With the present invention, the Perfusionist will enter all surgeon instructions into a mobile pre-incision briefing tool. The instructions will be converted to an advanced clinical guidance prescription in real time. The surgeon will have full visibility into compliance with the advanced clinical guidance prescription in real time while case in process. Surgeon will also be able to view compliance summary at the cases end in any format, including mobile.

Definitions and Abbreviations

- HCT: hematocrit (%)
- Hb: hemoglobin (g/dL)
- CPB: cardiopulmonary bypass
- T: temperature (° C.)
- VO₂=oxygen consumption (mL/min)
- VO₂i=oxygen consumption indexed (mL/min/m²)
- DO₂=oxygen delivery (mL/min)
- DO₂i=oxygen delivery indexed (mL/min/m²)
- O₂ER=oxygen extraction rate (%)
- VCO₂=carbon dioxide production (mL/min)
- VCO₂i=carbon dioxide production indexed (mL/min/m²)
- Ve=ventilation (L/min)
- eCO₂=exhaled carbon dioxide (mmHg)
- AT=anaerobic threshold
- LAC=lactates
- Qc=cardiac output (mL/min)
- IC=cardiac index (Qc/m²), (mL/min/m²)
- Qp=pump flow (mL/min)
- IP=pump flow indexed (Qp/m²), (mL/min/m²)
- CaO₂=arterial oxygen content (mL/dL)
- Cv O₂=venous oxygen content (mL/dL)
- PaO₂=arterial oxygen tension (mmHg)
- PvO₂=venous oxygen tension (mmHg)
- a=arterial
- v=venous
- Sat=Hb saturation (%)

The following equations are applied to implement the monitoring system according to the invention:

VO
2

=

Qc
×

(

CaO
2

-

Cv
⁢
O

2

)

⁢

in
⁢

a
⁢

normal
⁢

circulation

(
1
)

VO
2

=

Qp
×

(

Ca
⁢

O
2

-

Cv
⁢
O

2

)

⁢

during
⁢

CPB

(
2
)

D
⁢
O

2

=

Qc
×

CaO
2

⁢

in
⁢

a
⁢

normal
⁢

circulation

(
3
)

D
⁢
O

2

=

Qp
×

CaO
2

⁢

during
⁢

CPB

(
4
)

O
2

⁢
ER

=

VO
2

/

D
⁢
O

2

⁢

(
%
)

(
5
)

Hb
=

HCT
/
3

(
6
)

CaO
2

=

Hb
×
1.36
×

Sat
⁡
(
a