
F
CH₃

I-574
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
CH₃

I-575
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
CH₃

I-576
H, CH₂CN
CH₃
CH₃
CH₃
F
CH₃

I-577
H, H
H
F
CH₃
F
CH₃

I-578
H, CH₃
H
F
CH₃
F
CH₃

I-579
H, CH₂CH₃
H
F
CH₃
F
CH₃

I-580
H, CH(CH₃)₂
H
F
CH₃
F
CH₃

I-581
H, C₃H₇
H
F
CH₃
F
CH₃

I-582
H, C(═O)CH₃
H
F
CH₃
F
CH₃

I-583
H, C(═O)CH₂CH₃
H
F
CH₃
F
CH₃

I-584
H, C(═O)C₃H₇
H
F
CH₃
F
CH₃

I-585
H, CH₂CN
H
F
CH₃
F
CH₃

I-586
H, H
CH₃
F
CH₃
F
CH₃

I-587
H, CH₃
CH₃
F
CH₃
F
CH₃

I-588
H, CH₂CH₃
CH₃
F
CH₃
F
CH₃

I-589
H, CH(CH₃)₂
CH₃
F
CH₃
F
CH₃

I-590
H, C₃H₇
CH₃
F
CH₃
F
CH₃

I-591
H, C(═O)CH₃
CH₃
F
CH₃
F
CH₃

I-592
H, C(═O)CH₂CH₃
CH₃
F
CH₃
F
CH₃

I-593
H, C(═O)C₃H₇
CH₃
F
CH₃
F
CH₃

I-594
H, CH₂CN
CH₃
F
CH₃
F
CH₃

I-595
H, H
H
F
F
H
H

I-596
H, CH₃
H
F
F
H
H

I-597
H, CH₂CH₃
H
F
F
H
H

I-598
H, CH(CH₃)₂
H
F
F
H
H

I-599
H, C₃H₇
H
F
F
H
H

I-600
H, C(═O)CH₃
H
F
F
H
H

I-601
H, C(═O)CH₂CH₃
H
F
F
H
H

I-602
H, C(═O)C₃H₇
H
F
F
H
H

I-603
H, CH₂CN
H
F
F
H
H

I-604
H, H
CH₃
F
F
H
H

I-605
H, CH₃
CH₃
F
F
H
H

I-606
H, CH₂CH₃
CH₃
F
F
H
H

I-607
H, CH(CH₃)₂
CH₃
F
F
H
H

I-608
H, C₃H₇
CH₃
F
F
H
H

I-609
H, C(═O)CH₃
CH₃
F
F
H
H

I-610
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-611
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-612
H, CH₂CN
CH₃
F
F
H
H

I-613
H, H
H
C═O
F
CH₃

I-614
H, CH₃
H
C═O
F
CH₃

I-615
H, CH₂CH₃
H
C═O
F
CH₃

I-616
H, CH(CH₃)₂
H
C═O
F
CH₃

I-617
H, C₃H₇
H
C═O
F
CH₃

I-618
H, C(═O)CH₃
H
C═O
F
CH₃

I-619
H, C(═O)CH₂CH₃
H
C═O
F
CH₃

I-620
H, C(═O)C₃H₇
H
C═O
F
CH₃

I-621
H, CH₂CN
H
C═O
F
CH₃

I-622
H, H
CH₃
C═O
F
CH₃

I-623
H, CH₃
CH₃
C═O
F
CH₃

I-624
H, CH₂CH₃
CH₃
C═O
F
CH₃

I-625
H, CH(CH₃)₂
CH₃
C═O
F
CH₃

I-626
H, C₃H₇
CH₃
C═O
F
CH₃

I-627
H, C(═O)CH₃
CH₃
C═O
F
CH₃

I-628
H, C(═O)CH₂CH₃
CH₃
C═O
F
CH₃

I-629
H, C(═O)C₃H₇
CH₃
C═O
F
CH₃

I-630
H, CH₂CN
CH₃
C═O
F
CH₃

I-631
H, H
H
H
H
F
F

I-632
H, CH₃
H
H
H
F
F

I-633
H, CH₂CH₃
H
H
H
F
F

I-634
H, CH(CH₃)₂
H
H
H
F
F

I-635
H, C₃H₇
H
H
H
F
F

I-636
H, C(═O)CH₃
H
H
H
F
F

I-637
H, C(═O)CH₂CH₃
H
H
H
F
F

I-638
H, C(═O)C₃H₇
H
H
H
F
F

I-639
H, CH₂CN
H
H
H
F
F

I-640
H, H
CH₃
H
H
F
F

I-641
H, CH₃
CH₃
H
H
F
F

I-642
H, CH₂CH₃
CH₃
H
H
F
F

I-643
H, CH(CH₃)₂
CH₃
H
H
F
F

I-644
H, C₃H₇
CH₃
H
H
F
F

I-645
H, C(═O)CH₃
CH₃
H
H
F
F

I-646
H, C(═O)CH₂CH₃
CH₃
H
H
F
F

I-647
H, C(═O)C₃H₇
CH₃
H
H
F
F

I-648
H, CH₂CN
CH₃
H
H
F
F

I-649
H, H
H
CH₃
H
F
F

I-650
H, CH₃
H
CH₃
H
F
F

I-651
H, CH₂CH₃
H
CH₃
H
F
F

I-652
H, CH(CH₃)₂
H
CH₃
H
F
F

I-653
H, C₃H₇
H
CH₃
H
F
F

I-654
H, C(═O)CH₃
H
CH₃
H
F
F

I-655
H, C(═O)CH₂CH₃
H
CH₃
H
F
F

I-656
H, C(═O)C₃H₇
H
CH₃
H
F
F

I-657
H, CH₂CN
H
CH₃
H
F
F

I-658
H, H
CH₃
CH₃
H
F
F

I-659
H, CH₃
CH₃
CH₃
H
F
F

I-660
H, CH₂CH₃
CH₃
CH₃
H
F
F

I-661
H, CH(CH₃)₂
CH₃
CH₃
H
F
F

I-662
H, C₃H₇
CH₃
CH₃
H
F
F

I-663
H, C(═O)CH₃
CH₃
CH₃
H
F
F

I-664
H, C(═O)CH₂CH₃
CH₃
CH₃
H
F
F

I-665
H, C(═O)C₃H₇
CH₃
CH₃
H
F
F

I-666
H, CH₂CN
CH₃
CH₃
H
F
F

I-667
H, H
H
F
H
F
F

I-668
H, CH₃
H
F
H
F
F

I-669
H, CH₂CH₃
H
F
H
F
F

I-670
H, CH(CH₃)₂
H
F
H
F
F

I-671
H, C₃H₇
H
F
H
F
F

I-672
H, C(═O)CH₃
H
F
H
F
F

I-673
H, C(═O)CH₂CH₃
H
F
H
F
F

I-674
H, C(═O)C₃H₇
H
F
H
F
F

I-675
H, CH₂CN
H
F
H
F
F

I-676
H, H
CH₃
F
H
F
F

I-677
H, CH₃
CH₃
F
H
F
F

I-678
H, CH₂CH₃
CH₃
F
H
F
F

I-679
H, CH(CH₃)₂
CH₃
F
H
F
F

I-680
H, C₃H₇
CH₃
F
H
F
F

I-681
H, C(═O)CH₃
CH₃
F
H
F
F

I-682
H, C(═O)CH₂CH₃
CH₃
F
H
F
F

I-683
H, C(═O)C₃H₇
CH₃
F
H
F
F

I-684
H, CH₂CN
CH₃
F
H
F
F

I-685
H, H
H
CH₃
CH₃
F
F

I-686
H, CH₃
H
CH₃
CH₃
F
F

I-687
H, CH₂CH₃
H
CH₃
CH₃
F
F

I-688
H, CH(CH₃)₂
H
CH₃
CH₃
F
F

I-689
H, C₃H₇
H
CH₃
CH₃
F
F

I-690
H, C(═O)CH₃
H
CH₃
CH₃
F
F

I-691
H, C(═O)CH₂CH₃
H
CH₃
CH₃
F
F

I-692
H, C(═O)C₃H₇
H
CH₃
CH₃
F
F

I-693
H, CH₂CN
H
CH₃
CH₃
F
F

I-694
H, H
CH₃
CH₃
CH₃
F
F

I-695
H, CH₃
CH₃
CH₃
CH₃
F
F

I-696
H, CH₂CH₃
CH₃
CH₃
CH₃
F
F

I-697
H, CH(CH₃)₂
CH₃
CH₃
CH₃
F
F

I-698
H, C₃H₇
CH₃
CH₃
CH₃
F
F

I-699
H, C(═O)CH₃
CH₃
CH₃
CH₃
F
F

I-700
H, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
F

I-701
H, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
F

I-702
H, CH₂CN
CH₃
CH₃
CH₃
F
F

I-703
H, H
H
F
CH₃
F
F

I-704
H, CH₃
H
F
CH₃
F
F

I-705
H, CH₂CH₃
H
F
CH₃
F
F

I-706
H, CH(CH₃)₂
H
F
CH₃
F
F

I-707
H, C₃H₇
H
F
CH₃
F
F

I-708
H, C(═O)CH₃
H
F
CH₃
F
F

I-709
H, C(═O)CH₂CH₃
H
F
CH₃
F
F

I-710
H, C(═O)C₃H₇
H
F
CH₃
F
F

I-711
H, CH₂CN
H
F
CH₃
F
F

I-712
H, H
CH₃
F
CH₃
F
F

I-713
H, CH₃
CH₃
F
CH₃
F
F

I-714
H, CH₂CH₃
CH₃
F
CH₃
F
F

I-715
H, CH(CH₃)₂
CH₃
F
CH₃
F
F

I-716
H, C₃H₇
CH₃
F
CH₃
F
F

I-717
H, C(═O)CH₃
CH₃
F
CH₃
F
F

I-718
H, C(═O)CH₂CH₃
CH₃
F
CH₃
F
F

I-719
H, C(═O)C₃H₇
CH₃
F
CH₃
F
F

I-720
H, CH₂CN
CH₃
F
CH₃
F
F

I-721
H, H
H
F
F
H
H

I-722
H, CH₃
H
F
F
H
H

I-723
H, CH₂CH₃
H
F
F
H
H

I-724
H, CH(CH₃)₂
H
F
F
H
H

I-725
H, C₃H₇
H
F
F
H
H

I-726
H, C(═O)CH₃
H
F
F
H
H

I-727
H, C(═O)CH₂CH₃
H
F
F
H
H

I-728
H, C(═O)C₃H₇
H
F
F
H
H

I-729
H, CH₂CN
H
F
F
H
H

I-730
H, H
CH₃
F
F
H
H

I-731
H, CH₃
CH₃
F
F
H
H

I-732
H, CH₂CH₃
CH₃
F
F
H
H

I-733
H, CH(CH₃)₂
CH₃
F
F
H
H

I-734
H, C₃H₇
CH₃
F
F
H
H

I-735
H, C(═O)CH₃
CH₃
F
F
H
H

I-736
H, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-737
H, C(═O)C₃H₇
CH₃
F
F
H
H

I-738
H, CH₂CN
CH₃
F
F
H
H

I-739
H, H
H
C═O
F
F

I-740
H, CH₃
H
C═O
F
F

I-741
H, CH₂CH₃
H
C═O
F
F

I-742
H, CH(CH₃)₂
H
C═O
F
F

I-743
H, C₃H₇
H
C═O
F
F

I-744
H, C(═O)CH₃
H
C═O
F
F

I-745
H, C(═O)CH₂CH₃
H
C═O
F
F

I-746
H, C(═O)C₃H₇
H
C═O
F
F

I-747
H, CH₂CN
H
C═O
F
F

I-748
H, H
CH₃
C═O
F
F

I-749
H, CH₃
CH₃
C═O
F
F

I-750
H, CH₂CH₃
CH₃
C═O
F
F

I-751
H, CH(CH₃)₂
CH₃
C═O
F
F

I-752
H, C₃H₇
CH₃
C═O
F
F

I-753
H, C(═O)CH₃
CH₃
C═O
F
F

I-754
H, C(═O)CH₂CH₃
CH₃
C═O
F
F

I-755
H, C(═O)C₃H₇
CH₃
C═O
F
F

I-756
H, CH₂CN
CH₃
C═O
F
F

I-757
CH₃, CH₃
H
H
H
H
H

I-758
CH₃, CH₂CH₃
H
H
H
H
H

I-759
CH₃, CH(CH₃)₂
H
H
H
H
H

I-760
CH₃, C₃H₇
H
H
H
H
H

I-761
CH₃, C(═O)CH₃
H
H
H
H
H

I-762
CH₃, C(═O)CH₂CH₃
H
H
H
H
H

I-763
CH₃, C(═O)C₃H₇
H
H
H
H
H

I-764
CH₃, CH₂CN
H
H
H
H
H

I-765
CH₃, H
CH₃
H
H
H
H

I-766
CH₃, CH₃
CH₃
H
H
H
H

I-767
CH₃, CH₂CH₃
CH₃
H
H
H
H

I-768
CH₃, CH(CH₃)₂
CH₃
H
H
H
H

I-769
CH₃, C₃H₇
CH₃
H
H
H
H

I-770
CH₃, C(═O)CH₃
CH₃
H
H
H
H

I-771
CH₃, C(═O)CH₂CH₃
CH₃
H
H
H
H

I-772
CH₃, C(═O)C₃H₇
CH₃
H
H
H
H

I-773
CH₃, CH₂CN
CH₃
H
H
H
H

I-774
CH₃, CH₃
H
CH₃
H
H
H

I-775
CH₃, CH₂CH₃
H
CH₃
H
H
H

I-776
CH₃, CH(CH₃)₂
H
CH₃
H
H
H

I-777
CH₃, C₃H₇
H
CH₃
H
H
H

I-778
CH₃, C(═O)CH₃
H
CH₃
H
H
H

I-779
CH₃, C(═O)CH₂CH₃
H
CH₃
H
H
H

I-780
CH₃, C(═O)C₃H₇
H
CH₃
H
H
H

I-781
CH₃, CH₂CN
H
CH₃
H
H
H

I-782
CH₃, CH₃
CH₃
CH₃
H
H
H

I-783
CH₃, CH₂CH₃
CH₃
CH₃
H
H
H

I-784
CH₃, CH(CH₃)₂
CH₃
CH₃
H
H
H

I-785
CH₃, C₃H₇
CH₃
CH₃
H
H
H

I-786
CH₃, C(═O)CH₃
CH₃
CH₃
H
H
H

I-787
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
H
H

I-788
CH₃, C(═O)C₃H₇
CH₃
CH₃
H
H
H

I-789
CH₃, CH₂CN
CH₃
CH₃
H
H
H

I-790
CH₃, CH₃
H
F
H
H
H

I-791
CH₃, CH₂CH₃
H
F
H
H
H

I-792
CH₃, CH(CH₃)₂
H
F
H
H
H

I-793
CH₃, C₃H₇
H
F
H
H
H

I-794
CH₃, C(═O)CH₃
H
F
H
H
H

I-795
CH₃, C(═O)CH₂CH₃
H
F
H
H
H

I-796
CH₃, C(═O)C₃H₇
H
F
H
H
H

I-797
CH₃, CH₂CN
H
F
H
H
H

I-798
CH₃, CH₃
CH₃
F
H
H
H

I-799
CH₃, CH₂CH₃
CH₃
F
H
H
H

I-800
CH₃, CH(CH₃)₂
CH₃
F
H
H
H

I-801
CH₃, C₃H₇
CH₃
F
H
H
H

I-802
CH₃, C(═O)CH₃
CH₃
F
H
H
H

I-803
CH₃, C(═O)CH₂CH₃
CH₃
F
H
H
H

I-804
CH₃, C(═O)C₃H₇
CH₃
F
H
H
H

I-805
CH₃, CH₂CN
CH₃
F
H
H
H

I-806
CH₃, CH₃
H
CH₃
CH₃
H
H

I-807
CH₃, CH₂CH₃
H
CH₃
CH₃
H
H

I-808
CH₃, CH(CH₃)₂
H
CH₃
CH₃
H
H

I-809
CH₃, C₃H₇
H
CH₃
CH₃
H
H

I-810
CH₃, C(═O)CH₃
H
CH₃
CH₃
H
H

I-811
CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
H
H

I-812
CH₃, C(═O)C₃H₇
H
CH₃
CH₃
H
H

I-813
CH₃, CH₂CN
H
CH₃
CH₃
H
H

I-814
CH₃, CH₃
CH₃
CH₃
CH₃
H
H

I-815
CH₃, CH₂CH₃
CH₃
CH₃
CH₃
H
H

I-816
CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
H
H

I-817
CH₃, C₃H₇
CH₃
CH₃
CH₃
H
H

I-818
CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
H
H

I-819
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
H
H

I-820
CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
H
H

I-821
CH₃, CH₂CN
CH₃
CH₃
CH₃
H
H

I-822
CH₃, CH₃
H
F
CH₃
H
H

I-823
CH₃, CH₂CH₃
H
F
CH₃
H
H

I-824
CH₃, CH(CH₃)₂
H
F
CH₃
H
H

I-825
CH₃, C₃H₇
H
F
CH₃
H
H

I-826
CH₃, C(═O)CH₃
H
F
CH₃
H
H

I-827
CH₃, C(═O)CH₂CH₃
H
F
CH₃
H
H

I-828
CH₃, C(═O)C₃H₇
H
F
CH₃
H
H

I-829
CH₃, CH₂CN
H
F
CH₃
H
H

I-830
CH₃, CH₃
CH₃
F
CH₃
H
H

I-831
CH₃, CH₂CH₃
CH₃
F
CH₃
H
H

I-832
CH₃, CH(CH₃)₂
CH₃
F
CH₃
H
H

I-833
CH₃, C₃H₇
CH₃
F
CH₃
H
H

I-834
CH₃, C(═O)CH₃
CH₃
F
CH₃
H
H

I-835
CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
H
H

I-836
CH₃, C(═O)C₃H₇
CH₃
F
CH₃
H
H

I-837
CH₃, CH₂CN
CH₃
F
CH₃
H
H

I-838
CH₃, CH₃
H
F
F
H
H

I-839
CH₃, CH₂CH₃
H
F
F
H
H

I-840
CH₃, CH(CH₃)₂
H
F
F
H
H

I-841
CH₃, C₃H₇
H
F
F
H
H

I-842
CH₃, C(═O)CH₃
H
F
F
H
H

I-843
CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-844
CH₃, C(═O)C₃H₇
H
F
F
H
H

I-845
CH₃, CH₂CN
H
F
F
H
H

I-846
CH₃, CH₃
CH₃
F
F
H
H

I-847
CH₃, CH₂CH₃
CH₃
F
F
H
H

I-848
CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-849
CH₃, C₃H₇
CH₃
F
F
H
H

I-850
CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-851
CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-852
CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-853
CH₃, CH₂CN
CH₃
F
F
H
H

I-854
CH₃, CH₃
H
C═O
H
H

I-855
CH₃, CH₂CH₃
H
C═O
H
H

I-856
CH₃, CH(CH₃)₂
H
C═O
H
H

I-857
CH₃, C₃H₇
H
C═O
H
H

I-858
CH₃, C(═O)CH₃
H
C═O
H
H

I-859
CH₃, C(═O)CH₂CH₃
H
C═O
H
H

I-860
CH₃, C(═O)C₃H₇
H
C═O
H
H

I-861
CH₃, CH₂CN
H
C═O
H
H

I-862
CH₃, CH₃
CH₃
C═O
H
H

I-863
CH₃, CH₂CH₃
CH₃
C═O
H
H

I-864
CH₃, CH(CH₃)₂
CH₃
C═O
H
H

I-865
CH₃, C₃H₇
CH₃
C═O
H
H

I-866
CH₃, C(═O)CH₃
CH₃
C═O
H
H

I-867
CH₃, C(═O)CH₂CH₃
CH₃
C═O
H
H

I-868
CH₃, C(═O)C₃H₇
CH₃
C═O
H
H

I-869
CH₃, CH₂CN
CH₃
C═O
H
H

I-870
CH₃, CH₃
H
H
H
CH₃
H

I-871
CH₃, CH₂CH₃
H
H
H
CH₃
H

I-872
CH₃, CH(CH₃)₂
H
H
H
CH₃
H

I-873
CH₃, C₃H₇
H
H
H
CH₃
H

I-874
CH₃, C(═O)CH₃
H
H
H
CH₃
H

I-875
CH₃, C(═O)CH₂CH₃
H
H
H
CH₃
H

I-876
CH₃, C(═O)C₃H₇
H
H
H
CH₃
H

I-877
CH₃, CH₂CN
H
H
H
CH₃
H

I-878
CH₃, CH₃
CH₃
H
H
CH₃
H

I-879
CH₃, CH₂CH₃
CH₃
H
H
CH₃
H

I-880
CH₃, CH(CH₃)₂
CH₃
H
H
CH₃
H

I-881
CH₃, C₃H₇
CH₃
H
H
CH₃
H

I-882
CH₃, C(═O)CH₃
CH₃
H
H
CH₃
H

I-883
CH₃, C(═O)CH₂CH₃
CH₃
H
H
CH₃
H

I-884
CH₃, C(═O)C₃H₇
CH₃
H
H
CH₃
H

I-885
CH₃, CH₂CN
CH₃
H
H
CH₃
H

I-886
CH₃, CH₃
H
CH₃
H
CH₃
H

I-887
CH₃, CH₂CH₃
H
CH₃
H
CH₃
H

I-888
CH₃, CH(CH₃)₂
H
CH₃
H
CH₃
H

I-889
CH₃, C₃H₇
H
CH₃
H
CH₃
H

I-890
CH₃, C(═O)CH₃
H
CH₃
H
CH₃
H

I-891
CH₃, C(═O)CH₂CH₃
H
CH₃
H
CH₃
H

I-892
CH₃, C(═O)C₃H₇
H
CH₃
H
CH₃
H

I-893
CH₃, CH₂CN
H
CH₃
H
CH₃
H

I-894
CH₃, CH₃
CH₃
CH₃
H
CH₃
H

I-895
CH₃, CH₂CH₃
CH₃
CH₃
H
CH₃
H

I-896
CH₃, CH(CH₃)₂
CH₃
CH₃
H
CH₃
H

I-897
CH₃, C₃H₇
CH₃
CH₃
H
CH₃
H

I-898
CH₃, C(═O)CH₃
CH₃
CH₃
H
CH₃
H

I-899
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
CH₃
H

I-900
CH₃, C(═O)C₃H₇
CH₃
CH₃
H
CH₃
H

I-901
CH₃, CH₂CN
CH₃
CH₃
H
CH₃
H

I-902
CH₃, CH₃
H
F
H
CH₃
H

I-903
CH₃, CH₂CH₃
H
F
H
CH₃
H

I-904
CH₃, CH(CH₃)₂
H
F
H
CH₃
H

I-905
CH₃, C₃H₇
H
F
H
CH₃
H

I-906
CH₃, C(═O)CH₃
H
F
H
CH₃
H

I-907
CH₃, C(═O)CH₂CH₃
H
F
H
CH₃
H

I-908
CH₃, C(═O)C₃H₇
H
F
H
CH₃
H

I-909
CH₃, CH₂CN
H
F
H
CH₃
H

I-910
CH₃, CH₃
CH₃
F
H
CH₃
H

I-911
CH₃, CH₂CH₃
CH₃
F
H
CH₃
H

I-912
CH₃, CH(CH₃)₂
CH₃
F
H
CH₃
H

I-913
CH₃, C₃H₇
CH₃
F
H
CH₃
H

I-914
CH₃, C(═O)CH₃
CH₃
F
H
CH₃
H

I-915
CH₃, C(═O)CH₂CH₃
CH₃
F
H
CH₃
H

I-916
CH₃, C(═O)C₃H₇
CH₃
F
H
CH₃
H

I-917
CH₃, CH₂CN
CH₃
F
H
CH₃
H

I-918
CH₃, CH₃
H
CH₃
CH₃
CH₃
H

I-919
CH₃, CH₂CH₃
H
CH₃
CH₃
CH₃
H

I-920
CH₃, CH(CH₃)₂
H
CH₃
CH₃
CH₃
H

I-921
CH₃, C₃H₇
H
CH₃
CH₃
CH₃
H

I-922
CH₃, C(═O)CH₃
H
CH₃
CH₃
CH₃
H

I-923
CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
CH₃
H

I-924
CH₃, C(═O)C₃H₇
H
CH₃
CH₃
CH₃
H

I-925
CH₃, CH₂CN
H
CH₃
CH₃
CH₃
H

I-926
CH₃, CH₃
CH₃
CH₃
CH₃
CH₃
H

I-927
CH₃, CH₂CH₃
CH₃
CH₃
CH₃
CH₃
H

I-928
CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
CH₃
H

I-929
CH₃, C₃H₇
CH₃
CH₃
CH₃
CH₃
H

I-930
CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
CH₃
H

I-931
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
CH₃
H

I-932
CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
CH₃
H

I-933
CH₃, CH₂CN
CH₃
CH₃
CH₃
CH₃
H

I-934
CH₃, CH₃
H
F
CH₃
CH₃
H

I-935
CH₃, CH₂CH₃
H
F
CH₃
CH₃
H

I-936
CH₃, CH(CH₃)₂
H
F
CH₃
CH₃
H

I-937
CH₃, C₃H₇
H
F
CH₃
CH₃
H

I-938
CH₃, C(═O)CH₃
H
F
CH₃
CH₃
H

I-939
CH₃, C(═O)CH₂CH₃
H
F
CH₃
CH₃
H

I-940
CH₃, C(═O)C₃H₇
H
F
CH₃
CH₃
H

I-941
CH₃, CH₂CN
H
F
CH₃
CH₃
H

I-942
CH₃, CH₃
CH₃
F
CH₃
CH₃
H

I-943
CH₃, CH₂CH₃
CH₃
F
CH₃
CH₃
H

I-944
CH₃, CH(CH₃)₂
CH₃
F
CH₃
CH₃
H

I-945
CH₃, C₃H₇
CH₃
F
CH₃
CH₃
H

I-946
CH₃, C(═O)CH₃
CH₃
F
CH₃
CH₃
H

I-947
CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
CH₃
H

I-948
CH₃, C(═O)C₃H₇
CH₃
F
CH₃
CH₃
H

I-949
CH₃, CH₂CN
CH₃
F
CH₃
CH₃
H

I-950
CH₃, CH₃
H
F
F
H
H

I-951
CH₃, CH₂CH₃
H
F
F
H
H

I-952
CH₃, CH(CH₃)₂
H
F
F
H
H

I-953
CH₃, C₃H₇
H
F
F
H
H

I-954
CH₃, C(═O)CH₃
H
F
F
H
H

I-955
CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-956
CH₃, C(═O)C₃H₇
H
F
F
H
H

I-957
CH₃, CH₂CN
H
F
F
H
H

I-958
CH₃, CH₃
CH₃
F
F
H
H

I-959
CH₃, CH₂CH₃
CH₃
F
F
H
H

I-960
CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-961
CH₃, C₃H₇
CH₃
F
F
H
H

I-962
CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-963
CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-964
CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-965
CH₃, CH₂CN
CH₃
F
F
H
H

I-966
CH₃, CH₃
H
C═O
CH₃
H

I-967
CH₃, CH₂CH₃
H
C═O
CH₃
H

I-968
CH₃, CH(CH₃)₂
H
C═O
CH₃
H

I-969
CH₃, C₃H₇
H
C═O
CH₃
H

I-970
CH₃, C(═O)CH₃
H
C═O
CH₃
H

I-971
CH₃, C(═O)CH₂CH₃
H
C═O
CH₃
H

I-972
CH₃, C(═O)C₃H₇
H
C═O
CH₃
H

I-973
CH₃, CH₂CN
H
C═O
CH₃
H

I-974
CH₃, CH₃
CH₃
C═O
CH₃
H

I-975
CH₃, CH₂CH₃
CH₃
C═O
CH₃
H

I-976
CH₃, CH(CH₃)₂
CH₃
C═O
CH₃
H

I-977
CH₃, C₃H₇
CH₃
C═O
CH₃
H

I-978
CH₃, C(═O)CH₃
CH₃
C═O
CH₃
H

I-979
CH₃, C(═O)CH₂CH₃
CH₃
C═O
CH₃
H

I-980
CH₃, C(═O)C₃H₇
CH₃
C═O
CH₃
H

I-981
CH₃, CH₂CN
CH₃
C═O
CH₃
H

I-982
CH₃, CH₃
H
H
H
F
H

I-983
CH₃, CH₂CH₃
H
H
H
F
H

I-984
CH₃, CH(CH₃)₂
H
H
H
F
H

I-985
CH₃, C₃H₇
H
H
H
F
H

I-986
CH₃, C(═O)CH₃
H
H
H
F
H

I-987
CH₃, C(═O)CH₂CH₃
H
H
H
F
H

I-988
CH₃, C(═O)C₃H₇
H
H
H
F
H

I-989
CH₃, CH₂CN
H
H
H
F
H

I-990
CH₃, CH₃
CH₃
H
H
F
H

I-991
CH₃, CH₂CH₃
CH₃
H
H
F
H

I-992
CH₃, CH(CH₃)₂
CH₃
H
H
F
H

I-993
CH₃, C₃H₇
CH₃
H
H
F
H

I-994
CH₃, C(═O)CH₃
CH₃
H
H
F
H

I-995
CH₃, C(═O)CH₂CH₃
CH₃
H
H
F
H

I-996
CH₃, C(═O)C₃H₇
CH₃
H
H
F
H

I-997
CH₃, CH₂CN
CH₃
H
H
F
H

I-998
CH₃, CH₃
H
CH₃
H
F
H

I-999
CH₃, CH₂CH₃
H
CH₃
H
F
H

I-1000
CH₃, CH(CH₃)₂
H
CH₃
H
F
H

I-1001
CH₃, C₃H₇
H
CH₃
H
F
H

I-1002
CH₃, C(═O)CH₃
H
CH₃
H
F
H

I-1003
CH₃, C(═O)CH₂CH₃
H
CH₃
H
F
H

I-1004
CH₃, C(═O)C₃H₇
H
CH₃
H
F
H

I-1005
CH₃, CH₂CN
H
CH₃
H
F
H

I-1006
CH₃, CH₃
CH₃
CH₃
H
F
H

I-1007
CH₃, CH₂CH₃
CH₃
CH₃
H
F
H

I-1008
CH₃, CH(CH₃)₂
CH₃
CH₃
H
F
H

I-1009
CH₃, C₃H₇
CH₃
CH₃
H
F
H

I-1010
CH₃, C(═O)CH₃
CH₃
CH₃
H
F
H

I-1011
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
F
H

I-1012
CH₃, C(═O)C₃H₇
CH₃
CH₃
H
F
H

I-1013
CH₃, CH₂CN
CH₃
CH₃
H
F
H

I-1014
CH₃, CH₃
H
F
H
F
H

I-1015
CH₃, CH₂CH₃
H
F
H
F
H

I-1016
CH₃, CH(CH₃)₂
H
F
H
F
H

I-1017
CH₃, C₃H₇
H
F
H
F
H

I-1018
CH₃, C(═O)CH₃
H
F
H
F
H

I-1019
CH₃, C(═O)CH₂CH₃
H
F
H
F
H

I-1020
CH₃, C(═O)C₃H₇
H
F
H
F
H

I-1021
CH₃, CH₂CN
H
F
H
F
H

I-1022
CH₃, CH₃
CH₃
F
H
F
H

I-1023
CH₃, CH₂CH₃
CH₃
F
H
F
H

I-1024
CH₃, CH(CH₃)₂
CH₃
F
H
F
H

I-1025
CH₃, C₃H₇
CH₃
F
H
F
H

I-1026
CH₃, C(═O)CH₃
CH₃
F
H
F
H

I-1027
CH₃, C(═O)CH₂CH₃
CH₃
F
H
F
H

I-1028
CH₃, C(═O)C₃H₇
CH₃
F
H
F
H

I-1029
CH₃, CH₂CN
CH₃
F
H
F
H

I-1030
CH₃, CH₃
H
CH₃
CH₃
F
H

I-1031
CH₃, CH₂CH₃
H
CH₃
CH₃
F
H

I-1032
CH₃, CH(CH₃)₂
H
CH₃
CH₃
F
H

I-1033
CH₃, C₃H₇
H
CH₃
CH₃
F
H

I-1034
CH₃, C(═O)CH₃
H
CH₃
CH₃
F
H

I-1035
CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
F
H

I-1036
CH₃, C(═O)C₃H₇
H
CH₃
CH₃
F
H

I-1037
CH₃, CH₂CN
H
CH₃
CH₃
F
H

I-1038
CH₃, CH₃
CH₃
CH₃
CH₃
F
H

I-1039
CH₃, CH₂CH₃
CH₃
CH₃
CH₃
F
H

I-1040
CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
F
H

I-1041
CH₃, C₃H₇
CH₃
CH₃
CH₃
F
H

I-1042
CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
F
H

I-1043
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
H

I-1044
CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
H

I-1045
CH₃, CH₂CN
CH₃
CH₃
CH₃
F
H

I-1046
CH₃, CH₃
H
F
CH₃
F
H

I-1047
CH₃, CH₂CH₃
H
F
CH₃
F
H

I-1048
CH₃, CH(CH₃)₂
H
F
CH₃
F
H

I-1049
CH₃, C₃H₇
H
F
CH₃
F
H

I-1050
CH₃, C(═O)CH₃
H
F
CH₃
F
H

I-1051
CH₃, C(═O)CH₂CH₃
H
F
CH₃
F
H

I-1052
CH₃, C(═O)C₃H₇
H
F
CH₃
F
H

I-1053
CH₃, CH₂CN
H
F
CH₃
F
H

I-1054
CH₃, CH₃
CH₃
F
CH₃
F
H

I-1055
CH₃, CH₂CH₃
CH₃
F
CH₃
F
H

I-1056
CH₃, CH(CH₃)₂
CH₃
F
CH₃
F
H

I-1057
CH₃, C₃H₇
CH₃
F
CH₃
F
H

I-1058
CH₃, C(═O)CH₃
CH₃
F
CH₃
F
H

I-1059
CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
F
H

I-1060
CH₃, C(═O)C₃H₇
CH₃
F
CH₃
F
H

I-1061
CH₃, CH₂CN
CH₃
F
CH₃
F
H

I-1062
CH₃, CH₃
H
F
F
H
H

I-1063
CH₃, CH₂CH₃
H
F
F
H
H

I-1064
CH₃, CH(CH₃)₂
H
F
F
H
H

I-1065
CH₃, C₃H₇
H
F
F
H
H

I-1066
CH₃, C(═O)CH₃
H
F
F
H
H

I-1067
CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-1068
CH₃, C(═O)C₃H₇
H
F
F
H
H

I-1069
CH₃, CH₂CN
H
F
F
H
H

I-1070
CH₃, CH₃
CH₃
F
F
H
H

I-1071
CH₃, CH₂CH₃
CH₃
F
F
H
H

I-1072
CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-1073
CH₃, C₃H₇
CH₃
F
F
H
H

I-1074
CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-1075
CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-1076
CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-1077
CH₃, CH₂CN
CH₃
F
F
H
H

I-1078
CH₃, CH₃
H
C═O
F
H

I-1079
CH₃, CH₂CH₃
H
C═O
F
H

I-1080
CH₃, CH(CH₃)₂
H
C═O
F
H

I-1081
CH₃, C₃H₇
H
C═O
F
H

I-1082
CH₃, C(═O)CH₃
H
C═O
F
H

I-1083
CH₃, C(═O)CH₂CH₃
H
C═O
F
H

I-1084
CH₃, C(═O)C₃H₇
H
C═O
F
H

I-1085
CH₃, CH₂CN
H
C═O
F
H

I-1086
CH₃, CH₃
CH₃
C═O
F
H

I-1087
CH₃, CH₂CH₃
CH₃
C═O
F
H

I-1088
CH₃, CH(CH₃)₂
CH₃
C═O
F
H

I-1089
CH₃, C₃H₇
CH₃
C═O
F
H

I-1090
CH₃, C(═O)CH₃
CH₃
C═O
F
H

I-1091
CH₃, C(═O)CH₂CH₃
CH₃
C═O
F
H

I-1092
CH₃, C(═O)C₃H₇
CH₃
C═O
F
H

I-1093
CH₃, CH₂CN
CH₃
C═O
F
H

I-1094
CH₃, CH₃
H
H
H
CH₃
CH₃

I-1095
CH₃, CH₂CH₃
H
H
H
CH₃
CH₃

I-1096
CH₃, CH(CH₃)₂
H
H
H
CH₃
CH₃

I-1097
CH₃, C₃H₇
H
H
H
CH₃
CH₃

I-1098
CH₃, C(═O)CH₃
H
H
H
CH₃
CH₃

I-1099
CH₃, C(═O)CH₂CH₃
H
H
H
CH₃
CH₃

I-1100
CH₃, C(═O)C₃H₇
H
H
H
CH₃
CH₃

I-1101
CH₃, CH₂CN
H
H
H
CH₃
CH₃

I-1102
CH₃, CH₃
CH₃
H
H
CH₃
CH₃

I-1103
CH₃, CH₂CH₃
CH₃
H
H
CH₃
CH₃

I-1104
CH₃, CH(CH₃)₂
CH₃
H
H
CH₃
CH₃

I-1105
CH₃, C₃H₇
CH₃
H
H
CH₃
CH₃

I-1106
CH₃, C(═O)CH₃
CH₃
H
H
CH₃
CH₃

I-1107
CH₃, C(═O)CH₂CH₃
CH₃
H
H
CH₃
CH₃

I-1108
CH₃, C(═O)C₃H₇
CH₃
H
H
CH₃
CH₃

I-1109
CH₃, CH₂CN
CH₃
H
H
CH₃
CH₃

I-1110
CH₃, CH₃
H
CH₃
H
CH₃
CH₃

I-1111
CH₃, CH₂CH₃
H
CH₃
H
CH₃
CH₃

I-1112
CH₃, CH(CH₃)₂
H
CH₃
H
CH₃
CH₃

I-1113
CH₃, C₃H₇
H
CH₃
H
CH₃
CH₃

I-1114
CH₃, C(═O)CH₃
H
CH₃
H
CH₃
CH₃

I-1115
CH₃, C(═O)CH₂CH₃
H
CH₃
H
CH₃
CH₃

I-1116
CH₃, C(═O)C₃H₇
H
CH₃
H
CH₃
CH₃

I-1117
CH₃, CH₂CN
H
CH₃
H
CH₃
CH₃

I-1118
CH₃, CH₃
CH₃
CH₃
H
CH₃
CH₃

I-1119
CH₃, CH₂CH₃
CH₃
CH₃
H
CH₃
CH₃

I-1120
CH₃, CH(CH₃)₂
CH₃
CH₃
H
CH₃
CH₃

I-1121
CH₃, C₃H₇
CH₃
CH₃
H
CH₃
CH₃

I-1122
CH₃, C(═O)CH₃
CH₃
CH₃
H
CH₃
CH₃

I-1123
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
CH₃
CH₃

I-1124
CH₃, C(═O)C₃H₇
CH₃
CH₃
H
CH₃
CH₃

I-1125
CH₃, CH₂CN
CH₃
CH₃
H
CH₃
CH₃

I-1126
CH₃, CH₃
H
F
H
CH₃
CH₃

I-1127
CH₃, CH₂CH₃
H
F
H
CH₃
CH₃

I-1128
CH₃, CH(CH₃)₂
H
F
H
CH₃
CH₃

I-1129
CH₃, C₃H₇
H
F
H
CH₃
CH₃

I-1130
CH₃, C(═O)CH₃
H
F
H
CH₃
CH₃

I-1131
CH₃, C(═O)CH₂CH₃
H
F
H
CH₃
CH₃

I-1132
CH₃, C(═O)C₃H₇
H
F
H
CH₃
CH₃

I-1133
CH₃, CH₂CN
H
F
H
CH₃
CH₃

I-1134
CH₃, CH₃
CH₃
F
H
CH₃
CH₃

I-1135
CH₃, CH₂CH₃
CH₃
F
H
CH₃
CH₃

I-1136
CH₃, CH(CH₃)₂
CH₃
F
H
CH₃
CH₃

I-1137
CH₃, C₃H₇
CH₃
F
H
CH₃
CH₃

I-1138
CH₃, C(═O)CH₃
CH₃
F
H
CH₃
CH₃

I-1139
CH₃, C(═O)CH₂CH₃
CH₃
F
H
CH₃
CH₃

I-1140
CH₃, C(═O)C₃H₇
CH₃
F
H
CH₃
CH₃

I-1141
CH₃, CH₂CN
CH₃
F
H
CH₃
CH₃

I-1142
CH₃, CH₃
H
CH₃
CH₃
CH₃
CH₃

I-1143
CH₃, CH₂CH₃
H
CH₃
CH₃
CH₃
CH₃

I-1144
CH₃, CH(CH₃)₂
H
CH₃
CH₃
CH₃
CH₃

I-1145
CH₃, C₃H₇
H
CH₃
CH₃
CH₃
CH₃

I-1146
CH₃, C(═O)CH₃
H
CH₃
CH₃
CH₃
CH₃

I-1147
CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
CH₃
CH₃

I-1148
CH₃, C(═O)C₃H₇
H
CH₃
CH₃
CH₃
CH₃

I-1149
CH₃, CH₂CN
H
CH₃
CH₃
CH₃
CH₃

I-1150
CH₃, CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-1151
CH₃, CH₂CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-1152
CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
CH₃
CH₃

I-1153
CH₃, C₃H₇
CH₃
CH₃
CH₃
CH₃
CH₃

I-1154
CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-1155
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-1156
CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
CH₃
CH₃

I-1157
CH₃, CH₂CN
CH₃
CH₃
CH₃
CH₃
CH₃

I-1158
CH₃, CH₃
H
F
CH₃
CH₃
CH₃

I-1159
CH₃, CH₂CH₃
H
F
CH₃
CH₃
CH₃

I-1160
CH₃, CH(CH₃)₂
H
F
CH₃
CH₃
CH₃

I-1161
CH₃, C₃H₇
H
F
CH₃
CH₃
CH₃

I-1162
CH₃, C(═O)CH₃
H
F
CH₃
CH₃
CH₃

I-1163
CH₃, C(═O)CH₂CH₃
H
F
CH₃
CH₃
CH₃

I-1164
CH₃, C(═O)C₃H₇
H
F
CH₃
CH₃
CH₃

I-1165
CH₃, CH₂CN
H
F
CH₃
CH₃
CH₃

I-1166
CH₃, CH₃
CH₃
F
CH₃
CH₃
CH₃

I-1167
CH₃, CH₂CH₃
CH₃
F
CH₃
CH₃
CH₃

I-1168
CH₃, CH(CH₃)₂
CH₃
F
CH₃
CH₃
CH₃

I-1169
CH₃, C₃H₇
CH₃
F
CH₃
CH₃
CH₃

I-1170
CH₃, C(═O)CH₃
CH₃
F
CH₃
CH₃
CH₃

I-1171
CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
CH₃
CH₃

I-1172
CH₃, C(═O)C₃H₇
CH₃
F
CH₃
CH₃
CH₃

I-1173
CH₃, CH₂CN
CH₃
F
CH₃
CH₃
CH₃

I-1174
CH₃, CH₃
H
F
F
H
H

I-1175
CH₃, CH₂CH₃
H
F
F
H
H

I-1176
CH₃, CH(CH₃)₂
H
F
F
H
H

I-1177
CH₃, C₃H₇
H
F
F
H
H

I-1178
CH₃, C(═O)CH₃
H
F
F
H
H

I-1179
CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-1180
CH₃, C(═O)C₃H₇
H
F
F
H
H

I-1181
CH₃, CH₂CN
H
F
F
H
H

I-1182
CH₃, CH₃
CH₃
F
F
H
H

I-1183
CH₃, CH₂CH₃
CH₃
F
F
H
H

I-1184
CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-1185
CH₃, C₃H₇
CH₃
F
F
H
H

I-1186
CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-1187
CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-1188
CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-1189
CH₃, CH₂CN
CH₃
F
F
H
H

I-1190
CH₃, CH₃
H
C═O
CH₃
CH₃

I-1191
CH₃, CH₂CH₃
H
C═O
CH₃
CH₃

I-1192
CH₃, CH(CH₃)₂
H
C═O
CH₃
CH₃

I-1193
CH₃, C₃H₇
H
C═O
CH₃
CH₃

I-1194
CH₃, C(═O)CH₃
H
C═O
CH₃
CH₃

I-1195
CH₃, C(═O)CH₂CH₃
H
C═O
CH₃
CH₃

I-1196
CH₃, C(═O)C₃H₇
H
C═O
CH₃
CH₃

I-1197
CH₃, CH₂CN
H
C═O
CH₃
CH₃

I-1198
CH₃, CH₃
CH₃
C═O
CH₃
CH₃

I-1199
CH₃, CH₂CH₃
CH₃
C═O
CH₃
CH₃

I-1200
CH₃, CH(CH₃)₂
CH₃
C═O
CH₃
CH₃

I-1201
CH₃, C₃H₇
CH₃
C═O
CH₃
CH₃

I-1202
CH₃, C(═O)CH₃
CH₃
C═O
CH₃
CH₃

I-1203
CH₃, C(═O)CH₂CH₃
CH₃
C═O
CH₃
CH₃

I-1204
CH₃, C(═O)C₃H₇
CH₃
C═O
CH₃
CH₃

I-1205
CH₃, CH₂CN
CH₃
C═O
CH₃
CH₃

I-1206
CH₃, CH₃
H
H
H
F
CH₃

I-1207
CH₃, CH₂CH₃
H
H
H
F
CH₃

I-1208
CH₃, CH(CH₃)₂
H
H
H
F
CH₃

I-1209
CH₃, C₃H₇
H
H
H
F
CH₃

I-1210
CH₃, C(═O)CH₃
H
H
H
F
CH₃

I-1211
CH₃, C(═O)CH₂CH₃
H
H
H
F
CH₃

I-1212
CH₃, C(═O)C₃H₇
H
H
H
F
CH₃

I-1213
CH₃, CH₂CN
H
H
H
F
CH₃

I-1214
CH₃, CH₃
CH₃
H
H
F
CH₃

I-1215
CH₃, CH₂CH₃
CH₃
H
H
F
CH₃

I-1216
CH₃, CH(CH₃)₂
CH₃
H
H
F
CH₃

I-1217
CH₃, C₃H₇
CH₃
H
H
F
CH₃

I-1218
CH₃, C(═O)CH₃
CH₃
H
H
F
CH₃

I-1219
CH₃, C(═O)CH₂CH₃
CH₃
H
H
F
CH₃

I-1220
CH₃, C(═O)C₃H₇
CH₃
H
H
F
CH₃

I-1221
CH₃, CH₂CN
CH₃
H
H
F
CH₃

I-1222
CH₃, CH₃
H
CH₃
H
F
CH₃

I-1223
CH₃, CH₂CH₃
H
CH₃
H
F
CH₃

I-1224
CH₃, CH(CH₃)₂
H
CH₃
H
F
CH₃

I-1225
CH₃, C₃H₇
H
CH₃
H
F
CH₃

I-1226
CH₃, C(═O)CH₃
H
CH₃
H
F
CH₃

I-1227
CH₃, C(═O)CH₂CH₃
H
CH₃
H
F
CH₃

I-1228
CH₃, C(═O)C₃H₇
H
CH₃
H
F
CH₃

I-1229
CH₃, CH₂CN
H
CH₃
H
F
CH₃

I-1230
CH₃, CH₃
CH₃
CH₃
H
F
CH₃

I-1231
CH₃, CH₂CH₃
CH₃
CH₃
H
F
CH₃

I-1232
CH₃, CH(CH₃)₂
CH₃
CH₃
H
F
CH₃

I-1233
CH₃, C₃H₇
CH₃
CH₃
H
F
CH₃

I-1234
CH₃, C(═O)CH₃
CH₃
CH₃
H
F
CH₃

I-1235
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
F
CH₃

I-1236
CH₃, C(═O)C₃H₇
CH₃
CH₃
H
F
CH₃

I-1237
CH₃, CH₂CN
CH₃
CH₃
H
F
CH₃

I-1238
CH₃, CH₃
H
F
H
F
CH₃

I-1239
CH₃, CH₂CH₃
H
F
H
F
CH₃

I-1240
CH₃, CH(CH₃)₂
H
F
H
F
CH₃

I-1241
CH₃, C₃H₇
H
F
H
F
CH₃

I-1242
CH₃, C(═O)CH₃
H
F
H
F
CH₃

I-1243
CH₃, C(═O)CH₂CH₃
H
F
H
F
CH₃

I-1244
CH₃, C(═O)C₃H₇
H
F
H
F
CH₃

I-1245
CH₃, CH₂CN
H
F
H
F
CH₃

I-1246
CH₃, CH₃
CH₃
F
H
F
CH₃

I-1247
CH₃, CH₂CH₃
CH₃
F
H
F
CH₃

I-1248
CH₃, CH(CH₃)₂
CH₃
F
H
F
CH₃

I-1249
CH₃, C₃H₇
CH₃
F
H
F
CH₃

I-1250
CH₃, C(═O)CH₃
CH₃
F
H
F
CH₃

I-1251
CH₃, C(═O)CH₂CH₃
CH₃
F
H
F
CH₃

I-1252
CH₃, C(═O)C₃H₇
CH₃
F
H
F
CH₃

I-1253
CH₃, CH₂CN
CH₃
F
H
F
CH₃

I-1254
CH₃, CH₃
H
CH₃
CH₃
F
CH₃

I-1255
CH₃, CH₂CH₃
H
CH₃
CH₃
F
CH₃

I-1256
CH₃, CH(CH₃)₂
H
CH₃
CH₃
F
CH₃

I-1257
CH₃, C₃H₇
H
CH₃
CH₃
F
CH₃

I-1258
CH₃, C(═O)CH₃
H
CH₃
CH₃
F
CH₃

I-1259
CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
F
CH₃

I-1260
CH₃, C(═O)C₃H₇
H
CH₃
CH₃
F
CH₃

I-1261
CH₃, CH₂CN
H
CH₃
CH₃
F
CH₃

I-1262
CH₃, CH₃
CH₃
CH₃
CH₃
F
CH₃

I-1263
CH₃, CH₂CH₃
CH₃
CH₃
CH₃
F
CH₃

I-1264
CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
F
CH₃

I-1265
CH₃, C₃H₇
CH₃
CH₃
CH₃
F
CH₃

I-1266
CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
F
CH₃

I-1267
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
CH₃

I-1268
CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
CH₃

I-1269
CH₃, CH₂CN
CH₃
CH₃
CH₃
F
CH₃

I-1270
CH₃, CH₃
H
F
CH₃
F
CH₃

I-1271
CH₃, CH₂CH₃
H
F
CH₃
F
CH₃

I-1272
CH₃, CH(CH₃)₂
H
F
CH₃
F
CH₃

I-1273
CH₃, C₃H₇
H
F
CH₃
F
CH₃

I-1274
CH₃, C(═O)CH₃
H
F
CH₃
F
CH₃

I-1275
CH₃, C(═O)CH₂CH₃
H
F
CH₃
F
CH₃

I-1276
CH₃, C(═O)C₃H₇
H
F
CH₃
F
CH₃

I-1277
CH₃, CH₂CN
H
F
CH₃
F
CH₃

I-1278
CH₃, CH₃
CH₃
F
CH₃
F
CH₃

I-1279
CH₃, CH₂CH₃
CH₃
F
CH₃
F
CH₃

I-1280
CH₃, CH(CH₃)₂
CH₃
F
CH₃
F
CH₃

I-1281
CH₃, C₃H₇
CH₃
F
CH₃
F
CH₃

I-1282
CH₃, C(═O)CH₃
CH₃
F
CH₃
F
CH₃

I-1283
CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
F
CH₃

I-1284
CH₃, C(═O)C₃H₇
CH₃
F
CH₃
F
CH₃

I-1285
CH₃, CH₂CN
CH₃
F
CH₃
F
CH₃

I-1286
CH₃, CH₃
H
F
F
H
H

I-1287
CH₃, CH₂CH₃
H
F
F
H
H

I-1288
CH₃, CH(CH₃)₂
H
F
F
H
H

I-1289
CH₃, C₃H₇
H
F
F
H
H

I-1290
CH₃, C(═O)CH₃
H
F
F
H
H

I-1291
CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-1292
CH₃, C(═O)C₃H₇
H
F
F
H
H

I-1293
CH₃, CH₂CN
H
F
F
H
H

I-1294
CH₃, CH₃
CH₃
F
F
H
H

I-1295
CH₃, CH₂CH₃
CH₃
F
F
H
H

I-1296
CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-1297
CH₃, C₃H₇
CH₃
F
F
H
H

I-1298
CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-1299
CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-1300
CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-1301
CH₃, CH₂CN
CH₃
F
F
H
H

I-1302
CH₃, CH₃
H
C═O
F
CH₃

I-1303
CH₃, CH₂CH₃
H
C═O
F
CH₃

I-1304
CH₃, CH(CH₃)₂
H
C═O
F
CH₃

I-1305
CH₃, C₃H₇
H
C═O
F
CH₃

I-1306
CH₃, C(═O)CH₃
H
C═O
F
CH₃

I-1307
CH₃, C(═O)CH₂CH₃
H
C═O
F
CH₃

I-1308
CH₃, C(═O)C₃H₇
H
C═O
F
CH₃

I-1309
CH₃, CH₂CN
H
C═O
F
CH₃

I-1310
CH₃, CH₃
CH₃
C═O
F
CH₃

I-1311
CH₃, CH₂CH₃
CH₃
C═O
F
CH₃

I-1312
CH₃, CH(CH₃)₂
CH₃
C═O
F
CH₃

I-1313
CH₃, C₃H₇
CH₃
C═O
F
CH₃

I-1314
CH₃, C(═O)CH₃
CH₃
C═O
F
CH₃

I-1315
CH₃, C(═O)CH₂CH₃
CH₃
C═O
F
CH₃

I-1316
CH₃, C(═O)C₃H₇
CH₃
C═O
F
CH₃

I-1317
CH₃, CH₂CN
CH₃
C═O
F
CH₃

I-1318
CH₃, CH₃
H
H
H
F
F

I-1319
CH₃, CH₂CH₃
H
H
H
F
F

I-1320
CH₃, CH(CH₃)₂
H
H
H
F
F

I-1321
CH₃, C₃H₇
H
H
H
F
F

I-1322
CH₃, C(═O)CH₃
H
H
H
F
F

I-1323
CH₃, C(═O)CH₂CH₃
H
H
H
F
F

I-1324
CH₃, C(═O)C₃H₇
H
H
H
F
F

I-1325
CH₃, CH₂CN
H
H
H
F
F

I-1326
CH₃, CH₃
CH₃
H
H
F
F

I-1327
CH₃, CH₂CH₃
CH₃
H
H
F
F

I-1328
CH₃, CH(CH₃)₂
CH₃
H
H
F
F

I-1329
CH₃, C₃H₇
CH₃
H
H
F
F

I-1330
CH₃, C(═O)CH₃
CH₃
H
H
F
F

I-1331
CH₃, C(═O)CH₂CH₃
CH₃
H
H
F
F

I-1332
CH₃, C(═O)C₃H₇
CH₃
H
H
F
F

I-1333
CH₃, CH₂CN
CH₃
H
H
F
F

I-1334
CH₃, CH₃
H
CH₃
H
F
F

I-1335
CH₃, CH₂CH₃
H
CH₃
H
F
F

I-1336
CH₃, CH(CH₃)₂
H
CH₃
H
F
F

I-1337
CH₃, C₃H₇
H
CH₃
H
F
F

I-1338
CH₃, C(═O)CH₃
H
CH₃
H
F
F

I-1339
CH₃, C(═O)CH₂CH₃
H
CH₃
H
F
F

I-1340
CH₃, C(═O)C₃H₇
H
CH₃
H
F
F

I-1341
CH₃, CH₂CN
H
CH₃
H
F
F

I-1342
CH₃, CH₃
CH₃
CH₃
H
F
F

I-1343
CH₃, CH₂CH₃
CH₃
CH₃
H
F
F

I-1344
CH₃, CH(CH₃)₂
CH₃
CH₃
H
F
F

I-1345
CH₃, C₃H₇
CH₃
CH₃
H
F
F

I-1346
CH₃, C(═O)CH₃
CH₃
CH₃
H
F
F

I-1347
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
F
F

I-1348
CH₃, C(═O)C₃H₇
CH₃
CH₃
H
F
F

I-1349
CH₃, CH₂CN
CH₃
CH₃
H
F
F

I-1350
CH₃, CH₃
H
F
H
F
F

I-1351
CH₃, CH₂CH₃
H
F
H
F
F

I-1352
CH₃, CH(CH₃)₂
H
F
H
F
F

I-1353
CH₃, C₃H₇
H
F
H
F
F

I-1354
CH₃, C(═O)CH₃
H
F
H
F
F

I-1355
CH₃, C(═O)CH₂CH₃
H
F
H
F
F

I-1356
CH₃, C(═O)C₃H₇
H
F
H
F
F

I-1357
CH₃, CH₂CN
H
F
H
F
F

I-1358
CH₃, CH₃
CH₃
F
H
F
F

I-1359
CH₃, CH₂CH₃
CH₃
F
H
F
F

I-1360
CH₃, CH(CH₃)₂
CH₃
F
H
F
F

I-1361
CH₃, C₃H₇
CH₃
F
H
F
F

I-1362
CH₃, C(═O)CH₃
CH₃
F
H
F
F

I-1363
CH₃, C(═O)CH₂CH₃
CH₃
F
H
F
F

I-1364
CH₃, C(═O)C₃H₇
CH₃
F
H
F
F

I-1365
CH₃, CH₂CN
CH₃
F
H
F
F

I-1366
CH₃, CH₃
H
CH₃
CH₃
F
F

I-1367
CH₃, CH₂CH₃
H
CH₃
CH₃
F
F

I-1368
CH₃, CH(CH₃)₂
H
CH₃
CH₃
F
F

I-1369
CH₃, C₃H₇
H
CH₃
CH₃
F
F

I-1370
CH₃, C(═O)CH₃
H
CH₃
CH₃
F
F

I-1371
CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
F
F

I-1372
CH₃, C(═O)C₃H₇
H
CH₃
CH₃
F
F

I-1373
CH₃, CH₂CN
H
CH₃
CH₃
F
F

I-1374
CH₃, CH₃
CH₃
CH₃
CH₃
F
F

I-1375
CH₃, CH₂CH₃
CH₃
CH₃
CH₃
F
F

I-1376
CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
F
F

I-1377
CH₃, C₃H₇
CH₃
CH₃
CH₃
F
F

I-1378
CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
F
F

I-1379
CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
F

I-1380
CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
F

I-1381
CH₃, CH₂CN
CH₃
CH₃
CH₃
F
F

I-1382
CH₃, CH₃
H
F
CH₃
F
F

I-1383
CH₃, CH₂CH₃
H
F
CH₃
F
F

I-1384
CH₃, CH(CH₃)₂
H
F
CH₃
F
F

I-1385
CH₃, C₃H₇
H
F
CH₃
F
F

I-1386
CH₃, C(═O)CH₃
H
F
CH₃
F
F

I-1387
CH₃, C(═O)CH₂CH₃
H
F
CH₃
F
F

I-1388
CH₃, C(═O)C₃H₇
H
F
CH₃
F
F

I-1389
CH₃, CH₂CN
H
F
CH₃
F
F

I-1390
CH₃, CH₃
CH₃
F
CH₃
F
F

I-1391
CH₃, CH₂CH₃
CH₃
F
CH₃
F
F

I-1392
CH₃, CH(CH₃)₂
CH₃
F
CH₃
F
F

I-1393
CH₃, C₃H₇
CH₃
F
CH₃
F
F

I-1394
CH₃, C(═O)CH₃
CH₃
F
CH₃
F
F

I-1395
CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
F
F

I-1396
CH₃, C(═O)C₃H₇
CH₃
F
CH₃
F
F

I-1397
CH₃, CH₂CN
CH₃
F
CH₃
F
F

I-1398
CH₃, CH₃
H
F
F
H
H

I-1399
CH₃, CH₂CH₃
H
F
F
H
H

I-1400
CH₃, CH(CH₃)₂
H
F
F
H
H

I-1401
CH₃, C₃H₇
H
F
F
H
H

I-1402
CH₃, C(═O)CH₃
H
F
F
H
H

I-1403
CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-1404
CH₃, C(═O)C₃H₇
H
F
F
H
H

I-1405
CH₃, CH₂CN
H
F
F
H
H

I-1406
CH₃, CH₃
CH₃
F
F
H
H

I-1407
CH₃, CH₂CH₃
CH₃
F
F
H
H

I-1408
CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-1409
CH₃, C₃H₇
CH₃
F
F
H
H

I-1410
CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-1411
CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-1412
CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-1413
CH₃, CH₂CN
CH₃
F
F
H
H

I-1414
CH₃, CH₃
H
C═O
F
F

I-1415
CH₃, CH₂CH₃
H
C═O
F
F

I-1416
CH₃, CH(CH₃)₂
H
C═O
F
F

I-1417
CH₃, C₃H₇
H
C═O
F
F

I-1418
CH₃, C(═O)CH₃
H
C═O
F
F

I-1419
CH₃, C(═O)CH₂CH₃
H
C═O
F
F

I-1420
CH₃, C(═O)C₃H₇
H
C═O
F
F

I-1421
CH₃, CH₂CN
H
C═O
F
F

I-1422
CH₃, CH₃
CH₃
C═O
F
F

I-1423
CH₃, CH₂CH₃
CH₃
C═O
F
F

I-1424
CH₃, CH(CH₃)₂
CH₃
C═O
F
F

I-1425
CH₃, C₃H₇
CH₃
C═O
F
F

I-1426
CH₃, C(═O)CH₃
CH₃
C═O
F
F

I-1427
CH₃, C(═O)CH₂CH₃
CH₃
C═O
F
F

I-1428
CH₃, C(═O)C₃H₇
CH₃
C═O
F
F

I-1429
CH₃, CH₂CN
CH₃
C═O
F
F

I-1430
CH₂CH₃, CH₃
H
H
H
H
H

I-1431
CH₂CH₃, CH₂CH₃
H
H
H
H
H

I-1432
CH₂CH₃, CH(CH₃)₂
H
H
H
H
H

I-1433
CH₂CH₃, C₃H₇
H
H
H
H
H

I-1434
CH₂CH₃, C(═O)CH₃
H
H
H
H
H

I-1435
CH₂CH₃, C(═O)CH₂CH₃
H
H
H
H
H

I-1436
CH₂CH₃, C(═O)C₃H₇
H
H
H
H
H

I-1437
CH₂CH₃, CH₂CN
H
H
H
H
H

I-1438
CH₂CH₃, CH₃
CH₃
H
H
H
H

I-1439
CH₂CH₃, CH₂CH₃
CH₃
H
H
H
H

I-1440
CH₂CH₃, CH(CH₃)₂
CH₃
H
H
H
H

I-1441
CH₂CH₃, C₃H₇
CH₃
H
H
H
H

I-1442
CH₂CH₃, C(═O)CH₃
CH₃
H
H
H
H

I-1443
CH₂CH₃, C(═O)CH₂CH₃
CH₃
H
H
H
H

I-1444
CH₂CH₃, C(═O)C₃H₇
CH₃
H
H
H
H

I-1445
CH₂CH₃, CH₂CN
CH₃
H
H
H
H

I-1446
CH₂CH₃, CH₃
H
CH₃
H
H
H

I-1447
CH₂CH₃, CH₂CH₃
H
CH₃
H
H
H

I-1448
CH₂CH₃, CH(CH₃)₂
H
CH₃
H
H
H

I-1449
CH₂CH₃, C₃H₇
H
CH₃
H
H
H

I-1450
CH₂CH₃, C(═O)CH₃
H
CH₃
H
H
H

I-1451
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
H
H
H

I-1452
CH₂CH₃, C(═O)C₃H₇
H
CH₃
H
H
H

I-1453
CH₂CH₃, CH₂CN
H
CH₃
H
H
H

I-1454
CH₂CH₃, CH₃
CH₃
CH₃
H
H
H

I-1455
CH₂CH₃, CH₂CH₃
CH₃
CH₃
H
H
H

I-1456
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
H
H
H

I-1457
CH₂CH₃, C₃H₇
CH₃
CH₃
H
H
H

I-1458
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
H
H
H

I-1459
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
H
H

I-1460
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
H
H
H

I-1461
CH₂CH₃, CH₂CN
CH₃
CH₃
H
H
H

I-1462
CH₂CH₃, CH₃
H
F
H
H
H

I-1463
CH₂CH₃, CH₂CH₃
H
F
H
H
H

I-1464
CH₂CH₃, CH(CH₃)₂
H
F
H
H
H

I-1465
CH₂CH₃, C₃H₇
H
F
H
H
H

I-1466
CH₂CH₃, C(═O)CH₃
H
F
H
H
H

I-1467
CH₂CH₃, C(═O)CH₂CH₃
H
F
H
H
H

I-1468
CH₂CH₃, C(═O)C₃H₇
H
F
H
H
H

I-1469
CH₂CH₃, CH₂CN
H
F
H
H
H

I-1470
CH₂CH₃, CH₃
CH₃
F
H
H
H

I-1471
CH₂CH₃, CH₂CH₃
CH₃
F
H
H
H

I-1472
CH₂CH₃, CH(CH₃)₂
CH₃
F
H
H
H

I-1473
CH₂CH₃, C₃H₇
CH₃
F
H
H
H

I-1474
CH₂CH₃, C(═O)CH₃
CH₃
F
H
H
H

I-1475
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
H
H
H

I-1476
CH₂CH₃, C(═O)C₃H₇
CH₃
F
H
H
H

I-1477
CH₂CH₃, CH₂CN
CH₃
F
H
H
H

I-1478
CH₂CH₃, CH₃
H
CH₃
CH₃
H
H

I-1479
CH₂CH₃, CH₂CH₃
H
CH₃
CH₃
H
H

I-1480
CH₂CH₃, CH(CH₃)₂
H
CH₃
CH₃
H
H

I-1481
CH₂CH₃, C₃H₇
H
CH₃
CH₃
H
H

I-1482
CH₂CH₃, C(═O)CH₃
H
CH₃
CH₃
H
H

I-1483
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
H
H

I-1484
CH₂CH₃, C(═O)C₃H₇
H
CH₃
CH₃
H
H

I-1485
CH₂CH₃, CH₂CN
H
CH₃
CH₃
H
H

I-1486
CH₂CH₃, CH₃
CH₃
CH₃
CH₃
H
H

I-1487
CH₂CH₃, CH₂CH₃
CH₃
CH₃
CH₃
H
H

I-1488
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
H
H

I-1489
CH₂CH₃, C₃H₇
CH₃
CH₃
CH₃
H
H

I-1490
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
H
H

I-1491
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
H
H

I-1492
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
H
H

I-1493
CH₂CH₃, CH₂CN
CH₃
CH₃
CH₃
H
H

I-1494
CH₂CH₃, CH₃
H
F
CH₃
H
H

I-1495
CH₂CH₃, CH₂CH₃
H
F
CH₃
H
H

I-1496
CH₂CH₃, CH(CH₃)₂
H
F
CH₃
H
H

I-1497
CH₂CH₃, C₃H₇
H
F
CH₃
H
H

I-1498
CH₂CH₃, C(═O)CH₃
H
F
CH₃
H
H

I-1499
CH₂CH₃, C(═O)CH₂CH₃
H
F
CH₃
H
H

I-1500
CH₂CH₃, C(═O)C₃H₇
H
F
CH₃
H
H

I-1501
CH₂CH₃, CH₂CN
H
F
CH₃
H
H

I-1502
CH₂CH₃, CH₃
CH₃
F
CH₃
H
H

I-1503
CH₂CH₃, CH₂CH₃
CH₃
F
CH₃
H
H

I-1504
CH₂CH₃, CH(CH₃)₂
CH₃
F
CH₃
H
H

I-1505
CH₂CH₃, C₃H₇
CH₃
F
CH₃
H
H

I-1506
CH₂CH₃, C(═O)CH₃
CH₃
F
CH₃
H
H

I-1507
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
H
H

I-1508
CH₂CH₃, C(═O)C₃H₇
CH₃
F
CH₃
H
H

I-1509
CH₂CH₃, CH₂CN
CH₃
F
CH₃
H
H

I-1510
CH₂CH₃, CH₃
H
F
F
H
H

I-1511
CH₂CH₃, CH₂CH₃
H
F
F
H
H

I-1512
CH₂CH₃, CH(CH₃)₂
H
F
F
H
H

I-1513
CH₂CH₃, C₃H₇
H
F
F
H
H

I-1514
CH₂CH₃, C(═O)CH₃
H
F
F
H
H

I-1515
CH₂CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-1516
CH₂CH₃, C(═O)C₃H₇
H
F
F
H
H

I-1517
CH₂CH₃, CH₂CN
H
F
F
H
H

I-1518
CH₂CH₃, CH₃
CH₃
F
F
H
H

I-1519
CH₂CH₃, CH₂CH₃
CH₃
F
F
H
H

I-1520
CH₂CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-1521
CH₂CH₃, C₃H₇
CH₃
F
F
H
H

I-1522
CH₂CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-1523
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-1524
CH₂CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-1525
CH₂CH₃, CH₂CN
CH₃
F
F
H
H

I-1526
CH₂CH₃, CH₃
H
C═O
H
H

I-1527
CH₂CH₃, CH₂CH₃
H
C═O
H
H

I-1528
CH₂CH₃, CH(CH₃)₂
H
C═O
H
H

I-1529
CH₂CH₃, C₃H₇
H
C═O
H
H

I-1530
CH₂CH₃, C(═O)CH₃
H
C═O
H
H

I-1531
CH₂CH₃, C(═O)CH₂CH₃
H
C═O
H
H

I-1532
CH₂CH₃, C(═O)C₃H₇
H
C═O
H
H

I-1533
CH₂CH₃, CH₂CN
H
C═O
H
H

I-1534
CH₂CH₃, CH₃
CH₃
C═O
H
H

I-1535
CH₂CH₃, CH₂CH₃
CH₃
C═O
H
H

I-1536
CH₂CH₃, CH(CH₃)₂
CH₃
C═O
H
H

I-1537
CH₂CH₃, C₃H₇
CH₃
C═O
H
H

I-1538
CH₂CH₃, C(═O)CH₃
CH₃
C═O
H
H

I-1539
CH₂CH₃, C(═O)CH₂CH₃
CH₃
C═O
H
H

I-1540
CH₂CH₃, C(═O)C₃H₇
CH₃
C═O
H
H

I-1541
CH₂CH₃, CH₂CN
CH₃
C═O
H
H

I-1542
CH₂CH₃, CH₃
H
H
H
CH₃
H

I-1543
CH₂CH₃, CH₂CH₃
H
H
H
CH₃
H

I-1544
CH₂CH₃, CH(CH₃)₂
H
H
H
CH₃
H

I-1545
CH₂CH₃, C₃H₇
H
H
H
CH₃
H

I-1546
CH₂CH₃, C(═O)CH₃
H
H
H
CH₃
H

I-1547
CH₂CH₃, C(═O)CH₂CH₃
H
H
H
CH₃
H

I-1548
CH₂CH₃, C(═O)C₃H₇
H
H
H
CH₃
H

I-1549
CH₂CH₃, CH₂CN
H
H
H
CH₃
H

I-1550
CH₂CH₃, CH₃
CH₃
H
H
CH₃
H

I-1551
CH₂CH₃, CH₂CH₃
CH₃
H
H
CH₃
H

I-1552
CH₂CH₃, CH(CH₃)₂
CH₃
H
H
CH₃
H

I-1553
CH₂CH₃, C₃H₇
CH₃
H
H
CH₃
H

I-1554
CH₂CH₃, C(═O)CH₃
CH₃
H
H
CH₃
H

I-1555
CH₂CH₃, C(═O)CH₂CH₃
CH₃
H
H
CH₃
H

I-1556
CH₂CH₃, C(═O)C₃H₇
CH₃
H
H
CH₃
H

I-1557
CH₂CH₃, CH₂CN
CH₃
H
H
CH₃
H

I-1558
CH₂CH₃, CH₃
H
CH₃
H
CH₃
H

I-1559
CH₂CH₃, CH₂CH₃
H
CH₃
H
CH₃
H

I-1560
CH₂CH₃, CH(CH₃)₂
H
CH₃
H
CH₃
H

I-1561
CH₂CH₃, C₃H₇
H
CH₃
H
CH₃
H

I-1562
CH₂CH₃, C(═O)CH₃
H
CH₃
H
CH₃
H

I-1563
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
H
CH₃
H

I-1564
CH₂CH₃, C(═O)C₃H₇
H
CH₃
H
CH₃
H

I-1565
CH₂CH₃, CH₂CN
H
CH₃
H
CH₃
H

I-1566
CH₂CH₃, CH₃
CH₃
CH₃
H
CH₃
H

I-1567
CH₂CH₃, CH₂CH₃
CH₃
CH₃
H
CH₃
H

I-1568
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
H
CH₃
H

I-1569
CH₂CH₃, C₃H₇
CH₃
CH₃
H
CH₃
H

I-1570
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
H
CH₃
H

I-1571
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
CH₃
H

I-1572
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
H
CH₃
H

I-1573
CH₂CH₃, CH₂CN
CH₃
CH₃
H
CH₃
H

I-1574
CH₂CH₃, CH₃
H
F
H
CH₃
H

I-1575
CH₂CH₃, CH₂CH₃
H
F
H
CH₃
H

I-1576
CH₂CH₃, CH(CH₃)₂
H
F
H
CH₃
H

I-1577
CH₂CH₃, C₃H₇
H
F
H
CH₃
H

I-1578
CH₂CH₃, C(═O)CH₃
H
F
H
CH₃
H

I-1579
CH₂CH₃, C(═O)CH₂CH₃
H
F
H
CH₃
H

I-1580
CH₂CH₃, C(═O)C₃H₇
H
F
H
CH₃
H

I-1581
CH₂CH₃, CH₂CN
H
F
H
CH₃
H

I-1582
CH₂CH₃, CH₃
CH₃
F
H
CH₃
H

I-1583
CH₂CH₃, CH₂CH₃
CH₃
F
H
CH₃
H

I-1584
CH₂CH₃, CH(CH₃)₂
CH₃
F
H
CH₃
H

I-1585
CH₂CH₃, C₃H₇
CH₃
F
H
CH₃
H

I-1586
CH₂CH₃, C(═O)CH₃
CH₃
F
H
CH₃
H

I-1587
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
H
CH₃
H

I-1588
CH₂CH₃, C(═O)C₃H₇
CH₃
F
H
CH₃
H

I-1589
CH₂CH₃, CH₂CN
CH₃
F
H
CH₃
H

I-1590
CH₂CH₃, H
H
CH₃
CH₃
CH₃
H

I-1591
CH₂CH₃, CH₃
H
CH₃
CH₃
CH₃
H

I-1592
CH₂CH₃, CH₂CH₃
H
CH₃
CH₃
CH₃
H

I-1593
CH₂CH₃, CH(CH₃)₂
H
CH₃
CH₃
CH₃
H

I-1594
CH₂CH₃, C₃H₇
H
CH₃
CH₃
CH₃
H

I-1595
CH₂CH₃, C(═O)CH₃
H
CH₃
CH₃
CH₃
H

I-1596
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
CH₃
H

I-1597
CH₂CH₃, C(═O)C₃H₇
H
CH₃
CH₃
CH₃
H

I-1598
CH₂CH₃, CH₂CN
H
CH₃
CH₃
CH₃
H

I-1599
CH₂CH₃, CH₃
CH₃
CH₃
CH₃
CH₃
H

I-1600
CH₂CH₃, CH₂CH₃
CH₃
CH₃
CH₃
CH₃
H

I-1601
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
CH₃
H

I-1602
CH₂CH₃, C₃H₇
CH₃
CH₃
CH₃
CH₃
H

I-1603
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
CH₃
H

I-1604
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
CH₃
H

I-1605
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
CH₃
H

I-1606
CH₂CH₃, CH₂CN
CH₃
CH₃
CH₃
CH₃
H

I-1607
CH₂CH₃, CH₃
H
F
CH₃
CH₃
H

I-1608
CH₂CH₃, CH₂CH₃
H
F
CH₃
CH₃
H

I-1609
CH₂CH₃, CH(CH₃)₂
H
F
CH₃
CH₃
H

I-1610
CH₂CH₃, C₃H₇
H
F
CH₃
CH₃
H

I-1611
CH₂CH₃, C(═O)CH₃
H
F
CH₃
CH₃
H

I-1612
CH₂CH₃, C(═O)CH₂CH₃
H
F
CH₃
CH₃
H

I-1613
CH₂CH₃, C(═O)C₃H₇
H
F
CH₃
CH₃
H

I-1614
CH₂CH₃, CH₂CN
H
F
CH₃
CH₃
H

I-1615
CH₂CH₃, CH₃
CH₃
F
CH₃
CH₃
H

I-1616
CH₂CH₃, CH₂CH₃
CH₃
F
CH₃
CH₃
H

I-1617
CH₂CH₃, CH(CH₃)₂
CH₃
F
CH₃
CH₃
H

I-1618
CH₂CH₃, C₃H₇
CH₃
F
CH₃
CH₃
H

I-1619
CH₂CH₃, C(═O)CH₃
CH₃
F
CH₃
CH₃
H

I-1620
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
CH₃
H

I-1621
CH₂CH₃, C(═O)C₃H₇
CH₃
F
CH₃
CH₃
H

I-1622
CH₂CH₃, CH₂CN
CH₃
F
CH₃
CH₃
H

I-1623
CH₂CH₃, CH₃
H
F
F
H
H

I-1624
CH₂CH₃, CH₂CH₃
H
F
F
H
H

I-1625
CH₂CH₃, CH(CH₃)₂
H
F
F
H
H

I-1626
CH₂CH₃, C₃H₇
H
F
F
H
H

I-1627
CH₂CH₃, C(═O)CH₃
H
F
F
H
H

I-1628
CH₂CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-1629
CH₂CH₃, C(═O)C₃H₇
H
F
F
H
H

I-1630
CH₂CH₃, CH₂CN
H
F
F
H
H

I-1631
CH₂CH₃, CH₃
CH₃
F
F
H
H

I-1632
CH₂CH₃, CH₂CH₃
CH₃
F
F
H
H

I-1633
CH₂CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-1634
CH₂CH₃, C₃H₇
CH₃
F
F
H
H

I-1635
CH₂CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-1636
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-1637
CH₂CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-1638
CH₂CH₃, CH₂CN
CH₃
F
F
H
H

I-1639
CH₂CH₃, CH₃
H
C═O
CH₃
H

I-1640
CH₂CH₃, CH₂CH₃
H
C═O
CH₃
H

I-1641
CH₂CH₃, CH(CH₃)₂
H
C═O
CH₃
H

I-1642
CH₂CH₃, C₃H₇
H
C═O
CH₃
H

I-1643
CH₂CH₃, C(═O)CH₃
H
C═O
CH₃
H

I-1644
CH₂CH₃, C(═O)CH₂CH₃
H
C═O
CH₃
H

I-1645
CH₂CH₃, C(═O)C₃H₇
H
C═O
CH₃
H

I-1646
CH₂CH₃, CH₂CN
H
C═O
CH₃
H

I-1647
CH₂CH₃, CH₃
CH₃
C═O
CH₃
H

I-1648
CH₂CH₃, CH₂CH₃
CH₃
C═O
CH₃
H

I-1649
CH₂CH₃, CH(CH₃)₂
CH₃
C═O
CH₃
H

I-1650
CH₂CH₃, C₃H₇
CH₃
C═O
CH₃
H

I-1651
CH₂CH₃, C(═O)CH₃
CH₃
C═O
CH₃
H

I-1652
CH₂CH₃, C(═O)CH₂CH₃
CH₃
C═O
CH₃
H

I-1653
CH₂CH₃, C(═O)C₃H₇
CH₃
C═O
CH₃
H

I-1654
CH₂CH₃, CH₂CN
CH₃
C═O
CH₃
H

I-1655
CH₂CH₃, CH₃
H
H
H
F
H

I-1656
CH₂CH₃, CH₂CH₃
H
H
H
F
H

I-1657
CH₂CH₃, CH(CH₃)₂
H
H
H
F
H

I-1658
CH₂CH₃, C₃H₇
H
H
H
F
H

I-1659
CH₂CH₃, C(═O)CH₃
H
H
H
F
H

I-1660
CH₂CH₃, C(═O)CH₂CH₃
H
H
H
F
H

I-1661
CH₂CH₃, C(═O)C₃H₇
H
H
H
F
H

I-1662
CH₂CH₃, CH₂CN
H
H
H
F
H

I-1663
CH₂CH₃, CH₃
CH₃
H
H
F
H

I-1664
CH₂CH₃, CH₂CH₃
CH₃
H
H
F
H

I-1665
CH₂CH₃, CH(CH₃)₂
CH₃
H
H
F
H

I-1666
CH₂CH₃, C₃H₇
CH₃
H
H
F
H

I-1667
CH₂CH₃, C(═O)CH₃
CH₃
H
H
F
H

I-1668
CH₂CH₃, C(═O)CH₂CH₃
CH₃
H
H
F
H

I-1669
CH₂CH₃, C(═O)C₃H₇
CH₃
H
H
F
H

I-1670
CH₂CH₃, CH₂CN
CH₃
H
H
F
H

I-1671
CH₂CH₃, CH₃
H
CH₃
H
F
H

I-1672
CH₂CH₃, CH₂CH₃
H
CH₃
H
F
H

I-1673
CH₂CH₃, CH(CH₃)₂
H
CH₃
H
F
H

I-1674
CH₂CH₃, C₃H₇
H
CH₃
H
F
H

I-1675
CH₂CH₃, C(═O)CH₃
H
CH₃
H
F
H

I-1676
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
H
F
H

I-1677
CH₂CH₃, C(═O)C₃H₇
H
CH₃
H
F
H

I-1678
CH₂CH₃, CH₂CN
H
CH₃
H
F
H

I-1679
CH₂CH₃, CH₃
CH₃
CH₃
H
F
H

I-1680
CH₂CH₃, CH₂CH₃
CH₃
CH₃
H
F
H

I-1681
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
H
F
H

I-1682
CH₂CH₃, C₃H₇
CH₃
CH₃
H
F
H

I-1683
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
H
F
H

I-1684
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
F
H

I-1685
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
H
F
H

I-1686
CH₂CH₃, CH₂CN
CH₃
CH₃
H
F
H

I-1687
CH₂CH₃, CH₃
H
F
H
F
H

I-1688
CH₂CH₃, CH₂CH₃
H
F
H
F
H

I-1689
CH₂CH₃, CH(CH₃)₂
H
F
H
F
H

I-1690
CH₂CH₃, C₃H₇
H
F
H
F
H

I-1691
CH₂CH₃, C(═O)CH₃
H
F
H
F
H

I-1692
CH₂CH₃, C(═O)CH₂CH₃
H
F
H
F
H

I-1693
CH₂CH₃, C(═O)C₃H₇
H
F
H
F
H

I-1694
CH₂CH₃, CH₂CN
H
F
H
F
H

I-1695
CH₂CH₃, CH₃
CH₃
F
H
F
H

I-1696
CH₂CH₃, CH₂CH₃
CH₃
F
H
F
H

I-1697
CH₂CH₃, CH(CH₃)₂
CH₃
F
H
F
H

I-1698
CH₂CH₃, C₃H₇
CH₃
F
H
F
H

I-1699
CH₂CH₃, C(═O)CH₃
CH₃
F
H
F
H

I-1700
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
H
F
H

I-1701
CH₂CH₃, C(═O)C₃H₇
CH₃
F
H
F
H

I-1702
CH₂CH₃, CH₂CN
CH₃
F
H
F
H

I-1703
CH₂CH₃, CH₃
H
CH₃
CH₃
F
H

I-1704
CH₂CH₃, CH₂CH₃
H
CH₃
CH₃
F
H

I-1705
CH₂CH₃, CH(CH₃)₂
H
CH₃
CH₃
F
H

I-1706
CH₂CH₃, C₃H₇
H
CH₃
CH₃
F
H

I-1707
CH₂CH₃, C(═O)CH₃
H
CH₃
CH₃
F
H

I-1708
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
F
H

I-1709
CH₂CH₃, C(═O)C₃H₇
H
CH₃
CH₃
F
H

I-1710
CH₂CH₃, CH₂CN
H
CH₃
CH₃
F
H

I-1711
CH₂CH₃, CH₃
CH₃
CH₃
CH₃
F
H

I-1712
CH₂CH₃, CH₂CH₃
CH₃
CH₃
CH₃
F
H

I-1713
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
F
H

I-1714
CH₂CH₃, C₃H₇
CH₃
CH₃
CH₃
F
H

I-1715
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
F
H

I-1716
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
H

I-1717
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
H

I-1718
CH₂CH₃, CH₂CN
CH₃
CH₃
CH₃
F
H

I-1719
CH₂CH₃, CH₃
H
F
CH₃
F
H

I-1720
CH₂CH₃, CH₂CH₃
H
F
CH₃
F
H

I-1721
CH₂CH₃, CH(CH₃)₂
H
F
CH₃
F
H

I-1722
CH₂CH₃, C₃H₇
H
F
CH₃
F
H

I-1723
CH₂CH₃, C(═O)CH₃
H
F
CH₃
F
H

I-1724
CH₂CH₃, C(═O)CH₂CH₃
H
F
CH₃
F
H

I-1725
CH₂CH₃, C(═O)C₃H₇
H
F
CH₃
F
H

I-1726
CH₂CH₃, CH₂CN
H
F
CH₃
F
H

I-1727
CH₂CH₃, CH₃
CH₃
F
CH₃
F
H

I-1728
CH₂CH₃, CH₂CH₃
CH₃
F
CH₃
F
H

I-1729
CH₂CH₃, CH(CH₃)₂
CH₃
F
CH₃
F
H

I-1730
CH₂CH₃, C₃H₇
CH₃
F
CH₃
F
H

I-1731
CH₂CH₃, C(═O)CH₃
CH₃
F
CH₃
F
H

I-1732
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
F
H

I-1733
CH₂CH₃, C(═O)C₃H₇
CH₃
F
CH₃
F
H

I-1734
CH₂CH₃, CH₂CN
CH₃
F
CH₃
F
H

I-1735
CH₂CH₃, CH₃
H
F
F
H
H

I-1736
CH₂CH₃, CH₂CH₃
H
F
F
H
H

I-1737
CH₂CH₃, CH(CH₃)₂
H
F
F
H
H

I-1738
CH₂CH₃, C₃H₇
H
F
F
H
H

I-1739
CH₂CH₃, C(═O)CH₃
H
F
F
H
H

I-1740
CH₂CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-1741
CH₂CH₃, C(═O)C₃H₇
H
F
F
H
H

I-1742
CH₂CH₃, CH₂CN
H
F
F
H
H

I-1743
CH₂CH₃, CH₃
CH₃
F
F
H
H

I-1744
CH₂CH₃, CH₂CH₃
CH₃
F
F
H
H

I-1745
CH₂CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-1746
CH₂CH₃, C₃H₇
CH₃
F
F
H
H

I-1747
CH₂CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-1748
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-1749
CH₂CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-1750
CH₂CH₃, CH₂CN
CH₃
F
F
H
H

I-1751
CH₂CH₃, CH₃
H
C═O
F
H

I-1752
CH₂CH₃, CH₂CH₃
H
C═O
F
H

I-1753
CH₂CH₃, CH(CH₃)₂
H
C═O
F
H

I-1754
CH₂CH₃, C₃H₇
H
C═O
F
H

I-1755
CH₂CH₃, C(═O)CH₃
H
C═O
F
H

I-1756
CH₂CH₃, C(═O)CH₂CH₃
H
C═O
F
H

I-1757
CH₂CH₃, C(═O)C₃H₇
H
C═O
F
H

I-1758
CH₂CH₃, CH₂CN
H
C═O
F
H

I-1759
CH₂CH₃, CH₃
CH₃
C═O
F
H

I-1760
CH₂CH₃, CH₂CH₃
CH₃
C═O
F
H

I-1761
CH₂CH₃, CH(CH₃)₂
CH₃
C═O
F
H

I-1762
CH₂CH₃, C₃H₇
CH₃
C═O
F
H

I-1763
CH₂CH₃, C(═O)CH₃
CH₃
C═O
F
H

I-1764
CH₂CH₃, C(═O)CH₂CH₃
CH₃
C═O
F
H

I-1765
CH₂CH₃, C(═O)C₃H₇
CH₃
C═O
F
H

I-1766
CH₂CH₃, CH₂CN
CH₃
C═O
F
H

I-1767
CH₂CH₃, CH₃
H
H
H
CH₃
CH₃

I-1768
CH₂CH₃, CH₂CH₃
H
H
H
CH₃
CH₃

I-1769
CH₂CH₃, CH(CH₃)₂
H
H
H
CH₃
CH₃

I-1770
CH₂CH₃, C₃H₇
H
H
H
CH₃
CH₃

I-1771
CH₂CH₃, C(═O)CH₃
H
H
H
CH₃
CH₃

I-1772
CH₂CH₃, C(═O)CH₂CH₃
H
H
H
CH₃
CH₃

I-1773
CH₂CH₃, C(═O)C₃H₇
H
H
H
CH₃
CH₃

I-1774
CH₂CH₃, CH₂CN
H
H
H
CH₃
CH₃

I-1775
CH₂CH₃, CH₃
CH₃
H
H
CH₃
CH₃

I-1776
CH₂CH₃, CH₂CH₃
CH₃
H
H
CH₃
CH₃

I-1777
CH₂CH₃, CH(CH₃)₂
CH₃
H
H
CH₃
CH₃

I-1778
CH₂CH₃, C₃H₇
CH₃
H
H
CH₃
CH₃

I-1779
CH₂CH₃, C(═O)CH₃
CH₃
H
H
CH₃
CH₃

I-1780
CH₂CH₃, C(═O)CH₂CH₃
CH₃
H
H
CH₃
CH₃

I-1781
CH₂CH₃, C(═O)C₃H₇
CH₃
H
H
CH₃
CH₃

I-1782
CH₂CH₃, CH₂CN
CH₃
H
H
CH₃
CH₃

I-1783
CH₂CH₃, CH₃
H
CH₃
H
CH₃
CH₃

I-1784
CH₂CH₃, CH₂CH₃
H
CH₃
H
CH₃
CH₃

I-1785
CH₂CH₃, CH(CH₃)₂
H
CH₃
H
CH₃
CH₃

I-1786
CH₂CH₃, C₃H₇
H
CH₃
H
CH₃
CH₃

I-1787
CH₂CH₃, C(═O)CH₃
H
CH₃
H
CH₃
CH₃

I-1788
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
H
CH₃
CH₃

I-1789
CH₂CH₃, C(═O)C₃H₇
H
CH₃
H
CH₃
CH₃

I-1790
CH₂CH₃, CH₂CN
H
CH₃
H
CH₃
CH₃

I-1791
CH₂CH₃, CH₃
CH₃
CH₃
H
CH₃
CH₃

I-1792
CH₂CH₃, CH₂CH₃
CH₃
CH₃
H
CH₃
CH₃

I-1793
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
H
CH₃
CH₃

I-1794
CH₂CH₃, C₃H₇
CH₃
CH₃
H
CH₃
CH₃

I-1795
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
H
CH₃
CH₃

I-1796
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
CH₃
CH₃

I-1797
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
H
CH₃
CH₃

I-1798
CH₂CH₃, CH₂CN
CH₃
CH₃
H
CH₃
CH₃

I-1799
CH₂CH₃, CH₃
H
F
H
CH₃
CH₃

I-1800
CH₂CH₃, CH₂CH₃
H
F
H
CH₃
CH₃

I-1801
CH₂CH₃, CH(CH₃)₂
H
F
H
CH₃
CH₃

I-1802
CH₂CH₃, C₃H₇
H
F
H
CH₃
CH₃

I-1803
CH₂CH₃, C(═O)CH₃
H
F
H
CH₃
CH₃

I-1804
CH₂CH₃, C(═O)CH₂CH₃
H
F
H
CH₃
CH₃

I-1805
CH₂CH₃, C(═O)C₃H₇
H
F
H
CH₃
CH₃

I-1806
CH₂CH₃, CH₂CN
H
F
H
CH₃
CH₃

I-1807
CH₂CH₃, CH₃
CH₃
F
H
CH₃
CH₃

I-1808
CH₂CH₃, CH₂CH₃
CH₃
F
H
CH₃
CH₃

I-1809
CH₂CH₃, CH(CH₃)₂
CH₃
F
H
CH₃
CH₃

I-1810
CH₂CH₃, C₃H₇
CH₃
F
H
CH₃
CH₃

I-1811
CH₂CH₃, C(═O)CH₃
CH₃
F
H
CH₃
CH₃

I-1812
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
H
CH₃
CH₃

I-1813
CH₂CH₃, C(═O)C₃H₇
CH₃
F
H
CH₃
CH₃

I-1814
CH₂CH₃, CH₂CN
CH₃
F
H
CH₃
CH₃

I-1815
CH₂CH₃, CH₃
H
CH₃
CH₃
CH₃
CH₃

I-1816
CH₂CH₃, CH₂CH₃
H
CH₃
CH₃
CH₃
CH₃

I-1817
CH₂CH₃, CH(CH₃)₂
H
CH₃
CH₃
CH₃
CH₃

I-1818
CH₂CH₃, C₃H₇
H
CH₃
CH₃
CH₃
CH₃

I-1819
CH₂CH₃, C(═O)CH₃
H
CH₃
CH₃
CH₃
CH₃

I-1820
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
CH₃
CH₃

I-1821
CH₂CH₃, C(═O)C₃H₇
H
CH₃
CH₃
CH₃
CH₃

I-1822
CH₂CH₃, CH₂CN
H
CH₃
CH₃
CH₃
CH₃

I-1823
CH₂CH₃, CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-1824
CH₂CH₃, CH₂CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-1825
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
CH₃
CH₃

I-1826
CH₂CH₃, C₃H₇
CH₃
CH₃
CH₃
CH₃
CH₃

I-1827
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-1828
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
CH₃
CH₃

I-1829
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
CH₃
CH₃

I-1830
CH₂CH₃, CH₂CN
CH₃
CH₃
CH₃
CH₃
CH₃

I-1831
CH₂CH₃, CH₃
H
F
CH₃
CH₃
CH₃

I-1832
CH₂CH₃, CH₂CH₃
H
F
CH₃
CH₃
CH₃

I-1833
CH₂CH₃, CH(CH₃)₂
H
F
CH₃
CH₃
CH₃

I-1834
CH₂CH₃, C₃H₇
H
F
CH₃
CH₃
CH₃

I-1835
CH₂CH₃, C(═O)CH₃
H
F
CH₃
CH₃
CH₃

I-1836
CH₂CH₃, C(═O)CH₂CH₃
H
F
CH₃
CH₃
CH₃

I-1837
CH₂CH₃, C(═O)C₃H₇
H
F
CH₃
CH₃
CH₃

I-1838
CH₂CH₃, CH₂CN
H
F
CH₃
CH₃
CH₃

I-1839
CH₂CH₃, CH₃
CH₃
F
CH₃
CH₃
CH₃

I-1840
CH₂CH₃, CH₂CH₃
CH₃
F
CH₃
CH₃
CH₃

I-1841
CH₂CH₃, CH(CH₃)₂
CH₃
F
CH₃
CH₃
CH₃

I-1842
CH₂CH₃, C₃H₇
CH₃
F
CH₃
CH₃
CH₃

I-1843
CH₂CH₃, C(═O)CH₃
CH₃
F
CH₃
CH₃
CH₃

I-1844
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
CH₃
CH₃

I-1845
CH₂CH₃, C(═O)C₃H₇
CH₃
F
CH₃
CH₃
CH₃

I-1846
CH₂CH₃, CH₂CN
CH₃
F
CH₃
CH₃
CH₃

I-1847
CH₂CH₃, CH₃
H
F
F
H
H

I-1848
CH₂CH₃, CH₂CH₃
H
F
F
H
H

I-1849
CH₂CH₃, CH(CH₃)₂
H
F
F
H
H

I-1850
CH₂CH₃, C₃H₇
H
F
F
H
H

I-1851
CH₂CH₃, C(═O)CH₃
H
F
F
H
H

I-1852
CH₂CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-1853
CH₂CH₃, C(═O)C₃H₇
H
F
F
H
H

I-1854
CH₂CH₃, CH₂CN
H
F
F
H
H

I-1855
CH₂CH₃, CH₃
CH₃
F
F
H
H

I-1856
CH₂CH₃, CH₂CH₃
CH₃
F
F
H
H

I-1857
CH₂CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-1858
CH₂CH₃, C₃H₇
CH₃
F
F
H
H

I-1859
CH₂CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-1860
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-1861
CH₂CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-1862
CH₂CH₃, CH₂CN
CH₃
F
F
H
H

I-1863
CH₂CH₃, CH₃
H
C═O
CH₃
CH₃

I-1864
CH₂CH₃, CH₂CH₃
H
C═O
CH₃
CH₃

I-1865
CH₂CH₃, CH(CH₃)₂
H
C═O
CH₃
CH₃

I-1866
CH₂CH₃, C₃H₇
H
C═O
CH₃
CH₃

I-1867
CH₂CH₃, C(═O)CH₃
H
C═O
CH₃
CH₃

I-1868
CH₂CH₃, C(═O)CH₂CH₃
H
C═O
CH₃
CH₃

I-1869
CH₂CH₃, C(═O)C₃H₇
H
C═O
CH₃
CH₃

I-1870
CH₂CH₃, CH₂CN
H
C═O
CH₃
CH₃

I-1871
CH₂CH₃, CH₃
CH₃
C═O
CH₃
CH₃

I-1872
CH₂CH₃, CH₂CH₃
CH₃
C═O
CH₃
CH₃

I-1873
CH₂CH₃, CH(CH₃)₂
CH₃
C═O
CH₃
CH₃

I-1874
CH₂CH₃, C₃H₇
CH₃
C═O
CH₃
CH₃

I-1875
CH₂CH₃, C(═O)CH₃
CH₃
C═O
CH₃
CH₃

I-1876
CH₂CH₃, C(═O)CH₂CH₃
CH₃
C═O
CH₃
CH₃

I-1877
CH₂CH₃, C(═O)C₃H₇
CH₃
C═O
CH₃
CH₃

I-1878
CH₂CH₃, CH₂CN
CH₃
C═O
CH₃
CH₃

I-1879
CH₂CH₃, CH₃
H
H
H
F
CH₃

I-1880
CH₂CH₃, CH₂CH₃
H
H
H
F
CH₃

I-1881
CH₂CH₃, CH(CH₃)₂
H
H
H
F
CH₃

I-1882
CH₂CH₃, C₃H₇
H
H
H
F
CH₃

I-1883
CH₂CH₃, C(═O)CH₃
H
H
H
F
CH₃

I-1884
CH₂CH₃, C(═O)CH₂CH₃
H
H
H
F
CH₃

I-1885
CH₂CH₃, C(═O)C₃H₇
H
H
H
F
CH₃

I-1886
CH₂CH₃, CH₂CN
H
H
H
F
CH₃

I-1887
CH₂CH₃, CH₃
CH₃
H
H
F
CH₃

I-1888
CH₂CH₃, CH₂CH₃
CH₃
H
H
F
CH₃

I-1889
CH₂CH₃, CH(CH₃)₂
CH₃
H
H
F
CH₃

I-1890
CH₂CH₃, C₃H₇
CH₃
H
H
F
CH₃

I-1891
CH₂CH₃, C(═O)CH₃
CH₃
H
H
F
CH₃

I-1892
CH₂CH₃, C(═O)CH₂CH₃
CH₃
H
H
F
CH₃

I-1893
CH₂CH₃, C(═O)C₃H₇
CH₃
H
H
F
CH₃

I-1894
CH₂CH₃, CH₂CN
CH₃
H
H
F
CH₃

I-1895
CH₂CH₃, CH₃
H
CH₃
H
F
CH₃

I-1896
CH₂CH₃, CH₂CH₃
H
CH₃
H
F
CH₃

I-1897
CH₂CH₃, CH(CH₃)₂
H
CH₃
H
F
CH₃

I-1898
CH₂CH₃, C₃H₇
H
CH₃
H
F
CH₃

I-1899
CH₂CH₃, C(═O)CH₃
H
CH₃
H
F
CH₃

I-1900
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
H
F
CH₃

I-1901
CH₂CH₃, C(═O)C₃H₇
H
CH₃
H
F
CH₃

I-1902
CH₂CH₃, CH₂CN
H
CH₃
H
F
CH₃

I-1903
CH₂CH₃, CH₃
CH₃
CH₃
H
F
CH₃

I-1904
CH₂CH₃, CH₂CH₃
CH₃
CH₃
H
F
CH₃

I-1905
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
H
F
CH₃

I-1906
CH₂CH₃, C₃H₇
CH₃
CH₃
H
F
CH₃

I-1907
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
H
F
CH₃

I-1908
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
F
CH₃

I-1909
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
H
F
CH₃

I-1910
CH₂CH₃, CH₂CN
CH₃
CH₃
H
F
CH₃

I-1911
CH₂CH₃, CH₃
H
F
H
F
CH₃

I-1912
CH₂CH₃, CH₂CH₃
H
F
H
F
CH₃

I-1913
CH₂CH₃, CH(CH₃)₂
H
F
H
F
CH₃

I-1914
CH₂CH₃, C₃H₇
H
F
H
F
CH₃

I-1915
CH₂CH₃, C(═O)CH₃
H
F
H
F
CH₃

I-1916
CH₂CH₃, C(═O)CH₂CH₃
H
F
H
F
CH₃

I-1917
CH₂CH₃, C(═O)C₃H₇
H
F
H
F
CH₃

I-1918
CH₂CH₃, CH₂CN
H
F
H
F
CH₃

I-1919
CH₂CH₃, CH₃
CH₃
F
H
F
CH₃

I-1920
CH₂CH₃, CH₂CH₃
CH₃
F
H
F
CH₃

I-1921
CH₂CH₃, CH(CH₃)₂
CH₃
F
H
F
CH₃

I-1922
CH₂CH₃, C₃H₇
CH₃
F
H
F
CH₃

I-1923
CH₂CH₃, C(═O)CH₃
CH₃
F
H
F
CH₃

I-1924
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
H
F
CH₃

I-1925
CH₂CH₃, C(═O)C₃H₇
CH₃
F
H
F
CH₃

I-1926
CH₂CH₃, CH₂CN
CH₃
F
H
F
CH₃

I-1927
CH₂CH₃, CH₃
H
CH₃
CH₃
F
CH₃

I-1928
CH₂CH₃, CH₂CH₃
H
CH₃
CH₃
F
CH₃

I-1929
CH₂CH₃, CH(CH₃)₂
H
CH₃
CH₃
F
CH₃

I-1930
CH₂CH₃, C₃H₇
H
CH₃
CH₃
F
CH₃

I-1931
CH₂CH₃, C(═O)CH₃
H
CH₃
CH₃
F
CH₃

I-1932
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
F
CH₃

I-1933
CH₂CH₃, C(═O)C₃H₇
H
CH₃
CH₃
F
CH₃

I-1934
CH₂CH₃, CH₂CN
H
CH₃
CH₃
F
CH₃

I-1935
CH₂CH₃, CH₃
CH₃
CH₃
CH₃
F
CH₃

I-1936
CH₂CH₃, CH₂CH₃
CH₃
CH₃
CH₃
F
CH₃

I-1937
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
F
CH₃

I-1938
CH₂CH₃, C₃H₇
CH₃
CH₃
CH₃
F
CH₃

I-1939
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
F
CH₃

I-1940
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
CH₃

I-1941
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
CH₃

I-1942
CH₂CH₃, CH₂CN
CH₃
CH₃
CH₃
F
CH₃

I-1943
CH₂CH₃, CH₃
H
F
CH₃
F
CH₃

I-1944
CH₂CH₃, CH₂CH₃
H
F
CH₃
F
CH₃

I-1945
CH₂CH₃, CH(CH₃)₂
H
F
CH₃
F
CH₃

I-1946
CH₂CH₃, C₃H₇
H
F
CH₃
F
CH₃

I-1947
CH₂CH₃, C(═O)CH₃
H
F
CH₃
F
CH₃

I-1948
CH₂CH₃, C(═O)CH₂CH₃
H
F
CH₃
F
CH₃

I-1949
CH₂CH₃, C(═O)C₃H₇
H
F
CH₃
F
CH₃

I-1950
CH₂CH₃, CH₂CN
H
F
CH₃
F
CH₃

I-1951
CH₂CH₃, CH₃
CH₃
F
CH₃
F
CH₃

I-1952
CH₂CH₃, CH₂CH₃
CH₃
F
CH₃
F
CH₃

I-1953
CH₂CH₃, CH(CH₃)₂
CH₃
F
CH₃
F
CH₃

I-1954
CH₂CH₃, C₃H₇
CH₃
F
CH₃
F
CH₃

I-1955
CH₂CH₃, C(═O)CH₃
CH₃
F
CH₃
F
CH₃

I-1956
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
F
CH₃

I-1957
CH₂CH₃, C(═O)C₃H₇
CH₃
F
CH₃
F
CH₃

I-1958
CH₂CH₃, CH₂CN
CH₃
F
CH₃
F
CH₃

I-1959
CH₂CH₃, CH₃
H
F
F
H
H

I-1960
CH₂CH₃, CH₂CH₃
H
F
F
H
H

I-1961
CH₂CH₃, CH(CH₃)₂
H
F
F
H
H

I-1962
CH₂CH₃, C₃H₇
H
F
F
H
H

I-1963
CH₂CH₃, C(═O)CH₃
H
F
F
H
H

I-1964
CH₂CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-1965
CH₂CH₃, C(═O)C₃H₇
H
F
F
H
H

I-1966
CH₂CH₃, CH₂CN
H
F
F
H
H

I-1967
CH₂CH₃, CH₃
CH₃
F
F
H
H

I-1968
CH₂CH₃, CH₂CH₃
CH₃
F
F
H
H

I-1969
CH₂CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-1970
CH₂CH₃, C₃H₇
CH₃
F
F
H
H

I-1971
CH₂CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-1972
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-1973
CH₂CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-1974
CH₂CH₃, CH₂CN
CH₃
F
F
H
H

I-1975
CH₂CH₃, CH₃
H
C═O
F
CH₃

I-1976
CH₂CH₃, CH₂CH₃
H
C═O
F
CH₃

I-1977
CH₂CH₃, CH(CH₃)₂
H
C═O
F
CH₃

I-1978
CH₂CH₃, C₃H₇
H
C═O
F
CH₃

I-1979
CH₂CH₃, C(═O)CH₃
H
C═O
F
CH₃

I-1980
CH₂CH₃, C(═O)CH₂CH₃
H
C═O
F
CH₃

I-1981
CH₂CH₃, C(═O)C₃H₇
H
C═O
F
CH₃

I-1982
CH₂CH₃, CH₂CN
H
C═O
F
CH₃

I-1983
CH₂CH₃, CH₃
CH₃
C═O
F
CH₃

I-1984
CH₂CH₃, CH₂CH₃
CH₃
C═O
F
CH₃

I-1985
CH₂CH₃, CH(CH₃)₂
CH₃
C═O
F
CH₃

I-1986
CH₂CH₃, C₃H₇
CH₃
C═O
F
CH₃

I-1987
CH₂CH₃, C(═O)CH₃
CH₃
C═O
F
CH₃

I-1988
CH₂CH₃, C(═O)CH₂CH₃
CH₃
C═O
F
CH₃

I-1989
CH₂CH₃, C(═O)C₃H₇
CH₃
C═O
F
CH₃

I-1990
CH₂CH₃, CH₂CN
CH₃
C═O
F
CH₃

I-1991
CH₂CH₃, CH₃
H
H
H
F
F

I-1992
CH₂CH₃, CH₂CH₃
H
H
H
F
F

I-1993
CH₂CH₃, CH(CH₃)₂
H
H
H
F
F

I-1994
CH₂CH₃, C₃H₇
H
H
H
F
F

I-1995
CH₂CH₃, C(═O)CH₃
H
H
H
F
F

I-1996
CH₂CH₃, C(═O)CH₂CH₃
H
H
H
F
F

I-1997
CH₂CH₃, C(═O)C₃H₇
H
H
H
F
F

I-1998
CH₂CH₃, CH₂CN
H
H
H
F
F

I-1999
CH₂CH₃, CH₃
CH₃
H
H
F
F

I-2000
CH₂CH₃, CH₂CH₃
CH₃
H
H
F
F

I-2001
CH₂CH₃, CH(CH₃)₂
CH₃
H
H
F
F

I-2002
CH₂CH₃, C₃H₇
CH₃
H
H
F
F

I-2003
CH₂CH₃, C(═O)CH₃
CH₃
H
H
F
F

I-2004
CH₂CH₃, C(═O)CH₂CH₃
CH₃
H
H
F
F

I-2005
CH₂CH₃, C(═O)C₃H₇
CH₃
H
H
F
F

I-2006
CH₂CH₃, CH₂CN
CH₃
H
H
F
F

I-2007
CH₂CH₃, CH₃
H
CH₃
H
F
F

I-2008
CH₂CH₃, CH₂CH₃
H
CH₃
H
F
F

I-2009
CH₂CH₃, CH(CH₃)₂
H
CH₃
H
F
F

I-2010
CH₂CH₃, C₃H₇
H
CH₃
H
F
F

I-2011
CH₂CH₃, C(═O)CH₃
H
CH₃
H
F
F

I-2012
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
H
F
F

I-2013
CH₂CH₃, C(═O)C₃H₇
H
CH₃
H
F
F

I-2014
CH₂CH₃, CH₂CN
H
CH₃
H
F
F

I-2015
CH₂CH₃, CH₃
CH₃
CH₃
H
F
F

I-2016
CH₂CH₃, CH₂CH₃
CH₃
CH₃
H
F
F

I-2017
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
H
F
F

I-2018
CH₂CH₃, C₃H₇
CH₃
CH₃
H
F
F

I-2019
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
H
F
F

I-2020
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
H
F
F

I-2021
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
H
F
F

I-2022
CH₂CH₃, CH₂CN
CH₃
CH₃
H
F
F

I-2023
CH₂CH₃, CH₃
H
F
H
F
F

I-2024
CH₂CH₃, CH₂CH₃
H
F
H
F
F

I-2025
CH₂CH₃, CH(CH₃)₂
H
F
H
F
F

I-2026
CH₂CH₃, C₃H₇
H
F
H
F
F

I-2027
CH₂CH₃, C(═O)CH₃
H
F
H
F
F

I-2028
CH₂CH₃, C(═O)CH₂CH₃
H
F
H
F
F

I-2029
CH₂CH₃, C(═O)C₃H₇
H
F
H
F
F

I-2030
CH₂CH₃, CH₂CN
H
F
H
F
F

I-2031
CH₂CH₃, CH₃
CH₃
F
H
F
F

I-2032
CH₂CH₃, CH₂CH₃
CH₃
F
H
F
F

I-2033
CH₂CH₃, CH(CH₃)₂
CH₃
F
H
F
F

I-2034
CH₂CH₃, C₃H₇
CH₃
F
H
F
F

I-2035
CH₂CH₃, C(═O)CH₃
CH₃
F
H
F
F

I-2036
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
H
F
F

I-2037
CH₂CH₃, C(═O)C₃H₇
CH₃
F
H
F
F

I-2038
CH₂CH₃, CH₂CN
CH₃
F
H
F
F

I-2039
CH₂CH₃, CH₃
H
CH₃
CH₃
F
F

I-2040
CH₂CH₃, CH₂CH₃
H
CH₃
CH₃
F
F

I-2041
CH₂CH₃, CH(CH₃)₂
H
CH₃
CH₃
F
F

I-2042
CH₂CH₃, C₃H₇
H
CH₃
CH₃
F
F

I-2043
CH₂CH₃, C(═O)CH₃
H
CH₃
CH₃
F
F

I-2044
CH₂CH₃, C(═O)CH₂CH₃
H
CH₃
CH₃
F
F

I-2045
CH₂CH₃, C(═O)C₃H₇
H
CH₃
CH₃
F
F

I-2046
CH₂CH₃, CH₂CN
H
CH₃
CH₃
F
F

I-2047
CH₂CH₃, CH₃
CH₃
CH₃
CH₃
F
F

I-2048
CH₂CH₃, CH₂CH₃
CH₃
CH₃
CH₃
F
F

I-2049
CH₂CH₃, CH(CH₃)₂
CH₃
CH₃
CH₃
F
F

I-2050
CH₂CH₃, C₃H₇
CH₃
CH₃
CH₃
F
F

I-2051
CH₂CH₃, C(═O)CH₃
CH₃
CH₃
CH₃
F
F

I-2052
CH₂CH₃, C(═O)CH₂CH₃
CH₃
CH₃
CH₃
F
F

I-2053
CH₂CH₃, C(═O)C₃H₇
CH₃
CH₃
CH₃
F
F

I-2054
CH₂CH₃, CH₂CN
CH₃
CH₃
CH₃
F
F

I-2055
CH₂CH₃, CH₃
H
F
CH₃
F
F

I-2056
CH₂CH₃, CH₂CH₃
H
F
CH₃
F
F

I-2057
CH₂CH₃, CH(CH₃)₂
H
F
CH₃
F
F

I-2058
CH₂CH₃, C₃H₇
H
F
CH₃
F
F

I-2059
CH₂CH₃, C(═O)CH₃
H
F
CH₃
F
F

I-2060
CH₂CH₃, C(═O)CH₂CH₃
H
F
CH₃
F
F

I-2061
CH₂CH₃, C(═O)C₃H₇
H
F
CH₃
F
F

I-2062
CH₂CH₃, CH₂CN
H
F
CH₃
F
F

I-2063
CH₂CH₃, CH₃
CH₃
F
CH₃
F
F

I-2064
CH₂CH₃, CH₂CH₃
CH₃
F
CH₃
F
F

I-2065
CH₂CH₃, CH(CH₃)₂
CH₃
F
CH₃
F
F

I-2066
CH₂CH₃, C₃H₇
CH₃
F
CH₃
F
F

I-2067
CH₂CH₃, C(═O)CH₃
CH₃
F
CH₃
F
F

I-2068
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
CH₃
F
F

I-2069
CH₂CH₃, C(═O)C₃H₇
CH₃
F
CH₃
F
F

I-2070
CH₂CH₃, CH₂CN
CH₃
F
CH₃
F
F

I-2071
CH₂CH₃, CH₃
H
F
F
H
H

I-2072
CH₂CH₃, CH₂CH₃
H
F
F
H
H

I-2073
CH₂CH₃, CH(CH₃)₂
H
F
F
H
H

I-2074
CH₂CH₃, C₃H₇
H
F
F
H
H

I-2075
CH₂CH₃, C(═O)CH₃
H
F
F
H
H

I-2076
CH₂CH₃, C(═O)CH₂CH₃
H
F
F
H
H

I-2077
CH₂CH₃, C(═O)C₃H₇
H
F
F
H
H

I-2078
CH₂CH₃, CH₂CN
H
F
F
H
H

I-2079
CH₂CH₃, CH₃
CH₃
F
F
H
H

I-2080
CH₂CH₃, CH₂CH₃
CH₃
F
F
H
H

I-2081
CH₂CH₃, CH(CH₃)₂
CH₃
F
F
H
H

I-2082
CH₂CH₃, C₃H₇
CH₃
F
F
H
H

I-2083
CH₂CH₃, C(═O)CH₃
CH₃
F
F
H
H

I-2084
CH₂CH₃, C(═O)CH₂CH₃
CH₃
F
F
H
H

I-2085
CH₂CH₃, C(═O)C₃H₇
CH₃
F
F
H
H

I-2086
CH₂CH₃, CH₂CN
CH₃
F
F
H
H

I-2087
CH₂CH₃, CH₃
H
C═O
F
F

I-2088
CH₂CH₃, CH₂CH₃
H
C═O
F
F

I-2089
CH₂CH₃, CH(CH₃)₂
H
C═O
F
F

I-2090
CH₂CH₃, C₃H₇
H
C═O
F
F

I-2091
CH₂CH₃, C(═O)CH₃
H
C═O
F
F

I-2092
CH₂CH₃, C(═O)CH₂CH₃
H
C═O
F
F

I-2093
CH₂CH₃, C(═O)C₃H₇
H
C═O
F
F

I-2094
CH₂CH₃, CH₂CN
H
C═O
F
F

I-2095
CH₂CH₃, CH₃
CH₃
C═O
F
F

I-2096
CH₂CH₃, CH₂CH₃
CH₃
C═O
F
F

I-2097
CH₂CH₃, CH(CH₃)₂
CH₃
C═O
F
F

I-2098
CH₂CH₃, C₃H₇
CH₃
C═O
F
F

I-2099
CH₂CH₃, C(═O)CH₃
CH₃
C═O
F
F

I-2100
CH₂CH₃, C(═O)CH₂CH₃
CH₃
C═O
F
F

I-2101
CH₂CH₃, C(═O)C₃H₇
CH₃
C═O
F
F

I-2102
CH₂CH₃, CH₂CN
CH₃
C═O
F
F

The compounds of the formula I can be prepared according to methods or in analogy to methods that are described in the prior art. The synthesis takes advantage of starting materials that are commercially available or may be prepared according to conventional procedures starting from readily available compounds. Compounds of type I are typically prepared as described before, for example in WO 2003055866 and WO 2009074950. A skilled person will realize that compounds of type II can be reacted with the appropriate amine to give compounds of type I in the presence of a base, preferably pyridine in an organic solvent, preferably an aromatic hydrocarbon compound. It is preferred to conduct the reaction at elevated temperature, preferably between 60 and 100° C.

[Image Omitted]

Compounds of type II can be prepared as described before, for example in WO 2013008162 from compounds of formula III.

[Image Omitted]

For example, compounds of the formula III can be prepared by reacting amidines of type IV with trifluoroacetic anhydride in an organic solvent, preferably an ethereal solvent at temperatures between 0° C. and 100° C., preferably at room temperature, as previously described in WO 2013008162.

[Image Omitted]

Compounds of type IV can be accessed from the respective nitrile by reacting said compounds of type V with hydroxylamine (or its HCl salt) in an organic solvent and in the presence of a base (for precedents see for example WO 2009074950, WO 2006013104, EP 1932843). Preferably, an alcoholic solvent and an inorganic base are used, most preferably ethanol and potassium carbonate. If appropriate water may be added to enhance solubility of the reactants. The reaction is best performed at elevated temperatures, most preferably in the range between 60° C. and 80° C.

[Image Omitted]

The compounds of the formula I or compositions comprising said compounds according to the invention and the mixtures comprising said compounds and compositions, respectively, are suitable as fungicides. They are distinguished by an outstanding effectiveness against a broad spectrum of phytopathogenic fungi, including soil-borne fungi, which derive especially from the following classes or are closely related to any of them: Ascomycota (Ascomycetes), for example, but not limited to the genus Cocholiobolus, Colletotrichum, Fusarium, Microdochium, Penicillium, Phoma, Magnaporte, Zymoseptoria, and Pseudocercosporella; Basdiomycota (Basidiomycetes), for example, but not limited to the genus Phakospora, Puccinia, Rhizoctonia, Sphacelotheca, Tilletia, Typhula, and Ustilago; Chytridiomycota (Chytridiomycetes), for example, but not limited to the genus Chytridiales, and Synchytrium; Deuteromycetes (syn. Fungi imperfecti), for example, but not limited to the genus Ascochyta, Dip/odia, Erysiphe, Fusarium, Phomopsis, and Pyrenophora; Peronosporomycetes (syn. Oomycetes), for example but not limited to the genus Peronospora, Pythium, Phytophthora; Plasmodiophoromycetes, for example but not limited to the genus Plasmodiophora; Zygomycetes, for example, but not limited to the genus Rhizopus.

Some of the compounds of the formula I and the compositions according to the invention are systemically effective and they can be used in crop protection as foliar fungicides, fungicides for seed dressing and soil fungicides. Moreover, they are suitable for controlling harmful fungi, which inter alia occur in wood or roots of plants.

The compounds I and the compositions according to the invention are particularly important in the control of a multitude of phytopathogenic fungi on various cultivated plants, such as cereals, e.g. wheat, rye, barley, triticale, oats or rice; beet, e.g. sugar beet or fodder beet; fruits, such as pomes, stone fruits or soft fruits, e.g. apples, pears, plums, peaches, almonds, cherries, strawberries, raspberries, blackberries or gooseberries; leguminous plants, such as lentils, peas, alfalfa or soybeans; oil plants, such as rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palms, ground nuts or soybeans; cucurbits, such as squashes, cucumber or melons; fiber plants, such as cotton, flax, hemp or jute; citrus fruit, such as oranges, lemons, grapefruits or mandarins; vegetables, such as spinach, lettuce, asparagus, cabbages, carrots, onions, tomatoes, potatoes, cucurbits or paprika; lauraceous plants, such as avocados, cinnamon or camphor; energy and raw material plants, such as corn, soybean, rape, sugar cane or oil palm; corn; tobacco; nuts; coffee; tea; bananas; vines (table grapes and grape juice grape vines); hop; turf; sweet leaf (also called Stevia); natural rubber plants or ornamental and forestry plants, such as flowers, shrubs, broad-leaved trees or evergreens, e.g. conifers; and on the plant propagation material, such as seeds, and the crop material of these plants.

Preferably, compounds I and compositions thereof, respectively are used for controlling a multitude of fungi on field crops, such as potatoes sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rape, legumes, sunflowers, coffee or sugar cane; fruits; vines; ornamentals; or vegetables, such as cucumbers, tomatoes, beans or squashes.

The term “plant propagation material” is to be understood to denote all the generative parts of the plant such as seeds and vegetative plant material such as cuttings and tubers (e.g. potatoes), which can be used for the multiplication of the plant. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants, including seedlings and young plants, which are to be transplanted after germination or after emergence from soil.

These young plants may also be protected before transplantation by a total or partial treatment by immersion or pouring.

Preferably, treatment of plant propagation materials with compounds I and compositions thereof, respectively, is used for controlling a multitude of fungi on cereals, such as wheat, rye, barley and oats; rice, corn, cotton and soybeans.

The term “cultivated plants” is to be understood as including plants which have been modified by breeding, mutagenesis or genetic engineering including but not limiting to agricultural biotech products on the market or in development (cf. http://cera-gmc.org/, see GM crop database therein). Genetically modified plants are plants, which genetic material has been so modified by the use of recombinant DNA techniques that under natural circumstances cannot readily be obtained by cross breeding, mutations or natural recombination. Typically, one or more genes have been integrated into the genetic material of a genetically modified plant in order to improve certain properties of the plant. Such genetic modifications also include but are not limited to targeted post-translational modification of protein(s), oligo- or polypeptides e.g. by glycosylation or polymer additions such as prenylated, acetylated or farnesylated moieties or PEG moieties. Plants that have been modified by breeding, mutagenesis or genetic engineering, e.g. have been rendered tolerant to applications of specific classes of herbicides, such as auxin herbicides such as dicamba or 2,4-D; bleacher herbicides such as hydroxylphenylpyruvate dioxygenase (HPPD) inhibitors or phytoene desaturase (PDS) inhibitors; acetolactate synthase (ALS) inhibitors such as sulfonyl ureas or imidazolinones; enolpyruvylshikimate-3-phosphate synthase (EPSPS) inhibitors, such as glyphosate; glutamine synthetase (GS) inhibitors such as glufosinate; protoporphyrinogen-lX oxidase inhibitors; lipid biosynthesis inhibitors such as acetyl CoA carboxylase (ACCase) inhibitors; or oxynil (i.e. bromoxynil or ioxynil) herbicides as a result of conventional methods of breeding or genetic engineering. Furthermore, plants have been made resistant to multiple classes of herbicides through multiple genetic modifications, such as resistance to both glyphosate and glufosinate or to both glyphosate and a herbicide from another class such as ALS inhibitors, HPPD inhibitors, auxin herbicides, or ACCase inhibitors. These herbicide resistance technologies are e.g. described in Pest Managem. Sci. 61, 2005, 246; 61, 2005, 258; 61, 2005, 277; 61, 2005, 269; 61, 2005, 286; 64, 2008, 326; 64, 2008, 332; Weed Sci. 57, 2009, 108; Austral. J. Agricult. Res. 58, 2007, 708; Science 316, 2007, 1185; and references quoted therein. Several cultivated plants have been rendered tolerant to herbicides by conventional methods of breeding (mutagenesis), e.g. Clearfield® summer rape (Canola, BASF SE, Germany) being tolerant to imidazolinones, e.g. imazamox, or ExpressSun® sunflowers (DuPont, USA) being tolerant to sulfonyl ureas, e.g. tribenuron. Genetic engineering methods have been used to render cultivated plants such as soybean, cotton, corn, beets and rape, tolerant to herbicides such as glyphosate and glufosinate, some of which are commercially available under the trade names RoundupReady® (glyphosate-tolerant, Monsanto, U.S.A.), Cultivance® (imidazolinone tolerant, BASF SE, Germany) and LibertyLink® (glufosinate-tolerant, Bayer CropScience, Germany).

Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more insecticidal proteins, especially those known from the bacterial genus Bacillus, particularly from Bacillus thuringiensis, such as δ-endotoxins, e.g. CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c; vegetative insecticidal proteins (VIP), e.g. VIP1, VIP2, VIP3 or VIP3A; insecticidal proteins of bacteria colonizing nematodes, e.g. Photorhabdus spp. or Xenorhabdus spp.; toxins produced by animals, such as scorpion toxins, arachnid toxins, wasp toxins, or other insect-specific neurotoxins; toxins produced by fungi, such Streptomycetes toxins, plant lectins, such as pea or barley lectins; agglutinins; proteinase inhibitors, such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin or papain inhibitors; ribosome-inactivating proteins (RIP), such as ricin, maize-RIP, abrin, luffin, saporin or bryodin; steroid metabolism enzymes, such as 3-hydroxysteroid oxidase, ecdysteroid-IDP-glycosyl-transferase, cholesterol oxidases, ecdysone inhibitors or HMG-CoA-reductase; ion channel blockers, such as blockers of sodium or calcium channels; juvenile hormone esterase; diuretic hormone receptors (helicokinin receptors); stilbene synthase, bibenzyl synthase, chitinases or glucanases. In the context of the present invention these insecticidal proteins or toxins are to be understood expressly also as pre-toxins, hybrid proteins, truncated or otherwise modified proteins. Hybrid proteins are characterized by a new combination of protein domains, (see, e.g. WO 02/015701). Further examples of such toxins or genetically modified plants capable of synthesizing such toxins are disclosed, e.g., in EP-A 374 753, WO 93/007278, WO 95/34656, EP-A 427 529, EP-A 451 878, WO 03/18810 und WO 03/52073. The methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e.g. in the publications mentioned above. These insecticidal proteins contained in the genetically modified plants impart to the plants producing these proteins tolerance to harmful pests from all taxonomic groups of arthropods, especially to beetles (Coeloptera), two-winged insects (Diptera), and moths (Lepidoptera) and to nematodes (Nematoda). Genetically modified plants capable to synthesize one or more insecticidal proteins are, e.g., described in the publications mentioned above, and some of which are commercially available such as YieldGard® (corn cultivars producing the Cry1Ab toxin), YieldGard® Plus (corn cultivars producing Cry1Ab and Cry3Bb1 toxins), Starlink® (corn cultivars producing the Cry9c toxin), Herculex® RW (corn cultivars producing Cry34Ab1, Cry35Ab1 and the enzyme phosphinothricin-N-acetyltransferase [PAT]); NuCOTN® 33B (cotton cultivars producing the Cry1Ac toxin), Bollgard® I (cotton cultivars producing the Cry1Ac toxin), Bollgard® II (cotton cultivars producing Cry1Ac and Cry2Ab2 toxins); VIPCOT® (cotton cultivars producing a VIP-toxin); NewLeaf® (potato cultivars producing the Cry3A toxin); Bt-Xtra®, NatureGard®, KnockOut®, BiteGard®, Protecta®, Bt11 (e.g. Agrisure® CB) and Bt176 from Syngenta Seeds SAS, France, (corn cultivars producing the Cry1Ab toxin and PAT enyzme), MIR604 from Syngenta Seeds SAS, France (corn cultivars producing a modified version of the Cry3A toxin, c.f. WO 03/018810), MON 863 from Monsanto Europe S.A., Belgium (corn cultivars producing the Cry3Bb1 toxin), IPC 531 from Monsanto Europe S.A., Belgium (cotton cultivars producing a modified version of the Cry1Ac toxin) and 1507 from Pioneer Overseas Corporation, Belgium (corn cultivars producing the Cry1F toxin and PAT enzyme). Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the resistance or tolerance of those plants to bacterial, viral or fungal pathogens. Examples of such proteins are the so-called “pathogenesis-related proteins” (PR proteins, see, e.g. EP-A 392 225), plant disease resistance genes (e.g. potato cultivars, which express resistance genes acting against Phytophthora infestans derived from the Mexican wild potato Solanum bulbocastanum) or T4-lysozym (e.g. potato cultivars capable of synthesizing these proteins with increased resistance against bacteria such as Erwinia amylvora). The methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e.g. in the publications mentioned above.

Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the productivity (e.g. bio mass production, grain yield, starch content, oil content or protein content), tolerance to drought, salinity or other growth-limiting environmental factors or tolerance to pests and fungal, bacterial or viral pathogens of those plants.

Furthermore, plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve human or animal nutrition, e.g. oil crops that produce health-promoting long-chain omega-3 fatty acids or unsaturated omega-9 fatty acids (e.g. Nexera® rape, DOW Agro Sciences, Canada).

Furthermore, plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve raw material production, e.g. potatoes that produce increased amounts of amylopectin (e.g. Amflora® potato, BASF SE, Germany).

The compounds I and compositions thereof, respectively, are particularly suitable for controlling the following plant diseases:

Albugo spp. (white rust) on ornamentals, vegetables (e.g. A. candida) and sunflowers (e.g. A. tragopogonis); Alternaria spp. (Alternaria leaf spot) on vegetables, rape (A. brassicola or brassicae), sugar beets (A. tenuis), fruits, rice, soybeans, potatoes (e.g. A. solani or A. alternata), tomatoes (e.g. A. solani or A. alternata) and wheat; Aphanomyces spp. on sugar beets and vegetables; Ascochyta spp. on cereals and vegetables, e.g. A. tritici (anthracnose) on wheat and A. hordei on barley; Bipolaris and Drechslera spp. (teleomorph: Cochliobolus spp.), e.g. Southern leaf blight (D. maydis) or Northern leaf blight (B. zeicola) on corn, e.g. spot blotch (B. sorokiniana) on cereals and e.g. B. oryzae on rice and turfs; Blumeria (formerly Erysiphe) graminis (powdery mildew) on cereals (e.g. on wheat or barley); Botrytis cinerea (teleomorph: Botryotinia fuckeliana: grey mold) on fruits and berries (e.g. strawberries), vegetables (e.g. lettuce, carrots, celery and cabbages), rape, flowers, vines, forestry plants and wheat; Bremia lactucae (downy mildew) on lettuce; Ceratocystis (syn. Ophiostoma) spp. (rot or wilt) on broad-leaved trees and evergreens, e.g. C. ulmi (Dutch elm disease) on elms; Cercospora spp. (Cercospora leaf spots) on corn (e.g. Gray leaf spot: C. zeae-maydis), rice, sugar beets (e.g. C. beticola), sugar cane, vegetables, coffee, soybeans (e.g. C. sojina or C. kikuchii) and rice; Cladosporium spp. on tomatoes (e.g. C. fulvum: leaf mold) and cereals, e.g. C. herbarum (black ear) on wheat; Claviceps purpurea (ergot) on cereals; Cochliobolus (anamorph: Helminthosporium of Bipolaris) spp. (leaf spots) on corn (C. carbonum), cereals (e.g. C. sativus, anamorph: B. sorokiniana) and rice (e.g. C. miyabeanus, anamorph: H. oryzae); Colletotrichum (teleomorph: Glomerella) spp. (anthracnose) on cotton (e.g. C. gossypii), corn (e.g. C. graminicola: Anthracnose stalk rot), soft fruits, potatoes (e.g. C. coccodes: black dot), beans (e.g. C. lindemuthianum) and soybeans (e.g. C. truncatum or C. gloeosporioides); Corticium spp., e.g. C. sasakii (sheath blight) on rice; Corynespora cassiicola (leaf spots) on soybeans and ornamentals; Cycloconium spp., e.g. C. oleaginum on olive trees; Cylindrocarpon spp. (e.g. fruit tree canker or young vine decline, teleomorph: Nectria or Neonectria spp.) on fruit trees, vines (e.g. C. liriodendri, teleomorph: Neonectria liriodendri: Black Foot Disease) and ornamentals; Dematophora (teleomorph: Rosellinia) necatrix (root and stem rot) on soybeans; Diaporthe spp., e.g. D. phaseolorum (damping off) on soybeans; Drechslera (syn. Helminthosporium, teleomorph: Pyrenophora) spp. on corn, cereals, such as barley (e.g. D. teres, net blotch) and wheat (e.g. D. tritici-repentis: tan spot), rice and turf; Esca (dieback, apoplexy) on vines, caused by Formitiporia (syn. Phellinus) punctata, F. mediterranea, Phaeomoniella chlamydospora (earlier Phaeoacremonium chlamydosporum), Phaeoacremonium aleophillum and/or Botryosphaeria obtusa; Elsinoe spp. on pome fruits (E. pyri), soft fruits (E. veneta: anthracnose) and vines (E. ampelina: anthracnose); Entyloma oryzae (leaf smut) on rice; Epicoccum spp. (black mold) on wheat; Erysiphe spp. (powdery mildew) on sugar beets (E. betae), vegetables (e.g. E. pisi), such as cucurbits (e.g. E. cichoracearum), cabbages, rape (e.g. E. cruciferarum); Eutypa lata (Eutypa canker or dieback, anamorph: Cytosporina lata, syn. Libertella blepharis) on fruit trees, vines and ornamental woods; Exserohilum (syn. Helminthosporium) spp. on corn (e.g. E. turcicum); Fusarium (teleomorph: Gibberella) spp. (wilt, root or stem rot) on various plants, such as F. graminearum or F. culmorum (root rot, scab or head blight) on cereals (e.g. wheat or barley), F. oxysporum on tomatoes, F. solani (f. sp. glycines now syn. F. virguliforme) and F. tucumaniae and F. brasiliense each causing sudden death syndrome on soybeans, and F. verticillioides on corn; Gaeumannomyces graminis (take-all) on cereals (e.g. wheat or barley) and corn; Gibberella spp. on cereals (e.g. G. zeae) and rice (e.g. G. fujikuroi: Bakanae disease); Glomerella cingulata on vines, pome fruits and other plants and G. gossypii on cotton; Grainstaining complex on rice; Guignardia bidwellii (black rot) on vines; Gymnosporangium spp. on rosaceous plants and junipers, e.g. G. sabinae (rust) on pears; Helminthosporium spp. (syn. Drechslera, teleomorph: Cochliobolus) on corn, cereals and rice; Hemileia spp., e.g. H. vastatrix (coffee leaf rust) on coffee; Isariopsis clavispora (syn. Cladosporium vitis) on vines; Macrophomina phaseolina (syn. phaseoli) (root and stem rot) on soybeans and cotton; Microdochium (syn. Fusarium) nivale (pink snow mold) on cereals (e.g. wheat or barley); Microsphaera diffusa (powdery mildew) on soybeans; Monilinia spp., e.g. M. laxa, M. fructicola and M. fructigena (bloom and twig blight, brown rot) on stone fruits and other rosaceous plants; Mycosphaerella spp. on cereals, bananas, soft fruits and ground nuts, such as e.g. M. graminicola (anamorph: Septoria tritici Septoria blotch) on wheat or M. fijiensis (black Sigatoka disease) on bananas; Peronospora spp. (downy mildew) on cabbage (e.g. P. brassicae), rape (e.g. P. parasilica), onions (e.g. P. destructor), tobacco (P. tabacina) and soybeans (e.g. P. manshurica); Phakopsora pachyrhizi and P. meibomiae (soybean rust) on soybeans; Phialophora spp. e.g. on vines (e.g. P. tracheiphila and P. tetraspora) and soybeans (e.g. P. gregata: stem rot); Phoma lingam (root and stem rot) on rape and cabbage and P. betae (root rot, leaf spot and damping-off) on sugar beets; Phomopsis spp. on sunflowers, vines (e.g. P. viticola: can and leaf spot) and soybeans (e.g. stem rot: P. phaseoli, teleomorph: Diaporthe phaseolorum); Physoderma maydis (brown spots) on corn; Phytophthora spp. (wilt, root, leaf, fruit and stem root) on various plants, such as paprika and cucurbits (e.g. P. capsici), soybeans (e.g. P. megasperma, syn. P. sojae), potatoes and tomatoes (e.g. P. infestans, late blight) and broad-leaved trees (e.g. P. ramorum: sudden oak death); Plasmodiophora brassicae (club root) on cabbage, rape, radish and other plants; Plasmopara spp., e.g. P. viticola (grapevine downy mildew) on vines and P. halstedii on sunflowers; Podosphaera spp. (powdery mildew) on rosaceous plants, hop, pome and soft fruits, e.g. P. leucotricha on apples; Polymyxa spp., e.g. on cereals, such as barley and wheat (P. graminis) and sugar beets (P. betae) and thereby transmitted viral diseases; Pseudocercosporella herpotrichoides (eyespot, teleomorph: Tapesia yallundae) on cereals, e.g. wheat or barley; Pseudoperonospora (downy mildew) on various plants, e.g. P. cubensis on cucurbits or P. humili on hop; Pseudopezicula tracheiphila (red fire disease or ‘rotbrenner’, anamorph: Phialophora) on vines; Puccinia spp. (rusts) on various plants, e.g. P. triticina (brown or leaf rust), P. striiformis (stripe or yellow rust), P. hordei(dwarf rust), P. graminis (stem or black rust) or P. recondita (brown or leaf rust) on cereals, such as e.g. wheat, barley or rye, P. kuehnii(orange rust) on sugar cane and P. asparagi on asparagus; Pyrenophora (anamorph: Drechslera) tritici-repentis (tan spot) on wheat or P. teres (net blotch) on barley; Pyricularia spp., e.g. P. oryzae (teleomorph: Magnaporthe grisea, rice blast) on rice and P. grisea on turf and cereals; Pythium spp. (damping-off) on turf, rice, corn, wheat, cotton, rape, sunflowers, soybeans, sugar beets, vegetables and various other plants (e.g. P. ultimum or P. aphanidermatum); Ramularia spp., e.g. R. collo-cygni (Ramularia leaf spots, Physiological leaf spots) on barley and R. beticola on sugar beets; Rhizoctonia spp. on cotton, rice, potatoes, turf, corn, rape, potatoes, sugar beets, vegetables and various other plants, e.g. R. solani (root and stem rot) on soybeans, R. solani (sheath blight) on rice or R. cerealis (Rhizoctonia spring blight) on wheat or barley; Rhizopus stolonifer (black mold, soft rot) on strawberries, carrots, cabbage, vines and tomatoes; Rhynchosporium secalis (scald) on barley, rye and triticale; Sarocladium oryzae and S. attenuatum (sheath rot) on rice; Sclerotinia spp. (stem rot or white mold) on vegetables and field crops, such as rape, sunflowers (e.g. S. sclerotiorum) and soybeans (e.g. S. rolfsii or S. sclerotiorum); Septoria spp. on various plants, e.g. S. glycines (brown spot) on soybeans, S. tritici(Septoria blotch) on wheat and S. (syn. Stagonospora) nodorum (Stagonospora blotch) on cereals; Uncinula (syn. Erysiphe) necator (powdery mildew, anamorph: Oidium tuckeri) on vines; Setospaeria spp. (leaf blight) on corn (e.g. S. turcicum, syn. Helminthosporium turcicum) and turf; Sphacelotheca spp. (smut) on corn, (e.g. S. reiliana: head smut), sorghum und sugar cane; Sphaerotheca fuliginea (powdery mildew) on cucurbits; Spongospora subterranea (powdery scab) on potatoes and thereby transmitted viral diseases; Stagonospora spp. on cereals, e.g. S. nodorum (Stagonospora blotch, teleomorph: Leptosphaeria [syn. Phaeosphaeria] nodorum) on wheat; Synchytrium endobioticum on potatoes (potato wart disease); Taphrina spp., e.g. T. deformans (leaf curl disease) on peaches and T. pruni (plum pocket) on plums; Thielaviopsis spp. (black root rot) on tobacco, pome fruits, vegetables, soybeans and cotton, e.g. T. basicola (syn. Chalara elegans); Tilletia spp. (common bunt or stinking smut) on cereals, such as e.g. T. tritici (syn. T. caries, wheat bunt) and T. controversa (dwarf bunt) on wheat; Typhula incarnata (grey snow mold) on barley or wheat; Urocystis spp., e.g. U. occulta (stem smut) on rye; Uromyces spp. (rust) on vegetables, such as beans (e.g. U. appendiculatus, syn. U. phaseoli) and sugar beets (e.g. U. betae); Ustilago spp. (loose smut) on cereals (e.g. U. nuda and U. avaenae), corn (e.g. U. maydis: corn smut) and sugar cane; Venturia spp. (scab) on apples (e.g. V. inaequalis) and pears; and Verticllium spp. (wilt) on various plants, such as fruits and ornamentals, vines, soft fruits, vegetables and field crops, e.g. V. dahliae on strawberries, rape, potatoes and tomatoes. In a preferred embodiment the compounds I and compositions thereof, respectively, are particularly suitable for controlling the following plant diseases: Puccinia spp. (rusts) on various plants, for example, but not limited to P. triticina (brown or leaf rust), P. striiformis (stripe or yellow rust), P. hordei (dwarf rust), P. graminis (stem or black rust) or P. recondita (brown or leaf rust) on cereals, such as e.g. wheat, barley or rye and Phakopsoraceae spp. on various plants, in particular Phakopsora pachyrhizi and P. meibomiae (soybean rust) on soybeans.

The compounds I and compositions thereof, respectively, are also suitable for controlling harmful fungi in the protection of stored products or harvest and in the protection of materials. The term “protection of materials” is to be understood to denote the protection of technical and non-living materials, such as adhesives, glues, wood, paper and paperboard, textiles, leather, paint dispersions, plastics, cooling lubricants, fiber or fabrics, against the infestation and destruction by harmful microorganisms, such as fungi and bacteria. As to the protection of wood and other materials, the particular attention is paid to the following harmful fungi: Ascomycetes such as Ophiostoma spp., Ceratocystis spp., Aureobasidium pullulans, Scerophoma spp., Chaetomium spp., Humicola spp., Petriella spp., Trichurus spp.; Basidiomycetes such as Coniophora spp., Coriolus spp., Goeophyllum spp., Lentinus spp., Pleurotus spp., Poria spp., Serpula spp. and Tyromyces spp., Deuteromycetes such as Aspergillus spp., Cladosporium spp., Penicilllium spp., Trichoderma spp., Alternaria spp., Paecilomyces spp. and Zygomycetes such as Mucor spp., and in addition in the protection of stored products and harvest the following yeast fungi are worthy of note: Candida spp. and Saccharomyces cerevisae.

The method of treatment according to the invention can also be used in the field of protecting stored products or harvest against attack of fungi and microorganisms. According to the present invention, the term “stored products” is understood to denote natural substances of plant or animal origin and their processed forms, which have been taken from the natural life cycle and for which long-term protection is desired. Stored products of crop plant origin, such as plants or parts thereof, for example stalks, leafs, tubers, seeds, fruits or grains, can be protected in the freshly harvested state or in processed form, such as pre-dried, moistened, comminuted, ground, pressed or roasted, which process is also known as post-harvest treatment. Also falling under the definition of stored products is timber, whether in the form of crude timber, such as construction timber, electricity pylons and barriers, or in the form of finished articles, such as furniture or objects made from wood. Stored products of animal origin are hides, leather, furs, hairs and the like. The combinations according the present invention can prevent disadvantageous effects such as decay, discoloration or mold. Preferably “stored products” is understood to denote natural substances of plant origin and their processed forms, more preferably fruits and their processed forms, such as pomes, stone fruits, soft fruits and citrus fruits and their processed forms.

The compounds I and compositions thereof, respectively, may be used for improving the health of a plant. The invention also relates to a method for improving plant health by treating a plant, its propagation material and/or the locus where the plant is growing or is to grow with an effective amount of compounds I and compositions thereof, respectively.

The term “plant health” is to be understood to denote a condition of the plant and/or its products which is determined by several indicators alone or in combination with each other such as yield (e.g. increased biomass and/or increased content of valuable ingredients), plant vigor (e.g. improved plant growth and/or greener leaves (“greening effect”)), quality (e.g. improved content or composition of certain ingredients) and tolerance to abiotic and/or biotic stress. The above identified indicators for the health condition of a plant may be interdependent or may result from each other.

The compounds of formula I can be present in different crystal modifications whose biological activity may differ. They are likewise subject matter of the present invention.

The compounds I are employed as such or in form of compositions by treating the fungi or the plants, plant propagation materials, such as seeds, soil, surfaces, materials or rooms to be protected from fungal attack with a fungicidally effective amount of the active substances. The application can be carried out both before and after the infection of the plants, plant propagation materials, such as seeds, soil, surfaces, materials or rooms by the fungi.

Plant propagation materials may be treated with compounds I as such or a composition comprising at least one compound I prophylactically either at or before planting or transplanting.

The invention also relates to agrochemical compositions comprising an auxiliary and at least one compound I according to the invention.

An agrochemical composition comprises a fungicidally effective amount of a compound I. The term “effective amount” denotes an amount of the composition or of the compounds I, which is sufficient for controlling harmful fungi on cultivated plants or in the protection of materials and which does not result in a substantial damage to the treated plants. Such an amount can vary in a broad range and is dependent on various factors, such as the fungal species to be controlled, the treated cultivated plant or material, the climatic conditions and the specific compound I used.

The compounds I, their N-oxides and salts can be converted into customary types of agrochemical compositions, e.g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof. Examples for composition types are suspensions (e.g. SC, OD, FS), emulsifiable concentrates (e.g. EC), emulsions (e.g. EW, EO, ES, ME), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS, DP, DS), pressings (e.g. BR, TB, DT), granules (e.g. WG, SG, GR, FG, GG, MG), insecticidal articles (e.g. LN), as well as gel formulations for the treatment of plant propagation materials such as seeds (e.g. GF). These and further compositions types are defined in the “Catalogue of pesticide formulation types and international coding system”, Technical Monograph No. 2, 6^thEd. May 2008, CropLife International.

The compositions are prepared in a known manner, such as described by Mollet and Grubemann, Formulation technology, Wiley VCH, Weinheim, 2001; or Knowles, New developments in crop protection product formulation, Agrow Reports DS243, T&F Informa, London, 2005.

Suitable auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfactants, dispersants, emulsifiers, wetters, adjuvants, solubilizers, penetration enhancers, protective colloids, adhesion agents, thickeners, humectants, repellents, attractants, feeding stimulants, compatibilizers, bactericides, anti-freezing agents, anti-foaming agents, colorants, tackifiers and binders.

Suitable solvents and liquid carriers are water and organic solvents, such as mineral oil fractions of medium to high boiling point, e.g. kerosene, diesel oil; oils of vegetable or animal origin; aliphatic, cyclic and aromatic hydrocarbons, e.g. toluene, paraffin, tetrahydronaphthalene, alkylated naphthalenes; alcohols, e.g. ethanol, propanol, butanol, benzyl alcohol, cyclohexanol; glycols; DMSO; ketones, e.g. cyclohexanone; esters, e.g. lactates, carbonates, fatty acid esters, gamma-butyrolactone; fatty acids; phosphonates; amines; amides, e.g. N-methyl pyrrolidone, fatty acid dimethyl amides; and mixtures thereof. Suitable solid carriers or fillers are mineral earths, e.g. silicates, silica gels, talc, kaolins, limestone, lime, chalk, clays, dolomite, diatomaceous earth, bentonite, calcium sulfate, magnesium sulfate, magnesium oxide; polysaccharides, e.g. cellulose, starch; fertilizers, e.g. ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas; products of vegetable origin, e.g. cereal meal, tree bark meal, wood meal, nutshell meal, and mixtures thereof.

Suitable surfactants are surface-active compounds, such as anionic, cationic, nonionic and amphoteric surfactants, block polymers, polyelectrolytes, and mixtures thereof. Such surfactants can be used as emulsifier, dispersant, solubilizer, wetter, penetration enhancer, protective colloid, or adjuvant. Examples of surfactants are listed in McCutcheon's, Vol. 1: Emulsifiers & Detergents, McCutcheon's Directories, Glen Rock, USA, 2008 (International Ed. or North American Ed.).

Suitable anionic surfactants are alkali, alkaline earth or ammonium salts of sulfonates, sulfates, phosphates, carboxylates, and mixtures thereof. Examples of sulfonates are alkylaryl sulfonates, diphenyl sulfonates, alpha-olefin sulfonates, lignin sulfonates, sulfonates of fatty acids and oils, sulfonates of ethoxylated alkylphenols, sulfonates of alkoxylated arylphenols, sulfonates of condensed naphthalenes, sulfonates of dodecyl- and tridecylbenzenes, sulfonates of naphthalenes and alkyl naphthalenes, sulfosuccinates or sulfosuccinamates. Examples of sulfates are sulfates of fatty acids and oils, of ethoxylated alkylphenols, of alcohols, of ethoxylated alcohols, or of fatty acid esters. Examples of phosphates are phosphate esters. Examples of carboxylates are alkyl carboxylates, and carboxylated alcohol or alkylphenol ethoxylates.

Suitable nonionic surfactants are alkoxylates, N-substituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants, and mixtures thereof. Examples of alkoxylates are compounds such as alcohols, alkylphenols, amines, amides, arylphenols, fatty acids or fatty acid esters which have been alkoxylated with 1 to 50 equivalents. Ethylene oxide and/or propylene oxide may be employed for the alkoxylation, preferably ethylene oxide. Examples of N-substituted fatty acid amides are fatty acid glucamides or fatty acid alkanolamides. Examples of esters are fatty acid esters, glycerol esters or monoglycerides. Examples of sugar-based surfactants are sorbitans, ethoxylated sorbitans, sucrose and glucose esters or alkylpolyglucosides. Examples of polymeric surfactants are home- or copolymers of vinyl pyrrolidone, vinyl alcohols, or vinyl acetate.

Suitable cationic surfactants are quaternary surfactants, for example quaternary ammonium compounds with one or two hydrophobic groups, or salts of long-chain primary amines. Suitable amphoteric surfactants are alkylbetains and imidazolines. Suitable block polymers are block polymers of the A-B or A-B-A type comprising blocks of polyethylene oxide and polypropylene oxide, or of the A-B—C type comprising alkanol, polyethylene oxide and polypropylene oxide.

Suitable polyelectrolytes are polyacids or polybases. Examples of polyacids are alkali salts of polyacrylic acid or polyacid comb polymers. Examples of polybases are polyvinyl amines or polyethylene amines.

Suitable adjuvants are compounds, which have a negligible or even no pesticidal activity themselves, and which improve the biological performance of the compound I on the target. Examples are surfactants, mineral or vegetable oils, and other auxiliaries. Further examples are listed by Knowles, Adjuvants and additives, Agrow Reports DS256, T&F Informa UK, 2006, chapter 5.

Suitable thickeners are polysaccharides (e.g. xanthan gum, carboxymethyl cellulose), inorganic clays (organically modified or unmodified), polycarboxylates, and silicates.

Suitable bactericides are bronopol and isothiazolinone derivatives such as alkylisothiazolinones and benzisothiazolinones.

Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.

Suitable anti-foaming agents are silicones, long chain alcohols, and salts of fatty acids.

Suitable colorants (e.g. in red, blue, or green) are pigments of low water solubility and water-soluble dyes. Examples are inorganic colorants (e.g. iron oxide, titan oxide, iron hexacyanoferrate) and organic colorants (e.g. alizarin-, azo- and phthalocyanine colorants).

Suitable tackifiers or binders are polyvinyl pyrrolidones, polyvinyl acetates, polyvinyl alcohols, polyacrylates, biological or synthetic waxes, and cellulose ethers.

Examples for composition types and their preparation are:

i) Water-Soluble Concentrates (SL, LS)

10-60 wt % of a compound I and 5-15 wt % wetting agent (e.g. alcohol alkoxylates) are dissolved in water and/or in a water-soluble solvent (e.g. alcohols) ad 100 wt %. The active substance dissolves upon dilution with water.

ii) Dispersible Concentrates (DC)

5-25 wt % of a compound I and 1-10 wt % dispersant (e.g. polyvinyl pyrrolidone) are dissolved in organic solvent (e.g. cyclohexanone) ad 100 wt %. Dilution with water gives a dispersion.

iii) Emulsifiable Concentrates (EC)

15-70 wt % of a compound I and 5-10 wt % emulsifiers (e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate) are dissolved in water-insoluble organic solvent (e.g. aromatic hydrocarbon) ad 100 wt %. Dilution with water gives an emulsion.

iv) Emulsions (EW, EO, ES)

5-40 wt % of a compound I and 1-10 wt % emulsifiers (e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate) are dissolved in 20-40 wt % water-insoluble organic solvent (e.g. aromatic hydrocarbon). This mixture is introduced into water ad 100 wt % by means of an emulsifying machine and made into a homogeneous emulsion. Dilution with water gives an emulsion.

v) Suspensions (SC, OD, FS)

In an agitated ball mill, 20-60 wt % of a compound I are comminuted with addition of 2-10 wt % dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate), 0.1-2 wt % thickener (e.g. xanthan gum) and water ad 100 wt % to give a fine active substance suspension. Dilution with water gives a stable suspension of the active substance. For FS type composition up to 40 wt % binder (e.g. polyvinyl alcohol) is added.

vi) Water-Dispersible Granules and Water-Soluble Granules (WG, SG)

50-80 wt % of a compound I are ground finely with addition of dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate) ad 100 wt % and prepared as water-dispersible or water-soluble granules by means of technical appliances (e.g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substance.

vii) Water-Dispersible Powders and Water-Soluble Powders (WP, SP, WS)

50-80 wt % of a compound I are ground in a rotor-stator mill with addition of 1-5 wt % dispersants (e.g. sodium lignosulfonate), 1-3 wt % wetting agents (e.g. alcohol ethoxylate) and solid carrier (e.g. silica gel) ad 100 wt %. Dilution with water gives a stable dispersion or solution of the active substance.

viii) Gel (GW, GF)

In an agitated ball mill, 5-25 wt % of a compound I are comminuted with addition of 3-10 wt % dispersants (e.g. sodium lignosulfonate), 1-5 wt % thickener (e.g. carboxymethyl cellulose) and water ad 100 wt % to give a fine suspension of the active substance. Dilution with water gives a stable suspension of the active substance.

ix) Microemulsion (ME)

5-20 wt % of a compound I are added to 5-30 wt % organic solvent blend (e.g. fatty acid dimethyl amide and cyclohexanone), 10-25 wt % surfactant blend (e.g. alcohol ethoxylate and arylphenol ethoxylate), and water ad 100%. This mixture is stirred for 1 h to produce spontaneously a thermodynamically stable microemulsion.

x) Microcapsules (CS)

An oil phase comprising 5-50 wt % of a compound I, 0-40 wt % water insoluble organic solvent (e.g. aromatic hydrocarbon), 2-15 wt % acrylic monomers (e.g. methylmethacrylate, methacrylic acid and a di- or triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization results in the formation of poly(meth)acrylate microcapsules. Alternatively, an oil phase comprising 5-50 wt % of a compound I according to the invention, 0-40 wt % water insoluble organic solvent (e.g. aromatic hydrocarbon), and an isocyanate monomer (e.g. diphenylmethene-4,4′-diisocyanatae) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). The addition of a polyamine (e.g. hexamethylenediamine) results in the formation of polyurea microcapsules. The monomers amount to 1-10 wt %. The wt % relate to the total CS composition.

xi) Dustable Powders (DP, DS)

1-10 wt % of a compound I are ground finely and mixed intimately with solid carrier (e.g. finely divided kaolin) ad 100 wt %.

xii) Granules (GR, FG)

0.5-30 wt % of a compound I is ground finely and associated with solid carrier (e.g. silicate) ad 100 wt %. Granulation is achieved by extrusion, spray-drying or fluidized bed.

xiii) Ultra-Low Volume Liquids (UL)

1-50 wt % of a compound I are dissolved in organic solvent (e.g. aromatic hydrocarbon) ad 100 wt %.

The compositions types i) to xiii) may optionally comprise further auxiliaries, such as 0.1-1 wt % bactericides, 5-15 wt % anti-freezing agents, 0.1-1 wt % anti-foaming agents, and 0.1-1 wt % colorants.

The agrochemical compositions generally comprise between 0.01 and 95%, preferably between 0.1 and 90%, more preferably between 1 and 70%, and in particular between 10 and 60%, by weight of active substance. The active substances are employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).

For the purposes of treatment of plant propagation materials, particularly seeds, solutions for seed treatment (LS), Suspoemulsions (SE), flowable concentrates (FS), powders for dry treatment (DS), water-dispersible powders for slurry treatment (WS), water-soluble powders (SS), emulsions (ES), emulsifiable concentrates (EC), and gels (GF) are usually employed. The compositions in question give, after two-to-tenfold dilution, active substance concentrations of from 0.01 to 60% by weight, preferably from 0.1 to 40%, in the ready-to-use preparations. Application can be carried out before or during sowing. Methods for applying compound I and compositions thereof, respectively, onto plant propagation material, especially seeds, include dressing, coating, pelleting, dusting, and soaking as well as in-furrow application methods. Preferably, compound I or the compositions thereof, respectively, are applied on to the plant propagation material by a method such that germination is not induced, e.g. by seed dressing, pelleting, coating and dusting.

When employed in plant protection, the amounts of active substances applied are, depending on the kind of effect desired, from 0.001 to 2 kg per ha, preferably from 0.005 to 2 kg per ha, more preferably from 0.05 to 0.9 kg per ha, and in particular from 0.1 to 0.75 kg per ha.

In treatment of plant propagation materials such as seeds, e.g. by dusting, coating or drenching seed, amounts of active substance of from 0.1 to 1000 g, preferably from 1 to 1000 g, more preferably from 1 to 100 g and most preferably from 5 to 100 g, per 100 kilogram of plant propagation material (preferably seeds) are generally required.

When used in the protection of materials or stored products, the amount of active substance applied depends on the kind of application area and on the desired effect. Amounts customarily applied in the protection of materials are 0.001 g to 2 kg, preferably 0.005 g to 1 kg, of active substance per cubic meter of treated material.

Various types of oils, wetters, adjuvants, fertilizer, or micronutrients, and further pesticides (e.g. herbicides, insecticides, fungicides, growth regulators, safeners, biopesticides) may be added to the active substances or the compositions comprising them as premix or, if appropriate not until immediately prior to use (tank mix). These agents can be admixed with the compositions according to the invention in a weight ratio of 1:100 to 100:1, preferably 1:10 to 10:1.

A pesticide is generally a chemical or biological agent (such as pestidal active ingredient, compound, composition, virus, bacterium, antimicrobial or disinfectant) that through its effect deters, incapacitates, kills or otherwise discourages pests. Target pests can include insects, plant pathogens, weeds, mollusks, birds, mammals, fish, nematodes (roundworms), and microbes that destroy property, cause nuisance, spread disease or are vectors for disease. The term “pesticide” includes also plant growth regulators that alter the expected growth, flowering, or reproduction rate of plants; defoliants that cause leaves or other foliage to drop from a plant, usually to facilitate harvest; desiccants that promote drying of living tissues, such as unwanted plant tops; plant activators that activate plant physiology for defense of against certain pests; safeners that reduce unwanted herbicidal action of pesticides on crop plants; and plant growth promoters that affect plant physiology e.g. to increase plant growth, biomass, yield or any other quality parameter of the harvestable goods of a crop plant.

The user applies the composition according to the invention usually from a predosage device, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system. Usually, the agrochemical composition is made up with water, buffer, and/or further auxiliaries to the desired application concentration and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained. Usually, 20 to 2000 liters, preferably 50 to 400 liters, of the ready-to-use spray liquor are applied per hectare of agricultural useful area.

According to one embodiment, individual components of the composition according to the invention such as parts of a kit or parts of a binary or ternary mixture may be mixed by the user himself in a spray tank or any other kind of vessel used for applications (e.g. seed treater drums, seed pelleting machinery, knapsack sprayer) and further auxiliaries may be added, if appropriate.

Consequently, one embodiment of the invention is a kit for preparing a usable pesticidal composition, the kit comprising a) a composition comprising component 1) as defined herein and at least one auxiliary; and b) a composition comprising component 2) as defined herein and at least one auxiliary; and optionally c) a composition comprising at least one auxiliary and optionally a further active component 3) as defined herein.

Mixing the compounds I or the compositions comprising them in the use form as fungicides with other fungicides results in many cases in an expansion of the fungicidal spectrum of activity being obtained or in a prevention of fungicide resistance development. Furthermore, in many cases, synergistic effects are obtained.

The following list of pesticides II (e.g. pesticidally-active substances and biopesticides), in conjunction with which the compounds I can be used, is intended to illustrate the possible combinations but does not limit them:

A) Respiration inhibitors: Inhibitors of complex III at Q_osite: azoxystrobin (A.1.1), coumeth-oxystrobin (A.1.2), coumoxystrobin (A.1.3), dimoxystrobin (A.1.4), enestroburin (A.1.5), fenaminstrobin (A.1.6), fenoxystrobin/flufenoxystrobin (A.1.7), fluoxastrobin (A.1.8), kresoxim-methyl (A.1.9), mandestrobin (A.1.10), metominostrobin (A.1.11), orysastrobin (A.1.12), picoxy-strobin (A.1.13), pyraclostrobin (A.1.14), pyrametostrobin (A.1.15), pyraoxystrobin (A.1.16), trifloxystrobin (A.1.17), 2-(2-(3-(2,6-dichlorophenyl)-1-methyl-allylideneaminooxymethyl)-phenyl)-2-methoxyimino-N-methyl-acetamide (A.1.18), pyribencarb (A.1.19), triclopyricarb/chlorodincarb (A.1.20), famoxadone (A.1.21), fenamidone (A.1.21), methyl-N-[2-[(1,4-dimethyl-5-phenyl-pyrazol-3-yl)oxylmethyl]phenyl]-N-methoxy-carbamate (A.1.22), 1-[3-chloro-2-[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxymethyl]phenyl]-4-methyl-tetrazol-5-one (A.1.23), 1-[3-bromo-2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-4-methyl-tetra-5-one (A.1.24), 1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-methy-phenyl]-4-methyl-tetrazol-5-one (A.1.25), 1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-fluoro-phenyl]-4-methyl-tetrazol-5-one (A.1.26), 1-[2-[[1-(2,4-dichlorophenyl)pyrazol-3-yl]oxymethyl]-3-fluoro-phenyl]-4-methyl-tetrazol-5-one (A.1.27), 1-[2-[[4-(4-chlorophenyl)thiazol-2-yl]oxymethyl]-3-methyl-phenyl]4-methyl-tetrazol-5-one (A.1.28), 1-[3-chloro-2-[[4-(p-tolyl)thiazol-2-yl]oxymethyl]phenyl]-4-methyl-tetrazol-5-one (A.1.29), 1-[3-cyclopropropyl-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]-methyl]phenyl]-4-methyl-tetrazol-5-one (A.1.30), 1-[3-(difluoromethoxy)-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]methyl]phenyl]4-methyl-tetrazol-5-one (A.1.31), 1-methyl-4-[3-methyl-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]methyl]phenyl]tetrazol-5-one (A.1.32), 1-methyl-4-[3-methy-2-[[1-[3-(trifluormethyl)phenyl]-ethyldeneamino]oxymethyl]phenyl]tetrazol-5-one (A.1.33), (Z,2E)-5-[1-(2,4-dichlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide (A.1.34), (2E)-5-[1-(4-chlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide (A.1.35), pyriminostrobin (A.1.36), bifujunzhi (A.1.37), 2-(ortho-((2,5-dimethylphenyl-oxymethylene)phenyl)-3-methoxy-acrylic acid methylester (A.1.38).

Inhibitors of complex III at Q_isite: cyazofamid (A.2.1), amisulbrom (A.2.2), [(6S,7R,8R)-8-benzyl-3-[(3-hydroxy-4-methoxy-pyridine-2-carbonyl)amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylpropanoate (A.2.3), [2-[[(7R,8R,9S)-7-benzyl-9-methy-8-(2-methylpropanoyloxy)-2,6-dioxo-1,5-dioxonan-3-yl]carbamoyl]-4-methoxy-3-pyridyl]oxymethyl 2-methylpropanoate (A.2.4), [(6S,7R,8R)-8-benzyl-3-[[4-methoxy-3-(propanoyloxy-methoxy)pyridine-2-carbonyl]amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylpropanoate (A2.5).

Inhibitors of complex II: benodanil (A.3.1), benzovindiflupyr (A.3.2), bixafen (A.3.3), boscalid (A.3.4), carboxin (A.3.5), fenfuram (A.3.6), fluopyram (A.3.7), flutolanil (A.3.8), fluxapyroxad (A.3.9), furametpyr (A.3.10), isofetamid (A.3.11), isopyrazam (A.3.12), mepronil (A.3.13), oxycarboxin (A.3.14), penflufen (A.3.15), penthiopyrad (A.3.16), 3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazole-4-carboxamide (A.3.17), N-[2-(3,4-difluorophenyl)phenyl]-3-(trifluoromethyl)pyrazine-2-carboxamide (A.3.18), sedaxane (A.3.19), tecloftalam (A.3.20), thifluzamide (A.3.21), 3-(difluoromethyl)-1-methyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.22), 3-(trifluoromethyl)-1-methyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.23), 1,3-dimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.24), 3-(trifluoromethyl)-1,5-dimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.25), 1,3,5-trimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.26), 3-(difluoromethyl)-1,5-dimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.27), 3-(difluoromethyl)-N-(7-fluoro-1,1,3-trimethyl-indan-4-yl)-1-methyl-pyrazole-4-carboxamide (A.3.28), methyl (E)-2-[2-[(5-cyano-2-methyl-phenoxy)methyl]phenyl]-3-methoxy-prop-2-enoate (A.3.30), N-[(5-chloro-2-isopropyl-phenyl)methyl]-N-cyclopropyl-3-(difluoromethyl)-5 fluoro-1-methyl-pyrazole-4-carboxamide (A.3.31), 2-(difluoromethyl)-N-(1,1,3-trimethyl-indan-4-yl)pyridine-3-carboxamide (A.3.32), 2-(difluoromethyl)-N-[(3R)-1,1,3-trimethylindan-4-yl]pyridine-3-carboxamide (A.3.33), 2-(difluoromethyl)-N-(3-ethyl-1,1-dimethyl-indan-4-yl)¬pyridine-3-carboxamide (A.3.34), 2-(difluoromethyl)-N-[(3R)-3-ethyl-1,1-dimethyl-indan-4-yl]¬pyridine-3-carboxamide (A.3.35), 2-(difluoromethyl)-N-(1,1-dimethyl-3-propyl-indan-4-yl)¬py¬ridine-3-carboxamide (A.3.36), 2-(difluoromethyl)-N-[(3R)-1,1-dimethyl-3-propyl-indan-4-yl]¬pyridine-3-carboxamide (A.3.37), 2-(difluoromethyl)-N-(3-isobutyl-1,1-dimethyl-indan-4-yl)¬pyridine-3-carboxamide (A.3.38), 2-(difluoromethyl)-N-[(3R)-3-isobutyl-1,1-dimethyl-indan-4 yl]pyridine-3-carboxamide (A.3.39).

Other respiration inhibitors: diflumetorim (A.4.1); nitrophenyl derivates: binapacryl (A.4.2), dinobuton (A.4.3), dinocap (A.4.4), fluazinam (A.4.5), meptyldinocap (A.4.6), ferimzone (A.4.7); organometal compounds: fentin salts, e.g. fentin-acetate (A.4.8), fentin chloride (A.4.9) or fentin hydroxide (A.4.10); ametoctradin (A.4.11); silthiofam (A.4.12).

B) Sterol biosynthesis inhibitors (SBI fungicides)

C14 demethylase inhibitors: triazoles: azaconazole (B.1.1), bitertanol (B.1.2), bromuconazole (B.1.3), cyproconazole (B.1.4), difenoconazole (B.1.5), diniconazole (B.1.6), diniconazole-M (B.1.7), epoxiconazole (B.1.8), fenbuconazole (B.1.9), fluquinconazole (B.1.10), flusilazole (B.1.11), flutriafol (B.1.12), hexaconazole (B.1.13), imibenconazole (B.1.14), ipconazole (B.1.15), metconazole (B.1.17), myclobutanil (B.1.18), oxpoconazole (B.1.19), paclobutrazole (B.1.20), penconazole (B.1.21), propiconazole (B.1.22), prothioconazole (B.1.23), simeconazole (B.1.24), tebuconazole (B.1.25), tetraconazole (B.1.26), triadimefon (B.1.27), triadimenol (B.1.28), triticonazole (B.1.29), uniconazole (B.1.30), 1-[reb(2S3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)-oxiranylmethyl]-5-thiocyanato-1H-[1,2,4]triazole (B.1.31), 2-[reb(2S;3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)-oxiranylmethyl]-2H-[1,2,4]triazole-3-thiol (B.1.32), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)pentan-2-ol (B.1.33), 1-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-cyclopropyl-2-(1,2,4-triazol-1-yl)ethanol (B.1.34), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)butan-2-ol (B.1.35), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)butan-2-ol (B.1.36), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-3-methyl-1-(1,2,4-triazol-1-yl)butan-2-ol (B.1.37), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (B.1.38), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-3-methyl-1-(1,2,4-triazol-1-yl)butan-2-ol (B.1.39), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)pentan-2-ol (B.1.40), 2-[4-(4-fluorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (B.1.41), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)pent-3-yn-2-ol (B.1.42), 2-(chloromethyl)-2-methyl-5-(p-tolylmethyl)-1-(1,2,4-triazol-1-ylmethyl)cyclopentanol (B.1.43); imidazoles: imazalil (B.1.44), pefurazoate (B.1.45), prochloraz (B.1.46), triflumizol (B.1.47); pyrimidines, pyridines and piperazines: fenarimol (B.1.49), pyrifenox (B.1.50), triforine (B.1.51), [3-(4-chloro-2-fluoro-phenyl)-5-(2,4-difluorophenyl)isoxazol-4-yl]-(3-pyridyl)methanol (B.1.52).

Delta14-reductase inhibitors: aldimorph (B.2.1), dodemorph (B.2.2), dodemorph-acetate (B.2.3), fenpropimorph (B.2.4), tridemorph (B.2.5), fenpropidin (B.2.6), piperalin (B.2.7), spiroxamine (B.2.8).

Inhibitors of 3-keto reductase: fenhexamid (B.3.1).

Other Sterol biosynthesis inhibitors: chlorphenomizole (B.4.1).

C) Nucleic Acid Synthesis Inhibitors

Phenylamides or acyl amino acid fungicides: benalaxyl (C.1.1), benalaxyl-M (C.1.2), kiralaxyl (C.1.3), metalaxyl (C.1.4), metalaxyl-M (C.1.5), ofurace (C.1.6), oxadixyl (C.1.7).

Other nucleic acid synthesis inhibitors: hymexazole (C.2.1), octhilinone (C.2.2), oxolinic acid (C.2.3), bupirimate (C.2.4), 5-fluorocytosine (C.2.5), 5-fluoro-2-(p-tolylmethoxy)pyrimidin-4-amine (C.2.6), 5-fluoro-2-(4-fluorophenylmethoxy)pyrimidin-4-amine (C.2.7), 5-fluoro-2-(4-chlorophenylmethoxy)pyrimidin-4 amine (C.2.8).

D) Inhibitors of Cell Division and Cytoskeleton

Tubulin inhibitors: benomyl (D.1.1), carbendazim (D.1.2), fuberidazole (D1.3), thiabendazole (D.1.4), thiophanate-methyl (D.1.5), 3-chloro-4-(2,6-difluorophenyl)-6-methyl-5-phenyl-pyridazine (D.1.6), 3-chloro-6-methyl-5-phenyl-4-(2,4,6-trifluorophenyl)pyridazine (D.1.7), N-ethyl-2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]butanamide (D.1.8), N-ethyl-2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methylsulfanyl-acetamide (D.1.9), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-(2-fluoroethyl)butanamide (D.1.10), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-(2-fluoroethyl)-2-methoxy-acetamide (D.1.11), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-propyl-butanamide (D.1.12), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methoxy-N-propyl-acetamide (D.1.13), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methylsulfanyl-N-propyl-acetamide (D.1.14), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-(2-fluoroethyl)-2-methylsulfanyl-acetamide (D.1.15), 4-(2-bromo-4-fluoro-phenyl)-N-(2-chloro-6-fluoro-phenyl)-2,5-dimethyl-pyrazol-3-amine (D.1.16).

Other cell division inhibitors: diethofencarb (D.2.1), ethaboxam (D.2.2), pencycuron (D.2.3), fluopicolide (D.2.4), zoxamide (D.2.5), metrafenone (D.2.6), pyriofenone (D.2.7).

E) Inhibitors of Amino Acid and Protein Synthesis

Methionine synthesis inhibitors: cyprodinil (E.1.1), mepanipyrim (E.1.2), pyrimethanil (E.1.3). Protein synthesis inhibitors: blasticidin-S(E.2.1), kasugamycin (E.2.2), kasugamycin hydrochloride-hydrate (E.2.3), mildiomycin (E.2.4), streptomycin (E.2.5), oxytetracyclin (E.2.6).

F) Signal Transduction Inhibitors

MAP/histidine kinase inhibitors: fluoroimid (F.1.1), iprodione (F.1.2), procymidone (F.1.3), vinclozolin (F.1.4), fludioxonil (F.1.5).

G protein inhibitors: quinoxyfen (F.2.1).

G) Lipid and Membrane Synthesis Inhibitors

Phospholipid biosynthesis inhibitors: edifenphos (G.1.1), iprobenfos (G.1.2), pyrazophos (G.1.3), isoprothiolane (G.1.4).

Lipid peroxidation: dicloran (G.2.1), quintozene (G.2.2), tecnazene (G.2.3), tolclofos-methyl (G.2.4), biphenyl (G.2.5), chloroneb (G.2.6), etridiazole (G.2.7).

Phospholipid biosynthesis and cell wall deposition: dimethomorph (G.3.1), flumorph (G.3.2), mandipropamid (G.3.3), pyrimorph (G.3.4), benthiavalicarb (G.3.5), iprovalicarb (G.3.6), valifenalate (G.3.7).

Compounds affecting cell membrane permeability and fatty acids: propamocarb (G.4.1). Inhibitors of oxysterol binding protein: oxathiapiprolin (G.5.1), 2-{3-[2-(1-{[3,5-bis(difluoromethyl-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}phenyl methanesulfonate (G.5.2), 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl) 1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate (G.5.3), 4-[1-[2-[3-(difluoromethyl)-5-methyl-pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.4), 4-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.5), 4-[1-[2-[3-(difluoromethyl)-5-(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.6), 4-[1-[2-[5-cyclopropyl-3-(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.7), 4-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.8), 4-[1-[2-[5-(difluoromethyl)-3-(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.9), 4-[1-[2-[3,5-bis(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.10), (4-[1-[2-[5-cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.11).

H) Inhibitors with Multi Site Action

Inorganic active substances: Bordeaux mixture (H.1.1), copper (H.1.2), copper acetate (H.1.3), copper hydroxide (H.1.4), copper oxychloride (H.1.5), basic copper sulfate (H.1.6), sulfur (H.1.7).

Thio- and dithiocarbamates: ferbam (H.2.1), mancozeb (H.2.2), maneb (H.2.3), metam (H.2.4), metiram (H.2.5), propineb (H.2.6), thiram (H.2.7), zineb (H.2.8), ziram (H.2.9).

Organochlorine compounds: anilazine (H.3.1), chlorothalonil (H.3.2), captafol (H.3.3), captan (H.3.4), folpet (H.3.5), dichlofluanid (H.3.6), dichlorophen (H.3.7), hexachlorobenzene (H.3.8), pentachlorphenole (H.3.9) and its salts, phthalide (H.3.10), tolylfluanid (H.3.11).

Guanidines and others: guanidine (H.4.1), dodine (H.4.2), dodine free base (H.4.3), guazatine (H.4.4), guazatine-acetate (H.4.5), iminoctadine (H.4.6), iminoctadine-triacetate (H.4.7), iminoctadine-tris(albesilate) (H.4.8), dithianon (H.4.9), 2,6-dimethyl-1H,5H-[1,4]dithiino[2,3-c:5,6-c′]dipyrrole-1,3,5,7(2H,6H)-tetraone (H.4.10).

I) Cell Wall Synthesis Inhibitors

Inhibitors of glucan synthesis: validamycin (I.1.1), polyoxin B (I.1.2).

Melanin synthesis inhibitors: pyroquilon (I.2.1), tricyclazole (I.2.2), carpropamid (I.2.3), dicyclomet (I.2.4), fenoxanil (I.2.5).

J) Plant Defence Inducers

Acibenzolar-S-methyl (J.1.1), probenazole (J.1.2), isotianil (J.1.3), tiadinil (J.1.4), prohexadione-calcium (J.1.5); phosphonates: fosetyl (J.1.6), fosetyl-aluminum (J.1.7), phosphorous acid and its salts (J.1.8), potassium or sodium bicarbonate (J.1.9), 4-cyclopropyl-N-(2,4-dimethoxyphenyl)thiadiazole-5-carboxamide (J.1.10).

K) Unknown Mode of Action

Bronopol (K.1.1), chinomethionat (K.1.2), cyflufenamid (K.1.3), cymoxanil (K.1.4), dazomet (K.1.5), debacarb (K.1.6), diclocymet (K.1.7), diclomezine (K.1.8), difenzoquat (K.1.9), di-fenzoquat-methylsulfate (K.1.10), diphenylamin (K.1.11), fenitropan (K.1.12), fenpyrazamine (K.1.13), flumetover (K.1.14), flusulfamide (K.1.15), flutianil (K.1.16), harpin (K.1.17), metha-sulfocarb (K.1.18), nitrapyrin (K.1.19), nitrothal-isopropyl (K.1.20), tolprocarb (K.1.21), oxin-copper (K.1.22), proquinazid (K.1.23), tebufloquin (K.1.24), tecloftalam (K.1.25), triazoxide (K.1.26), N′-(4-(4-chloro-3-trifluoromethyl-phenoxy)-2,5-dimethyl-phenyl)-N-ethyl-N-methyl formamidine (K.1.27), N′-(4-(4-fluoro-3-trifluoromethyl-phenoxy)-2,5-dimethyl-phenyl)-N-ethyl-N-methyl formamidine (K.1.28), N′-[4-[[3-[(4-chlorophenyl)methyl]-1,2,4-thiadiazol-5-yl]oxy]-2,5-dimethyl-phenyl]-N-ethyl-N-methyl-formamidine (K.1.29), N′-(5-bromo-6-indan-2-yloxy-2-methyl-3-pyridyl)-N-ethyl-N-methyl-formamidine (K.1.30), N′-[5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methyl-3-pyridyl]-N-ethyl-N-methyl-formamidine (K.1.31), N′-[5-bromo-6-(4-isopropylcyclohexoxy)-2-methyl-3-pyridyl]-N-ethyl-N-methyl-formamidine (K.1.32), N′-[5-bromo-2-methyl-6-(1-phenylethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine (K.1.33), N′-(2-methyl-5-trifluoromethyl-4-(3-trimethylsilanyl-propoxy)-phenyl)-N-ethyl-N-methyl formamidine (K.1.34), N′-(5-difluoromethyl-2-methyl-4-(3-trimethylsilanyl-propoxy)-phenyl)-N-ethyl-N-methyl formamidine (K.1.35), 2-(4-chloro-phenyl)-N-[4-(3,4-dimethoxy-phenyl)-isoxazol-5-yl]-2-prop-2-ynyloxy-acetamide (K.1.36), 3-[5-(4-chloro-phenyl)-2,3-dimethyl-isoxazolidin-3-yl]-pyridine (pyrisoxazole) (K.1.37), 3-[5-(4-methylphenyl)-2,3-dimethyl-isoxazolidin-3 yl]-pyridine (K.1.38), 5-chloro-1-(4,6-dimethoxy-pyrimidin-2-yl)-2-methyl-1H-benzoimidazole (K.1.39), ethyl (Z)-3-amino-2-cyano-3-phenyl-prop-2-enoate (K.1.40), picarbutrazox (K.1.41), pentyl N-[6-[[(Z)-[(1-methyltetrazol-5-yl)-phenyl-methylene]amino]oxymethyl]-2-pyridyl]carbamate (K.1.42), but-3-ynyl N-[6-[[(Z)-[(1-methyltetrazol-5-yl)-phenyl-methylene]amino]oxymethyl]-2-pyridyl]carbamate (K.1.43), 2-[2-[(7,8-difluoro-2-methyl-3-quinolyl)oxy]-6-fluoro-phenyl]propan-2-ol (K.1.44), 2-[2-fluoro-6-[(8-fluoro-2-methyl-3-quinolyl)oxy]phen-yl]propan-2-ol (K.1.45), 3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinolin-1-yl)quinoline (K.1.46), quinofumelin (K.1.47), 3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline (K.1.48), 9-fluoro-2,2-dimethyl-5-(3-quinolyl)-3H-1,4-benzoxazepine (K.1.49), 2-(6-benzyl-2-pyridyl)quinazoline (K.1.50), 2-[6-(3-fluoro-4-methoxy-phenyl)-5-methyl-2-pyridyl]quinazoline (K.1.51), 3-[(3,4-dichloroisothiazol-5-yl)methoxy]-1,2-benzothiazole 1,1-dioxide (K.1.52), N′-(2,5-dimethyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine (K.1.53).

M) Growth Regulators

abscisic acid (M.1.1), amidochlor, ancymidol, 6-benzylaminopurine, brassinolide, butralin, chlormequat, chlormequat chloride, choline chloride, cyclanilide, daminozide, dikegulac, dimethipin, 2,6-dimethylpuridine, ethephon, flumetralin, flurprimidol, fluthiacet, forchlorfenuron, gibberellic acid, inabenfide, indole-3-acetic acid, maleic hydrazide, mefluidide, mepiquat, mepiquat chloride, naphthaleneacetic acid, N-6-benzyladenine, paclobutrazol, prohexadione, prohexadione-calcium, prohydrojasmon, thidiazuron, triapenthenol, tributyl phosphorotrithioate, 2,3,5-tri-iodobenzoic acid, trinexapac-ethyl and uniconazole;

N) Herbicides from Classes N.1 to N.15

N.1 Lipid biosynthesis inhibitors: alloxydim (N.1.1), alloxydim-sodium (N.1.2), butroxydim (N.1.3), clethodim (N.1.4), clodinafop (N.1.5), clodinafop-propargyl (N.1.6), cycloxydim (N.1.7), cyhalofop (N.1.8), cyhalofop-butyl (N.1.9), diclofop(N.1.10), diclofop-methyl (N.1.11), fenoxaprop (N.1.12), fenoxaprop-ethyl (N.1.13), fenoxaprop-P (N.1.14), fenoxaprop-P-ethyl (N.1.15), fluazifop (N.1.16), fluazifop-butyl (N.1.17), fluazifop-P (N.1.18), fluazifop-P-butyl (N.1.19), haloxyfop (N.1.20), haloxyfop-methyl (N.1.21), haloxyfop-P (N.1.22), haloxyfop-P-methyl (N.1.23), metamifop (N.1.24), pinoxaden (N.1.25), profoxydim (N.1.26), propaquizafop (N.1.27), quizalofop (N.1.28), quizalofop-ethyl (N.1.29), quizalofop-tefuryl (N.1.30), quizalofop-P (N.1.31), quizalofop-P-ethyl (N.1.32), quizalofop-P-tefuryl (N.1.33), sethoxydim (N.1.34), tepraloxydim (N.1.35), tralkoxydim (N.1.36), 4-(4′-chloro-4-cyclo-propyl-2′-fluoro[1,1′-biphenyl]-3-yl)-5-hydroxy-2,2,6,6-tetramethyl-2H-pyran-3(6H)-one ((N.1.37) CAS 1312337-72-6); 4-(2′,4′-dichloro-4-cyclopropyl[1,1′-biphenyl]-3-yl)-5-hydroxy-2,2,6,6-tetramethyl-2H-pyran-3(6H)-one ((N.1.38) CAS 1312337-45-3); 4-(4′-chloro-4-ethyl-2′-fluoro[1,1′-biphenyl]-3-yl)-5-hydroxy-2,2,6,6-tetramethyl-2H-pyran-3(6H)-one ((N.1.39) CAS 1033757-93-5); 4-(2′,4′-Dichloro-4-ethyl[1,1′-biphenyl]-3-yl)-2,2,6,6-tetramethyl-2H-pyran-3,5(4H,6H)-dione ((N.1.40) CAS 1312340-84-3); 5-(acetyloxy)-4-(4′-chloro-4-cyclopropyl-2′-fluoro[1,1′-biphenyl]-3-yl)-3,6-dihydro-2,2,6,6-tetramethyl-2H-pyran-3-one ((N.1.41) CAS 1312337-48-6); 5-(acetyloxy)-4-(2′,4′-dichloro-4-cyclopropyl-[1,1′-biphenyl]-3-yl)-3,6-dihydro-2,2,6,6-tetramethyl-2H-pyran-3-one (N.1.42); 5-(acetyloxy)-4-(4′-chloro-4-ethyl-2′-fluoro[1,1′-biphenyl]-3-yl)-3,6-dihydro-2,2,6,6-tetramethyl-2H-pyran-3-one ((N.1.43) CAS 1312340-82-1); 5-(acetyloxy)-4-(2′,4′-dichloro-4-ethyl[1,1′-biphenyl]-3-yl)-3,6-dihydro-2,2,6,6-tetramethyl-2H-pyran-3-one ((N.1.44) CAS 1033760-55-2); 4-(4′-chloro-4-cyclopropyl-2′-fluoro[1,1′-biphenyl]-3-yl)-5,6-dihydro-2,2,6,6-tetramethyl-5-oxo-2H-pyran-3-yl carbonic acid methyl ester ((N.1.45) CAS 1312337-51-1); 4-(2′,4′-dichloro-4-cyclopropyl-[1,1′-biphenyl]-3-yl)-5,6-dihydro-2,2,6,6-tetramethyl-5-oxo-2H-pyran-3-yl carbonic acid methyl ester (N.1.46); 4-(4′-chloro-4-ethyl-2′-fluoro[1,1′-biphenyl]-3-yl)-5,6-dihydro-2,2,6,6-tetramethyl-5-oxo-2H-pyran-3-yl carbonic acid methyl ester ((N.1.47) CAS 1312340-83-2); 4-(2′,4′-dichloro-4-ethylh[1,1′-biphenyl]-3-yl)-5,6-dihydro-2,2,6,6-tetramethyl-5-oxo-2H-pyran-3-yl carbonic acid methyl ester ((N.1.48) CAS 1033760-58-5); benfuresate (N.1.49), butylate (N.1.50), cycloate (N.1.51), dalapon (N.1.52), dimepiperate (N.1.53), EPTC (N.1.54), esprocarb (N.1.55), ethofumesate (N.1.56), flupropanate (N.1.57), molinate (N.1.58), orbencarb (N.1.59), pebulate (N.1.60), prosulfocarb (N.1.61), TCA (N.1.62), thiobencarb (N.1.63), tiocarbazil (N.1.64), triallate (N.1.65) and vernolate (N.1.66);

N.2 ALS inhibitors: amidosulfuron (N.2.1), azimsulfuron (N.2.2), bensulfuron (N.2.3), bensul-furon-methyl (N.2.4), chlorimuron (N.2.5), chlorimuron-ethyl (N.2.6), chlorsulfuron (N.2.7), cinosulfuron (N.2.8), cyclosulfamuron (N.2.9), ethametsulfuron (N.2.10), ethametsulfuron-methyl (N.2.11), ethoxysulfuron (N.2.12), flazasulfuron (N.2.13), flucetosulfuron (N.2.14), flupyrsulfuron (N.2.15), flupyrsulfuron-methyl-sodium (N.2.16), foramsulfuron (N.2.17), halosulfuron (N.2.18), halosulfuron-methyl (N.2.19), imazosulfuron (N.2.20), iodosulfuron (N.2.21), iodosulfuron-methyl-sodium (N.2.22), iofensulfuron (N.2.23), iofensulfuron-sodium (N.2.24), mesosulfuron (N.2.25), metazosulfuron (N.2.26), metsulfuron (N.2.27), metsulfuron-methyl (N.2.28), nicosulfuron (N.2.29), orthosulfamuron (N.2.30), oxasulfuron (N.2.31), primisulfuron (N.2.32), primisulfuron-methyl (N.2.33), propyrisulfuron (N.2.34), prosulfuron (N.2.35), pyrazosulfuron (N.2.36), pyrazosulfuron-ethyl (N.2.37), rimsulfuron (N.2.38), sulfometuron (N.2.39), sulfometuron-methyl (N.2.40), sulfosulfuron (N.2.41), thifensulfuron (N.2.42), thifensulfuron-methyl (N.2.43), triasulfuron (N.2.44), tribenuron (N.2.45), tribenuron-methyl (N.2.46), trifloxysulfuron (N.2.47), triflusulfuron (N.2.48), triflusulfuron-methyl (N.2.49), tritosulfuron (N.2.50), imazamethabenz (N.2.51), imazamethabenz-methyl (N.2.52), imazamox (N.2.53), imazapic (N.2.54), imazapyr (N.2.55), imazaquin (N.2.56), imazethapyr (N.2.57); cloransulam (N.2.58), cloransulam-methyl (N.2.59), diclosulam (N.2.60), flumetsulam (N.2.61), florasulam (N.2.62), metosulam (N.2.63), penoxsulam (N.2.64), pyrimisulfan (N.2.65) and pyroxsulam (N.2.66); bispyribac (N.2.67), bispyribac-sodium (N.2.68), pyribenzoxim (N.2.69), pyriftalid (N.2.70), pyriminobac (N.2.71), pyriminobac-methyl (N.2.72), pyrithiobac (N.2.73), pyrithiobac-sodium (N.2.74), 4-[[[2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]phenyl]methyl]amino]-benzoic acid-1-methyl-ethyl ester ((N.2.75) CAS 420138-41-6), 4-[[[2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]phenyl]-methyl]amino]-benzoic acid propyl ester ((N.2.76) CAS 420138-40-5), N-(4-bromophenyl)-2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]benzenemethanamine ((N.2.77) CAS 420138-01-8); flucarbazone (N.2.78), flucarbazone-sodium (N.2.79), propoxycarbazone (N.2.80), propoxycarbazone-sodium (N.2.81), thiencarbazone (N.2.82), thiencarbazone-methyl (N.2.83), triafamone (N.2.84);

N.3 Photosynthesis inhibitors: amicarbazone (N.3.1); chlorotriazine (N.3.2); ametryn (N.3.3), atrazine (N.3.4), chloridazone (N.3.5), cyanazine (N.3.6), desmetryn (N.3.7), dimethametryn (N.3.8), hexazinone (N.3.9), metribuzin (N.3.10), prometon (N.3.11), prometryn (N.3.12), pro-pazine (N.3.13), simazine (N.3.14), simetryn (N.3.15), terbumeton (N.3.16), terbuthylazin (N.3.17), terbutryn (N.3.18), trietazin (N.3.19); chlorobromuron (N.3.20), chlorotoluron (N.3.21), chloroxuron (N.3.22), dimefuron (N.3.23), diuron (N.3.24), fluometuron (N.3.25), isoproturon (N.3.26), isouron (N.3.27), linuron (N.3.28), metamitron (N.3.29), methabenzthiazuron (N.3.30), metobenzuron (N.3.31), metoxuron (N.3.32), monolinuron (N.3.33), neburon (N.3.34), siduron (N.3.35), tebuthiuron (N.3.36), thiadiazuron (N.3.37), desmedipham (N.3.38), karbutilat (N.3.39), phenmedipham (N.3.40), phenmedipham-ethyl (N.3.41), bromofenoxim (N.3.42), bromoxynil (N.3.43) and its salts and esters, ioxynil (N.3.44) and its salts and esters, bromacil (N.3.45), lenacil (N.3.46), terbacil (N.3.47), bentazon (N.3.48), bentazon-sodium (N.3.49), pyridate (N.3.50), pyridafol (N.3.51), pentanochlor (N.3.52), propanil (N.3.53); diquat (N.3.54), diquat-dibromide (N.3.55), paraquat (N.3.56), paraquat-dichloride (N.3.57), paraquat-dimetilsulfate (N.3.58);

N.4 protoporphyrinogen-IX oxidase inhibitors: acifluorfen (N.4.1), acifluorfen-sodium (N.4.2), azafenidin (N.4.3), bencarbazone (N.4.4), benzfendizone (N.4.5), bifenox (N.4.6), butafenacil (N.4.7), carfentrazone (N.4.8), carfentrazone-ethyl (N.4.9), chlormethoxyfen (N.4.10), cinidon-ethyl (N.4.11), fluazolate (N.4.12), flufenpyr (N.4.13), flufenpyr-ethyl (N.4.14), flumiclorac (N.4.15), flumiclorac-pentyl (N.4.16), flumioxazin (N.4.17), fluoroglycofen (N.4.18), fluoroglycofen-ethyl (N.4.19), fluthiacet (N.4.20), fluthiacet-methyl (N.4.21), fomesafen (N.4.22), halosafen (N.4.23), lactofen (N.4.24), oxadiargyl (N.4.25), oxadiazon (N.4.26), oxyfluorfen (N.4.27), pentoxazone (N.4.28), profluazol (N.4.29), pyraclonil (N.4.30), pyraflufen (N.4.31), pyraflufen-ethyl (N.4.32), saflufenacil (N.4.33), sulfentrazone (N.4.34), thidiazimin (N.4.35), tiafenacil (N.4.36), trifludimoxazin (N.4.37), ethyl [3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)phenoxy]-2-pyridyloxy]acetate ((N.4.38) CAS 353292-31-6), N-ethyl-3-(2,6-dichloro-4-trifluoro-methylphenoxy)-5-methyl-1H-pyrazole-1-carboxamide ((N.4.39) CAS 452098-92-9), N tetrahydrofurfuryl-3-(2,6-dichloro-4-trifluoromethylphenoxy)-5-methyl-1H-pyrazole-1-carboxamide ((N.4.40) CAS 915396-43-9), N-ethyl-3-(2-chloro-6-fluoro-4-trifluoromethylhphenoxy)-5-methyl-1H-pyrazole-1-carboxamide ((N.4.41) CAS 452099-05-7), N tetrahydro-furfuryl-3-(2-chloro-6-fluoro-4-trifluoro-methylphenoxy)-5-methyl-1H-pyrazole-1-carboxamide ((N.4.42) CAS 452100-03-7), 3-[7-fluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl]-1,5-dimethyl-6-thioxo-[1,3,5]triazinan-2,4-dione ((N.4.43) CAS 451484-50-7), 2-(2,2,7-trifluoro-3-oxo-4-prop-2-ynyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-4,5,6,7-tetrahydro-isoindole-1,3-dione ((N.4.44) CAS 1300118-96-0), 1-methyl-6-trifluoro-methyl-3-(2,2,7-tri-fluoro-3-oxo-4-prop-2-ynyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-1H-pyrimidine-2,4-dione ((N.4.45) CAS 1304113-05-0), methyl (E)-4-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1H-methyl-pyrazol-3-yl]-4-fluoro-phenoxy]-3-methoxy-but-2-enoate ((N.4.46) CAS 948893-00-3), 3-[7-chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazol-4-yl]-1-methyl-6-(trifluoromethyl)-1H-pyrimidine-2,4-dione ((N.4.47) CAS 212754-02-4);

N.5 Bleacher herbicides: beflubutamid (N.5.1), diflufenican (N.5.2), fluridone (N.5.3), flurochloridone (N.5.4), flurtamone (N.5.5), norflurazon (N.5.6), picolinafen (N.5.7), 4-(3-trifluoromethylhphenoxy)-2-(4-trifluoromethylphenyl)-pyrimidine ((N.5.8) CAS 180608-33-7); benzobicyclon (N.5.9), benzofenap (N.5.10), bicyclopyrone (N.5.11), clomazone (N.5.12), fenquintrione (N.5.13), isoxaflutole (N.5.14), mesotrione (N.5.15), pyrasulfotole (N.5.16), pyrazolynate (N.5.17), pyrazoxyfen (N.5.18), sulcotrione (N.5.19), tefuryltrione (N.5.20), tembotrione (N.5.21), tolpyralate (N.5.22), topramezone (N.5.23); aclonifen (N.5.24), amitrole (N.5.25), flumeturon (N.5.26);

N.6 EPSP synthase inhibitors: glyphosate (N.6.1), glyphosate-isopropylammonium (N.6.2), glyposate-potassium (N.6.3), glyphosate-trimesium (sulfosate) (N.6.4);

N.7 Glutamine synthase inhibitors: bilanaphos (bialaphos) (N.7.1), bilanaphos-sodium (N.7.2), glufosinate (N.7.3), glufosinate-P (N.7.4), glufosinate-ammonium (N.7.5);

N.8 DHP synthase inhibitors: asulam (N.8.1);

N.9 Mitosis inhibitors: benfluralin (N.9.1), butralin (N.9.2), dinitramine (N.9.3), ethalfluralin (N.9.4), fluchloralin (N.9.5), oryzalin (N.9.6), pendimethalin (N.9.7), prodiamine (N.9.8), trifluralin (N.9.9); amiprophos (N.9.10), amiprophos-methyl (N.9.11), butamiphos (N.9.12); chlorthal (N.9.13), chlorthal-dimethyl (N.9.14), dithiopyr (N.9.15), thiazopyr (N.9.16), propyzamide (N.9.17), tebutam (N.9.18); carbetamide (N.9.19), chlorpropham (N.9.20), flamprop (N.9.21), flamprop-isopropyl (N.9.22), flamprop-methyl (N.9.23), flamprop-M-isopropyl (N.9.24), flamprop-M-methyl (N.9.25), propham (N.9.26);

N.10 VLCFA inhibitors: acetochlor (N.10.1), alachlor (N.10.2), butachlor (N.10.3), dimethachlor (N.10.4), dimethenamid (N.10.5), dimethenamid-P (N.10.6), metazachlor (N.10.7), metolachlor (N.10.8), metolachlor-S(N.10.9), pethoxamid (N.10.10), pretilachlor (N.10.11), propachlor (N.10.12), propisochlor (N.10.13), thenylchlor (N.10.14), flufenacet (N.10.15), mefenacet (N.10.16), diphenamid (N.10.17), naproanilide (N.10.18), napropamide (N.10.19), napropamide-M (N.10.20), fentrazamide (N.10.21), anilofos (N.10.22), cafenstrole (N.10.23), fenoxasulfone (N.10.24), ipfencarbazone (N.10.25), piperophos (N.10.26), pyroxasulfone (N.10.27), isoxazoline compounds of the formulae II.1, II.2, II.3, II.4, II.5, II.6, II.7, II.8 and II.9

[Image Omitted]

N.11 Cellulose biosynthesis inhibitors: chlorthiamid (N.11.1), dichlobenil (N.11.2), flupoxam (N.11.3), indaziflam (N.11.4), isoxaben (N.11.5), triaziflam (N.11.6), 1-cyclohexyl-5-pentafluorphenyloxy-1 4-[1,2,4,6]thiatriazin-3-ylamine ((N.11.7) CAS 175899-01-1);

N.12 Decoupler herbicides: dinoseb (N.12.1), dinoterb (N.12.2), DNOC (N.12.3) and its salts;

N.13 Auxinic herbicides: 2,4-D (N.13.1) and its salts and esters, clacyfos (N.13.2), 2,4-DB (N.13.3) and its salts and esters, aminocyclopyrachlor (N.13.4) and its salts and esters, aminopyralid (N.13.5) and its salts such as aminopyralid-dimethylammonium (N.13.6), aminopyralid-tris(2-hydroxypropyl)ammonium (N.13.7) and its esters, benazolin (N.13.8), benazolin-ethyl (N.13.9), chloramben (N.13.10) and its salts and esters, clomeprop (N.13.11), clopyralid (N.13.12) and its salts and esters, dicamba (N.13.13) and its salts and esters, dichlorprop (N.13.14) and its salts and esters, dichlorprop-P (N.13.15) and its salts and esters, fluroxypyr (N.13.16), fluroxypyr-butometyl (N.1 3.17), fluroxypyr-meptyl (N.13.18), halauxifen (N.13.3) and its salts and esters (CAS 943832-60-8); MCPA (N.13.4) and its salts and esters, MCPA-thioethyl (N.13.19), MCPB (N.13.20) and its salts and esters, mecoprop (N.13.21) and its salts and esters, mecoprop-P (N.13.22) and its salts and esters, picloram (N.13.23) and its salts and esters, quinclorac (N.13.24), quinmerac (N.13.25), TBA (2,3,6) (N.13.26) and its salts and esters, triclopyr (N.13.27) and its salts and esters, 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid (N.13.28), benzyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylate ((N.13.29) CAS 1390661-72-9);

N.14 Auxin transport inhibitors: diflufenzopyr (N.14.1), diflufenzopyr-sodium (N.14.2), naptalam (N.14.3) and naptalam-sodium (N.14.4);

N.15 Other herbicides: bromobutide (N.15.1), chlorflurenol (N.15.2), chlorflurenol-methyl (N.15.3), cinmethylin (N.15.4), cumyluron (N.15.5), cyclopyrimorate ((N.15.6) CAS 499223-49-3) and its salts and esters, dalapon (N.15.7), dazomet (N.15.8), difenzoquat (N.15.9), difenzoquat-metilsulfate (N.15.10), dimethipin (N.15.11), DSMA (N.15.12), dymron (N.15.13), endothal (N.15.14) and its salts, etobenzanid (N.15.15), flurenol (N.15.16), flurenol-butyl (N.15.17), flurprimidol (N.15.18), fosamine (N.15.19), fosamine-ammonium (N.15.20), indanofan (N.15.21), maleic hydrazide (N.15.22), mefluidide (N.15.23), metam (N.15.24), methiozolin ((N.15.25) CAS 403640-27-7), methyl azide (N.15.26), methyl bromide (N.15.27), methyl-dymron (N.15.28), methyl iodide (N.15.29), MSMA (N.15.30), oleic acid (N.15.31), oxaziclomefone (N.15.32), pelargonic acid (N.15.33), pyributicarb (N.15.34), quinoclamine (N.15.35), tridiphane (N.15.36);

O) Insecticides from classes O.1 to O.29

O.1 Acetylcholine esterase (AChE) inhibitors: aldicarb (O.1.1), alanycarb (O.1.2), bendiocarb (O.1.3), benfuracarb (O.1.4), butocarboxim (O.1.5), butoxycarboxim (O.1.6), carbaryl (O.1.7), carbofuran (O.1.8), carbosulfan (O.1.9), ethiofencarb (O.1.10), fenobucarb (O.1.11), formetanate (O.1.12), furathiocarb (O.1.13), isoprocarb (O.1.14), methiocarb (O.1.15), methomyl (O.1.16), metolcarb (O.1.17), oxamyl (O.1.18), pirimicarb (O.1.19), propoxur (O.1.20), thiodicarb (O.1.21), thiofanox (O.1.22), trimethacarb (O.1.23), XMC (O.1.24), xylylcarb (O.1.25) and triazamate (O.1.26); acephate (O.1.27), azamethiphos (O.1.28), azinphos-ethyl (O.1.29), azinphosmethyl (O.1.30), cadusafos (O.1.31), chlorethoxyfos (O.1.32), chlorfenvinphos (O.1.33), chlormephos (O.1.34), chlorpyrifos (O.1.35), chlorpyrifos-methyl (O.1.36), coumaphos (O.1.37), cyanophos (O.1.38), demeton-S-methyl (O.1.39), diazinon (O.1.40), dichlorvos/DDVP (O.1.41), dicrotophos (O.1.42), dimethoate (O.1.43), dimethylvinphos (O.1.44), disulfoton (O.1.45), EPN (O.1.46), ethion (O.1.47), ethoprophos (O.1.48), famphur (O.1.49), fenamiphos (O.1.50), fenitrothion (O.1.51), fenthion (O.1.52), fosthiazate (O.1.53), heptenophos (O.1.54), imicyafos (O.1.55), isofenphos (O.1.56), isopropyl O-(methoxyaminothio-phosphoryl) salicylate (O.1.57), isoxathion (O.1.58), malathion (O.1.59), mecarbam (O.1.60), methamidophos (O.1.61), methidathion (O.1.62), mevinphos (O.1.63), monocrotophos (O.1.64), naled (O.1.65), omethoate (O.1.66), oxydemeton-methyl (O.1.67), parathion (O.1.68), parathion-methyl (O.1.69), phenthoate (O.1.70), phorate (O.1.71), phosalone (O.1.72), phosmet (O.1.73), phosphamidon (O.1.74), phoxim (O.1.75), pirimiphos-methyl (O.1.76), profenofos (O.1.77), propetamphos (O.1.78), prothiofos (O.1.79), pyraclofos (O.1.80), pyridaphenthion (O.1.81), quinalphos (O.1.82), sulfotep (O.1.83), tebupirimfos (O.1.84), temephos (O.1.85), terbufos (O.1.86), tetrachlorvinphos (O.1.87), thiometon (O.1.88), triazophos (O.1.89), trichlorfon (O.1.90), vamidothion (O.1.91);

O.2 GABA-gated chloride channel antagonists: endosulfan (O.2.1), chlordane (O.2.2); ethiprole (O.2.3), fipronil (O.2.4), flufiprole (O.2.5), pyrafluprole (O.2.6), pyriprole (O.2.7);

O.3 Sodium channel modulators: acrinathrin (O.3.1), allethrin (O.3.2), d-cis-trans allethrin (O.3.3), d-trans allethrin (O.3.4), bifenthrin (O.3.5), bioallethrin (O.3.6), bioallethrin S-cylclopentenyl (O.3.7), bioresmethrin (O.3.8), cycloprothrin (O.3.9), cyfluthrin (O.3.10), beta-cyfluthrin (O.3.11), cyhalothrin (O.3.12), lambda-cyhalothrin (O.3.13), gamma-cyhalothrin (O.3.14), cypermethrin (O.3.15), alpha-cypermethrin (O.3.16), beta-cypermethrin (O.3.17), theta-cypermethrin (O.3.18), zeta-cypermethrin (O.3.19), cyphenothrin (O.3.20), deltamethrin (O.3.21), empenthrin (O.3.22), esfenvalerate (O.3.23), etofenprox (O.3.24), fenpropathrin (O.3.25), fenvalerate (O.3.26), flucythrinate (O.3.27), flumethrin (O.3.28), tau-fluvalinate (O.3.29), halfenprox (O.3.30), heptafluthrin (O.3.31), imiprothrin (O.3.32), meperfluthrin (O.3.33), metofluthrin (O.3.34), momfluorothrin (O.3.35), permethrin (O.3.36), phenothrin (O.3.37), prallethrin (O.3.38), profluthrin (O.3.39), pyrethrin (pyrethrum) (O.3.40), resmethrin (O.3.41), silafluofen (O.3.42), tefluthrin (O.3.43), tetramethylfluthrin (O.3.44), tetramethrin (O.3.45), tralomethrin (O.3.46) and transfluthrin (O.3.47); DDT (O.3.48), methoxychlor (O.3.49);

O.4 Nicotinic acetylcholine receptor agonists (nAChR): acetamiprid (O.4.1), clothianidin (O.4.2), cycloxaprid (O.4.3), dinotefuran (O.4.4), imidacloprid (O.4.5), nitenpyram (O.4.6), thiacloprid (O.4.7), thiamethoxam (O.4.8); (2E)-1-[(6-chloropyridin-3-yl)methyl]-N′-nitro-2-pentylidene-hydrazinecarboximidamide (O.4.9); 1-[(6-chloropyridin-3-yl)methyl]-7-methyl-8-nitro-5-propoxy-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridine (O.4.10); nicotine (O.4.11);

O.5 Nicotinic acetylcholine receptor allosteric activators: spinosad (0.5.1), spinetoram (0.5.2);

O.6 Chloride channel activators: abamectin (O.6.1), emamectin benzoate (O.6.2), ivermectin (O.6.3), lepimectin (O.6.4), milbemectin (O.6.5);

O.7 Juvenile hormone mimics: hydroprene (O.7.1), kinoprene (O.7.2), methoprene (O.7.3); fenoxycarb (O.7.4), pyriproxyfen (O.7.5);

O.8 miscellaneous non-specific (multi-site) inhibitors: methyl bromide (O.8.1) and other alkyl halides; chloropicrin (O.8.2), sulfuryl fluoride (O.8.3), borax (O.8.4), tartar emetic (O.8.5);

O.9 Selective homopteran feeding blockers: pymetrozine (0.9.1), flonicamid (0.9.2);

O.10 Mite growth inhibitors: clofentezine (O.10.1), hexythiazox (O.10.2), diflovidazin (O.10.3); etoxazole (O.10.4);

O.11 Microbial disruptors of insect midgut membranes: the Bt crop proteins: CryAb, CryAc, Cry1Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, Cry34/35Ab1;

O.12 Inhibitors of mitochondrial ATP synthase: diafenthiuron (O.12.1); azocyclotin (O.12.2), cyhexatin (O.12.3), fenbutatin oxide (O.12.4), propargite (O.12.5), tetradifon (O.12.6);

O.13 Uncouplers of oxidative phosphorylation via disruption of the proton gradient: chlorfenapyr (O.13.1), DNOC (O.13.2), sulfluramid (O.13.3);

O.14 Nicotinic acetylcholine receptor (nAChR) channel blockers: bensultap (0.14.1), cartap hydrochloride (O.14.2), thiocyclam (O.14.3), thiosultap sodium (O.14.4);

O.15 Inhibitors of the chitin biosynthesis type 0: bistrifluron (O.15.1), chlorfluazuron (O.15.2), diflubenzuron (O.15.3), flucycloxuron (O.15.4), flufenoxuron (O.15.5), hexaflumuron (O.15.6), lufenuron (O.15.7), novaluron (O.15.8), noviflumuron (O.15.9), teflubenzuron (O.15.10), triflumuron (O.15.11);

O.16 Inhibitors of the chitin biosynthesis type 1: buprofezin (O.16.1);

O.17 Moulting disruptors: cyromazine (O.17.1);

O.18 Ecdyson receptor agonists: methoxyfenozide (O.18.1), tebufenozide (O.18.2), halofenozide (O.18.3), fufenozide (O.18.4), chromafenozide (O.18.5);

O.19 Octopamin receptor agonists: amitraz (O.19.1);

O.20 Mitochondrial complex III electron transport inhibitors: hydramethylnon (O.20.1), acequinocyl (O.20.2), fluacrypyrim (O.20.3);

O.21 Mitochondrial complex I electron transport inhibitors: fenazaquin (O.21.1), fenpyroximate (O.21.2), pyrimidifen (O.21.3), pyridaben (O.21.4), tebufenpyrad (O.21.5), tolfenpyrad (O.21.6); rotenone (O.21.7);

O.22 Voltage-dependent sodium channel blockers: indoxacarb (O.22.1), metaflumizone (O.22.2), 2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(difluoromethoxy)phenyl]-hydrazinecarboxamide (O.22.3), N-(3-chloro-2-methylphenyl)-2-[(4-chlorophenyl)-[4-[methyl(methylsulfonyl)amino]phenyl]methylene]-hydrazinecarboxamide (O.22.4);

O.23 Inhibitors of the of acetyl CoA carboxylase: spirodiclofen (O.23.1), spiromesifen (O.23.2), spirotetramat (O.23.3);

O.24 Mitochondrial complex IV electron transport inhibitors: aluminium phosphide (O.24.1), calcium phosphide (O.24.2), phosphine (O.24.3), zinc phosphide (O.24.4), cyanide (O.24.5);

O.25 Mitochondrial complex II electron transport inhibitors: cyenopyrafen (O.25.1), cyflumetofen (O.25.2);

O.26 Ryanodine receptor-modulators: flubendiamide (O.26.1), chlorantraniliprole (O.26.2), cyantraniliprole (O.26.3), cyclaniliprole (O.26.4), tetraniliprole (O.26.5); (R)-3-chloro-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}-N2-(1-methyl-2-methylsulfonylethyl)phthalamide (O.26.6), (S)-3-chloro-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}-N2-(1-methyl-2-methylsulfonylethyl)phthalamide (O.26.7), methyl-2-[3,5-dibromo-2-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)benzoyl]-1,2-dimethylhydrazinecarboxylate (O.26.8); N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)-carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide (O.26.9); N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide (O.26.10); N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide (O.26.11); N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide (O.26.12); N-[4,6-di-bromo-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(tri-fluoromethyl)pyrazole-3-carboxamide (O.26.13); N-[2-(5-amino-1,3,4-thiadiazol-2-yl)-4-chloro-6-methylphenyl]-3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide (O.26.14); 3-chloro-1-(3-chloro-2-pyridinyl)-N-[2,4-dichloro-6-[[(1-cyano-1-methylethyl)amino]carbonyl]phenyl]-1H-pyrazole-5-carboxamide (O.26.15); 3-bromo-N-[2,4-dichloro-6-(methylcarbamoyl)phenyl]-1-(3,5-dichloro-2-pyridyl)-1H-pyrazole-5-carboxamide (O.26.16); N-[4-chloro-2-[[(1,1-dimethylethyl)amino]carbonyl]-6-methylphenyl]-1-(3-chloro-2-pyridinyl)-3-(fluoromethoxy)-1H-pyrazole-5-carboxamide (O.26.17); cyhalodiamide (O.26.18);

O.27. insecticidal active compounds of unknown or uncertain mode of action: afidopyropen (O.27.1), afoxolaner (O.27.2), azadirachtin (O.27.3), amidoflumet (O.27.4), benzoximate (O.27.5), bifenazate (O.27.6), broflanilide (O.27.7), bromopropylate (O.27.8), chinomethionat (O.27.9), cryolite (O.27.10), dicloromezotiaz (O.27.11), dicofol (O.27.12), flufenerim (O.27.13), flometoquin (O.27.14), fluensulfone (O.27.15), fluhexafon (O.27.16), fluopyram (O.27.17), flupyradifurone (O.27.18), fluralaner (O.27.19), metoxadiazone (O.27.20), piperonyl butoxide (O.27.21), pyflubumide (O.27.22), pyridalyl (O.27.23), pyrifluquinazon (O.27.24), sulfoxaflor (O.27.25), tioxazafen (O.27.26), triflumezopyrim (O.27.27), 11-(4-chloro-2,6-dimethylphenyl)-12-hydroxy-1,4-dioxa-9-azadispiro[4.2.4.2]-tetradec-11-en-10-one (O.27.28), 3-(4′-fluoro-2,4-dimethylbiphenyl-3-yl)-4-hydroxy-8-oxa-1-azaspiro[4.5]dec-3-en-2-one (O.27.28), 1-[2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-amine (O.27.29), (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide (O.27.31); (E/Z)—N-[1-[(6-chloro-5-fluoro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide (O.27.32); (E/Z)-2,2,2-trifluoro-N-[1-[(6-fluoro-3-pyridyl)methyl]-2-pyridylidene]acetamide (O.27.33); (E/Z)—N-[1-[(6-bromo-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide (O.27.34); (E/Z)—N-[1-[1-(6-chloro-3-pyridyl)ethyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide (O.27.35); (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2-difluoro-acetamide (O.27.36); (E/Z)-2-chloro-N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2-difluoro-acetamide (O.27.37); (E/Z)—N-[1-[(2-chloropyrimidin-5-yl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide (O.27.38); (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,3,3,3-pentafluoro-propanamide (O.27.39); N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-thioacetamide (O.27.40); N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-N′-isopropyl-acetamidine (O.27.41); fluazaindolizine (O.27.42); 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]-2-methyl-N-(1-oxothietan-3-yl)benzamide (O.27.43); fluxamet-amide (O.27.44); 5-[3-[2,6-dichloro-4-(3,3-dichloroallyloxy)phenoxy]propoxy]-1H-pyrazole (O.27.45); 3-(benzoylmethylamino)-N-[2-bromo-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]-6-(trifluoromethyl)phenyl]-2-fluoro-benzamide (O.27.46); 3-(benzoylmethylamino)-2-fluoro-N-[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]-benzamide (O.27.47); N-[3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-N-methyl-benzamide (O.27.48); N-[3-[[[2-bromo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]-2-fluorophenyl]-4-fluoro-N-methyl-benzamide (O.27.49); 4-fluoro-N-[2-fluoro-3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoro-methyl)phenyl]amino]carbonyl]phenyl]-N-methyl-benzamide (O.27.50); 3-fluoro-N-[2-fluoro-3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6(trifluoromethyl)phenyl]amino]-carbonyl]phenyl]-N-methyl-benzamide (O.27.51); 2-chloro-N-[3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-3-pyridinecarboxamide (O.27.52); 4-cyano-N-[2-cyano-5-[[2,6-dibromo-4-[1,2,2,3,3,3-hexafluoro-1-(trifluorometh-yl)propyl]phenyl]carbamoyl]phenyl]-2-methyl-benzamide (O.27.53); 4-cyano-3-[(4-cyano-2-methyl-benzoyl)amino]-N-[2,6-dichloro-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)-propyl]phenyl]-2-fluoro-benzamide (O.27.54); N-[5-[[2-chloro-6-cyano-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide (O.27.55); N-[5-[[2-bromo-6-chloro-4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide (O.27.56); N-[5-[[2-bromo-6-chloro-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)-propyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide (O.27.57); 4-cyano-N-[2-cyano-5-[[2,6-dichloro-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]-carbamoyl]phenyl]-2-methyl-benzamide (O.27.58); 4-cyano-N-[2-cyano-5-[[2,6-dichloro-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]carbamoyl]phenyl]-2-methyl-benzamide (O.27.59); N-[5-[[2-bromo-6-chloro-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide (O.27.60); 2-(1,3-dioxan-2-yl)-6-[2-(3-pyridinyl)-5-thiazolyl]-pyridine; 2-[6-[2-(5-fluoro-3-pyridinyl)-5-thiazolyl]-2-pyridinyl]-pyrimidine (O.27.61); 2-[6-[2-(3-pyridinyl)-5-thiazolyl]-2-pyridinyl]-pyrimidine (O.27.62); N-methylsulfonyl-6-[2-(3-pyridyl)thiazol-5-yl]pyridine-2-carboxamide (O.27.63); N-methylsulfonyl-6-[2-(3-pyridyl)thiazol-5-yl]pyridine-2-carboxamide (O.27.64); N-ethyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide (O.27.65); N-methyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide (O.27.66); N,2-dimethyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide (O.27.67); N-ethyl-2-methyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide (O.27.68); N-[4-chloro-2-(3-pyridyl)thiazol-5-yl]-N-ethyl-2-methyl-3-methylthio-propanamide (O.2769); N-[4-chloro-2-(3-pyridyl)thiazol-5-yl]-N,2-dimethyl-3-methylthio-propanamide (O.27.70); N-[4-chloro-2-(3-pyridyl)thiazol-5-yl]-N-methyl-3-methylthio-propanamide (O.27.71); N-[4-chloro-2-(3-pyridyl)thiazol-5-yl]-N-ethyl-3-methylthio-propanamide (O.27.72); 1-[(6-chloro-3-pyri-dinyl)methyl]-1,2,3,5,6,7-hexahydro-5-methoxy-7-methyl-8-nitro-imidazo[1,2-a]pyridine (O.27.73); 1-[(6-chloropyridin-3-yl)methyl]-7-methyl-8-nitro-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridin-5-ol (O.27.74); 1-isopropyl-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide (O.27.75); 1-(1,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide (O.27.76); N,5-dimethyl-N-pyridazin-4-yl-1-(2,2,2-trifluoro-1-methyl-ethyl)pyrazole-4-carboxamide (O.27.77); 1-[1-(1-cyanocyclopropyl)ethyl]-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide (O.27.78); N-ethyl-1-(2-fluoro-1-methyl-propyl)-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide (O.27.79); 1-(1,2-dimethylpropyl)-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide (O.27.80); 1-[1-(1-cyanocyclopropyl)ethyl]-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide (O.27.81); N-methyl-1-(2-fluoro-1-methyl-propyl]-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide (O.27.82); 1-(4,4-difluorocyclohexyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide (O.27.83); 1-(4,4-difluorocyclohexyl)-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide (O.27.84), N-(1-methylethyl)-2-(3-pyridinyl)-2H-indazole-4-carboxamide (O.27.85); N-cyclopropyl-2-(3-pyridinyl)-2H-indazole-4-carboxamide (O.27.86); N-cyclohexyl-2-(3-pyridinyl)-2H-indazole-4-carboxamide (O.27.87); 2-(3-pyridinyl)-N-(2,2,2-trifluoroethyl)-2H-indazole-4-carboxamide (O.27.88); 2-(3-pyridinyl)-N-[(tetrahydro-2-furanyl)methyl]-2H-indazole-5-carboxamide (O.27.89); methyl 2-[[2-(3-pyridinyl)-2H-indazol-5-yl]carbonyl]hydrazinecarboxylate (O.27.90); N-[(2,2-difluorocyclopropyl)methyl]-2-(3-pyridinyl)-2H-indazole-5-carboxamide (O.27.91); N-(2,2-difluoropropyl)-2-(3-pyridinyl)-2H-indazole-5-carboxamide (O.27.92); 2-(3-pyridinyl)-N-(2-pyrimidinylmethyl)-2H-indazole-5-carboxamide (O.27.93); N-[(5-methyl-2-pyrazinyl)methyl]-2-(3-pyridinyl)-2H-indazole-5-carboxamide (O.27.94), N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropylsulfanyl)-propanamide (O.27.95); N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropylsulfinyl)propanamide (O.27.96); N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-3-[(2,2-di-fluorocyclopropyl)methylsulfanyl]-N-ethyl-propanamide (O.27.97); N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-3-[(2,2-difluorocyclopropyl)methylsulfinyl]-N-ethyl-propanamide (O.27.98); sarolaner (O.27.99), lotilaner (O.27.100).

The active substances referred to as component 2, their preparation and their activity e.g. against harmful fungi is known (cf.: http://www.alanwood.net/pesticides/); these substances are commercially available. The compounds described by IUPAC nomenclature, their preparation and their pesticidal activity are also known (cf. Can. J. Plant Sci. 48(6), 587-94, 1968; EP-A 141 317; EP-A 152 031; EP-A 226 917; EP-A 243 970; EP-A 256 503; EP-A 428 941; EP-A 532 022; EP-A 1 028 125; EP-A 1 035 122; EP-A 1 201 648; EP-A 1 122 244, JP 2002316902; DE 19650197; DE 10021412; DE 102005009458; U.S. Pat. No. 3,296,272; U.S. Pat. No. 3,325,503; WO 98/46608; WO 99/14187; WO 99/24413; WO 99/27783; WO 00/29404; WO 00/46148; WO 00/65913; WO 01/54501; WO 01/56358; WO 02/22583; WO 02/40431; WO 03/10149; WO 03/11853; WO 03/14103; WO 03/16286; WO 03/53145; WO 03/61388; WO 03/66609; WO 03/74491; WO 04/49804; WO 04/83193; WO 05/120234; WO 05/123689; WO 05/123690; WO 05/63721; WO 05/87772; WO 05/87773; WO 06/15866; WO 06/87325; WO 06/87343; WO 07/82098; WO 07/90624, WO 10/139271, WO 11/028657, WO 12/168188, WO 07/006670, WO 11/77514; WO 13/047749, WO 10/069882, WO 13/047441, WO 03/16303, WO 09/90181, WO 13/007767, WO 13/010862, WO 13/127704, WO 13/024009, WO 13/24010, WO 13/047441, WO 13/162072, WO 13/092224, WO 11/135833, CN 1907024, CN 1456054, CN 103387541, CN 1309897, WO 12/84812, CN 1907024, WO 09094442, WO 14/60177, WO 13/116251, WO 08/013622, WO 15/65922, WO 94/01546, EP 2865265, WO 07/129454, WO 12/165511, WO 11/081174, WO 13/47441).

The present invention furthermore relates to agrochemical compositions comprising a mixture of at least one compound I (component 1) and at least one further active substance useful for plant protection, e.g. selected from the groups A) to O) (component 2), in particular one further fungicide, e.g. one or more fungicide from the groups A) to K), as described above, and if desired one suitable solvent or solid carrier. Those mixtures are of particular interest, since many of them at the same application rate show higher efficiencies against harmful fungi. Furthermore, combating harmful fungi with a mixture of compounds I and at least one fungicide from groups A) to K), as described above, is more efficient than combating those fungi with individual compounds I or individual fungicides from groups A) to K).

By applying compounds I together with at least one active substance from groups A) to O) a synergistic effect can be obtained, i.e. more then simple addition of the individual effects is obtained (synergistic mixtures).

This can be obtained by applying the compounds I and at least one further active substance simultaneously, either jointly (e.g. as tank-mix) or seperately, or in succession, wherein the time interval between the individual applications is selected to ensure that the active substance applied first still occurs at the site of action in a sufficient amount at the time of application of the further active substance(s). The order of application is not essential for working of the present invention.

When applying compound I and a pesticide II sequentially the time between both applications may vary e.g. between 2 hours to 7 days. Also a broader range is possible ranging from 0.25 hour to 30 days, preferably from 0.5 hour to 14 days, particularly from 1 hour to 7 days or from 1.5 hours to 5 days, even more preferred from 2 hours to 1 day.

In the binary mixtures and compositions according to the invention the weight ratio of the component 1) and the component 2) generally depends from the properties of the active components used, usually it is in the range of from 1:10,000 to 10,000:1, often it is in the range of from 1:100 to 100:1, regularly in the range of from 1:50 to 50:1, preferably in the range of from 1:20 to 20:1, more preferably in the range of from 1:10 to 10:1, even more preferably in the range of from 1:4 to 4:1 and in particular in the range of from 1:2 to 2:1.

According to further embodiments of the binary mixtures and compositions, the weight ratio of the component 1) and the component 2) usually is in the range of from 1000:1 to 1:1, often in the range of from 100:1 to 1:1, regularly in the range of from 50:1 to 1:1, preferably in the range of from 20:1 to 1:1, more preferably in the range of from 10:1 to 1:1, even more preferably in the range of from 4:1 to 1:1 and in particular in the range of from 2:1 to 1:1.

According to a further embodiments of the binary mixtures and compositions, the weight ratio of the component 1) and the component 2) usually is in the range of from 1:1 to 1:1000, often in the range of from 1:1 to 1:100, regularly in the range of from 1:1 to 1:50, preferably in the range of from 1:1 to 1:20, more preferably in the range of from 1:1 to 1:10, even more preferably in the range of from 1:1 to 1:4 and in particular in the range of from 1:1 to 1:2.

In the ternary mixtures, i.e. compositions according to the invention comprising the component 1) and component 2) and a compound III (component 3), the weight ratio of component 1) and component 2) depends from the properties of the active substances used, usually it is in the range of from 1:100 to 100:1, regularly in the range of from 1:50 to 50:1, preferably in the range of from 1:20 to 20:1, more preferably in the range of from 1:10 to 10:1 and in particular in the range of from 1:4 to 4:1, and the weight ratio of component 1) and component 3) usually it is in the range of from 1:100 to 100:1, regularly in the range of from 1:50 to 50:1, preferably in the range of from 1:20 to 20:1, more preferably in the range of from 1:10 to 10:1 and in particular in the range of from 1:4 to 4:1.

Any further active components are, if desired, added in a ratio of from 20:1 to 1:20 to the component 1).

These ratios are also suitable for inventive mixtures applied by seed treatment.

Preference is also given to mixtures comprising as component 2) at least one active substance selected from inhibitors of complex III at Q_osite in group A), more preferably selected from compounds (A.1.1), (A.1.4), (A.1.8), (A.1.9), (A.1.10), (A.1.12), (A.1.13), (A.1.14), (A.1.17), (A.1.21), (A.1.24), (A.1.25), (A.1.26), (A.1.27), (A.1.30), (A.1.31), (A.1.32), (A.1.34) and (A.1.35); particularly selected from (A.1.1), (A.1.4), (A.1.8), (A.1.9), (A.1.13), (A.1.14), (A.1.17), (A.1.24), (A.1.25), (A.1.26), (A.1.27), (A.1.30), (A.1.31), (A.1.32), (A.1.34) and (A.1.35).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from inhibitors of complex III at Qi site in group A), more preferably selected from compounds (A.2.1), (A.2.3) and (A.2.4); particularly selected from (A.2.3) and (A.2.4).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from inhibitors of complex II in group A), more preferably selected from compounds (A.3.2), (A.3.3), (A.3.4), (A.3.7), (A.3.9), (A.3.11), (A.3.12), (A.3.15), (A.3.16), (A.3.17), (A.3.18), (A.3.19), (A.3.20), (A.3.21), (A.3.22), (A.3.23), (A.3.24), (A.3.25), (A.3.27), (A.3.28), (A.3.29), (A.3.31), (A.3.32), (A.3.33), (A.3.34), (A.3.35), (A.3.36), (A.3.37), (A.3.38) and (A.3.39); particularly selected from (A.3.2), (A.3.3), (A.3.4), (A.3.7), (A.3.9), (A.3.12), (A.3.15), (A.3.17), (A.3.19), (A.3.22), (A.3.23), (A.3.24), (A.3.25), (A.3.27), (A.3.29), (A.3.31), (A.3.32), (A.3.33), (A.3.34), (A.3.35), (A.3.36), (A.3.37), (A.3.38) and (A.3.39).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from other respiration inhibitors in group A), more preferably selected from compounds (A.4.5) and (A.4.11); in particular (A.4.11).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from C14 demethylase inhibitors in group B), more preferably selected from compounds (B.1.4), (B.1.5), (B.1.8), (B.1.10), (B.1.11), (B.1.12), (B.1.13), (B.1.17), (B.1.18), (B.1.21), (B.1.22), (B.1.23), (B.1.25), (B.1.26), (B.1.29), (B.1.34), (B.1.37), (B.1.38), (B.1.43) and (B.1.46); particularly selected from (B.1.5), (B.1.8), (B.1.10), (B.1.17), (B.1.22), (B.1.23), (B.1.25), (B.1.33), (B.1.34), (B.1.37), (B.138), (B.1.43) and (B.1.46).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from Delta14-reductase inhibitors in group B), more preferably selected from compounds (B.2.4), (B.2.5), (B.2.6) and (B.2.8); in particular (B.2.4).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from phenylamides and acyl amino acid fungicides in group C), more preferably selected from compounds (C.1.1), (C.1.2), (C.1.4) and (C.1.5); particularly selected from (C.1.1) and (C.1.4).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from other nucleic acid synthesis inhibitors in group C), more preferably selected from compounds (C.2.6), (C.2.7) and (C.2.8).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from group D), more preferably selected from compounds (D.1.1), (D.1.2), (D.1.5), (D.2.4) and (D.2.6); particularly selected from (D.1.2), (D.1.5) and (D.2.6).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from group E), more preferably selected from compounds (E.1.1), (E.1.3), (E.2.2) and (E.2.3); in particular (E.1.3).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from group F), more preferably selected from compounds (F.1.2), (F.1.4) and (F.1.5).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from group G), more preferably selected from compounds (G.3.1), (G.3.3), (G.3.6), (G.5.1), (G.5.2), (G.5.3), (G.5.4), (G.5.5), G.5.6), G.5.7), (G.5.8), (G.5.9), (G.5.10) and (G.5.11); particularly selected from (G.3.1), (G.5.1), (G.5.2) and (G.5.3).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from group H), more preferably selected from compounds (H.2.2), (H.2.3), (H.2.5), (H.2.7), (H.2.8), (H.3.2), (H.3.4), (H.3.5), (H.4.9) and (H.4.10); particularly selected from (H.2.2), (H.2.5), (H.3.2), (H.4.9) and (H.4.10).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from group I), more preferably selected from compounds (I.2.2) and (I.2.5).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from group J), more preferably selected from compounds (J.1.2), (J.1.5) and (J.1.8); in particular (J.1.5).

Preference is also given to mixtures comprising as component 2) at least one active substance selected from group K), more preferably selected from compounds (K.1.41), (K.1.42), (K.1.44), (K.1.45), (K.1.47) and (K.1.49); particularly selected from (K.1.41), (K.1.44), (K.1.45), (K.1.47) and (K.1.49).

Accordingly, the present invention furthermore relates to mixtures comprising one compound of the formula I (component 1) and one pesticide II (component 2), wherein pesticide II is selected from the column “Co. 2” of the lines B-1 to B-727 of Table B.

A further embodiment relates to the mixtures B-1 to B-727 listed in Table B, where a row of Table B corresponds in each case to a fungicidal mixture comprising as active components one of the in the present specification individualized compounds of formula I, i.e. compounds I.A.1-1 to I.A.I-2102, I.B.I-1 to I.B.I-2102, I.C.I-1 to I.C.I-2102 and I.D.I-1 to I.D.I-2102, as defined in tables 1 to 4 above (component 1 in column “Co.1”) and the respective pesticide II from groups A) to O) (component 2) stated in the row in question.

Another embodiment relates to the mixtures B-1 to B-727 listed in Table B, where a row of Table B corresponds in each case to a fungicidal mixture comprising as active components one of the compounds I.A-1 to I.A-37, I.B-1 to I.B-27, I.D-1 and I.D-2 as defined below in table I (component 1 in column “Co.1”) and the respective pesticide II from groups A) to O) (component 2) stated in the row in question.

Preferably, the compositions described in Table B comprise the active components in synergistically effective amounts.

TABLE B

Mixtures comprising as active components one indiviualized compound

of the fomula I (in column Co. 1), in particular compounds I.A.I-1

to I.A.I-2102, I.B.I-1 to I.B.I-2102, I.C.I-1 to I.C.I-2102 and

I.D.I-1 to I.D.I-2102 as defined in tables 1 to 4, or more particularly

compounds I.A-1 to I.A-37, I.B-1 to I.B-27, I.D-1 and I.D-2, as

defined below tables I, II and III and as component 2) (in column

Co. 2) one pesticide from groups A) to O) [which is coded e.g.

as (A.1.1) for azoxystrobin as defined above].

Mixt.
Co. 1
Co. 2

B-1
(I)
(A.1.1)

B-2
(I)
(A.1.2)

B-3
(I)
(A.1.3)

B-4
(I)
(A.1.4)

B-5
(I)
(A.1.5)

B-6
(I)
(A.1.6)

B-7
(I)
(A.1.7)

B-8
(I)
(A.1.8)

B-9
(I)
(A.1.9)

B-10
(I)
(A.1.10)

B-11
(I)
(A.1.11)

B-12
(I)
(A.1.12)

B-13
(I)
(A.1.13)

B-14
(I)
(A.1.14)

B-15
(I)
(A.1.15)

B-16
(I)
(A.1.16)

B-17
(I)
(A.1.17)

B-18
(I)
(A.1.18)

B-19
(I)
(A.1.19)

B-20
(I)
(A.1.20)

B-21
(I)
(A.1.21)

B-22
(I)
(A.1.22)

B-23
(I)
(A.1.23)

B-24
(I)
(A.1.24)

B-25
(I)
(A.1.25)

B-26
(I)
(A.1.26)

B-27
(I)
(A.1.27)

B-28
(I)
(A.1.30)

B-29
(I)
(A.1.31)

B-30
(I)
(A.1.32)

B-31
(I)
(A.2.1)

B-32
(I)
(A.2.2)

B-33
(I)
(A.2.3)

B-34
(I)
(A.2.4)

B-35
(I)
(A.2.6)

B-36
(I)
(A.2.7)

B-37
(I)
(A.2.8)

B-38
(I)
(A.3.1)

B-39
(I)
(A.3.2)

B-40
(I)
(A.3.3)

B-41
(I)