100 according to some embodiments of the invention. FIG. 3A shows a distal portion of the exemplary treatment probe 100. As illustrated, exemplary treatment probe 100 includes an output tip 102 coupled with a distal end of a handle 104 and a cord 106 configured to couple the handle 104 to a console (e.g., console 12 of FIG. 2). Handle 104 may be configured for manipulation by an operator and may include one or more buttons (not shown) for controlling the delivery of the treatment laser and/or illumination light from a console 12 to an eye 1 of a patient. FIG. 3B shows a close up view of the exemplary output tip 102. The output tip 102 of the treatment probe 100 has a contact surface 108 for coupling with a surface of the eye 1. In some embodiments, a portion of the contact surface 108 may be constructed out of a transparent material so as to allow a user to visually observe the underlying eye tissues coupled with the contact surface 108. The contact surface 108 may contain an opening 110a for a distal end of a fiber optic 112 and openings 110b for distal ends of light pipe(s) 114. In the illustrated embodiment, opening 110a may be equidistant from either side 117 of the contact surface 108. Further, openings 110b may be equally and laterally spaced on each side of opening 110a.

Accordingly, in some embodiments, the fiber optic 112 may terminate at the contact surface 108 and may be configured to deliver a treatment laser directly to eye tissues coupled therewith. While illustrated as including a single fiber optic 112, it should be understood that other embodiments may have a plurality of fiber optics 112 for delivering treatment laser energy to a plurality of locations.

Also as illustrated in FIG. 3B, light pipes 114 may also terminate at the contact surface 108 and may thus apply illumination directly to the treatment site in order to illuminate the edge of the ciliary process 7 below the sclera 2 so as to facilitate the alignment of the distal end of the treatment fiber 112. The illumination fibers may be adhered to the output tip 102 using biocompatible adhesives for example. In some embodiments, the distal ends of the light pipe(s) 114 may be polished flush with contact surface 108. In the exemplary embodiment 100, two openings 110b are provided for a two distal ends of one or more light pipes 114. Some embodiments may comprise a plurality of light pipes 114 that each have distal ends that terminate at a contact surface 108. Alternatively, in some embodiments, a single light pipe 114 may branch off toward the distal portion of the treatment probe 100 to a plurality of distal ends. While illustrated as including two openings 110b for light pipe 114, it should be understood that other embodiments may include a single opening 110b for a light pipe 114, or more than two openings 110b (e.g., three, four, five, or more openings) for several distal ends of light pipe(s) 114.

As discussed above, contact surface 108 may couple with a surface of the eye 1. In some embodiments, the contact surface 108 may be contoured to register against the eye 1 at the limbus 4. For example, in some embodiments, the contact surface 108 may be contoured to generally conform to the shape of the eye 1 at the limbus 4 when the axis of the treatment probe 100 is parallel to the visual/optic axis 10 of the eye 1. This may be closely approximated as a concave spherical segment of radius 12.5 mm to 12.7 mm, the spherical center being located about 6.7 mm to 6.9 mm below the opening for the fiber optic 112. A contact surface 108 with such a configuration may facilitate the alignment of the exemplary treatment probe 100 with the eye 1 as shown in FIG. 3C. FIG. 3C shows the exemplary treatment probe 100 positioned against an eye 1. When the contoured contact surface 108 is registered against the eye 1 at the limbus 4, the treatment probe 100 may be aligned so as to direct treatment laser energy substantially parallel to the eye's visual axis 10.

Contact surface 108 may further include side edges 117 that are aligned as ray segments from the optic axis 10 of the eye 1. Such a configuration may be used to define treatment spacing edges and/or aid in the visual alignment of the treatment probe 100 around the eye 1. As shown and described above, the opening 110a and the distal end of the fiber optic 112 may be equidistant from either side 117 of the contact surface 108. In some embodiments, this half width may be chosen to be roughly equal to a desired treatment side spacing. After a first site is treated, each successive site may be selected by aligning a side edge 117 of the probe contact surface 108 with the lesion created at the previous site. In its simplest form, one lateral edge 117 may be a treatment spacing edge; used in the above described manner, the distance between treatment sites may be equal to the distance between the treatment spacing edge and the distal end of the fiber optic 112. A side relief 116 may extend back from the treatment spacing edge so that the edge may be visible during use.

In some embodiments, contact surface 108 may include a placement edge 118 with a placement contour 120 extending away from the placement edge 118 to the body of the handle 104. The placement edge 118 may be shaped to conform to the limbus 4, circularly concave with a radius of about 5.5-6.0 mm and about 1.2 mm from opening 110a. Knowing the distance between placement edge 118 and opening 110a may facilitate a desired alignment of the distal end of the fiber optic 112 with the eye's ciliary body 7. In some embodiments, a visual indicator (e.g., a line or groove) may be provided along the placement contour 120 that may provide a visual indication to an operator of the lateral position of the opening 110a. As mentioned above, some embodiments may have an output tip 102 and/or a contact surface 108 constructed partially or entirely out of a transparent material such that a user can visualize an alignment between opening 110a/fiber 112 and the eye tissues.

FIG. 3D shows an cross-sectional view of exemplary treatment probe 100. In some embodiments, an eyelid lifting contour 122 may be provided. The eyelid lifting contour 122 may comprise a circular concavity in an upper surface of output tip 102. The circular concavity may have a radius about 25 mm and a center of curvature located about 31 mm above the axis of the treatment probe 100. The eyelid lifting contour 122 may be any generally concave or scoop shaped relief of roughly the same size. Placement contour 120 may extend axially from placement edge 118. Fiber optic 112 is shown within a bore 124 and may extend slightly out from the contact surface 108. The output tip of fiber optic 112 may be polished flat. When contact surface 108 is registered against the eye 1, the protruding distal end of fiber optic 112 may indent the surface of the eye 1 and may squeeze out extracellular water, thus improving the transmission efficiency of the laser beam. The protrusion of the distal end of the fiber optic 112 may be anywhere from about 0.5 mm to about 1.0 mm, e.g., 0.75 mm. Also shown in FIG. 3D is a sheathed fiber optic portion 126 within a wider bore 128.

FIGS. 4A-4C illustrate yet another exemplary treatment probe 200. FIG. 4A shows a distal portion of treatment probe 200. FIG. 4B shows a close up view of an output tip 202 of treatment probe 200. FIG. 4C shows an exemplary placement of treatment probe 200 against a surface (e.g., sclera 2) of the eye 1. Treatment probe 200 may include an output tip 202 coupled with a distal end of a handle 204, and a cord 206 configured to couple handle 204 with a console (e.g., console 12 of FIG. 2). Treatment probe 200 may further include an output tip 202 with a contact surface 208 geometry (e.g., side edges 217, placement edge 218, placement contour 220, etc.) similar to output tip 102 that allows output tip 202 to rest against the sclera 2 and contour to the limbus 4 of the eye 1, as described above. Treatment probe 200 may further include a treatment fiber 212 and opening 210a similar to treatment probe 100. Treatment probe 200 may include a clearance hole 210b bored through the output tip approximately 0.1 inch closer to the visual axis 10 from an axis defined by the treatment fiber 212, so that a light pipe 214 may pass there through. In some embodiments, the illumination fiber may be adhered to the interior of the light pipe 214 and may pass through the fiber jacket. Treatment probe 200 may further include a button 205 on handle 204. Button 205 may be configured to provide user control of the application of illumination light and/or treatment laser to the eye 1. As can be seen in FIG. 4C, light pipe 214 may deliver illumination light in a direction parallel to and offset from the optical axis 10 of the eye 1 to illuminate the edge of the ciliary process 7. The illumination light from light pipe 214 may apply illumination through the cornea 3 to the angle of anterior chamber 9 of the eye 1. Optionally, in some embodiments, light pipe 214 may be manually adjustable to allow the probe 200 to be reconfigured for varying eye geometry, and/or for varying illumination. In some embodiments, probe 200 may be configured to deliver illumination light parallel to and along the visual axis 10 of the eye 1 so as to illuminate the ciliary body 7.

FIG. 5A-5C illustrate yet another exemplary treatment probe 300. FIG. 5A shows a distal portion of treatment probe 300. FIG. 5B shows a close up view of an output tip 302 of treatment probe 300. FIG. 5C shows an exemplary placement of treatment probe 300 against a surface of the eye 1. Treatment probe 300 may include an output tip 302 coupled with a distal end of a handle 304, and a cord 306 configured to couple handle 304 with a console (e.g., console 12 of FIG. 2). Treatment probe 300 may further include an output tip 302 with a contact surface 308 geometry (e.g., side relief 316, side edges 317, placement edge 318, placement contour 320, etc.) similar to output tip 102 that allows output tip 302 to rest against the sclera 2 and contour to the limbus 4 of the eye 1, as described above. Treatment probe 300 may further include a treatment fiber 312 and opening 310a similar to treatment probe 100. The treatment probe 300 may include a light pipe 314 similar to treatment probe 200, however, a clearance hole 310b may comprise an axially elongate slot along output tip 302 that exposes a length of light pipe 314. The length of light pipe 314 exposed may range between 1-5 cm. The distal end of the illumination light pipe 314 may be manually adjustable such that the illumination light pipe is reconfigurable to deliver light at different angles relative to the eye and/or to different regions of the eye. Further, a reconfigurable distal end of an illumination light pipe 314 may be advantageously accommodate for anatomical variation between patients and allow the light pipe 314 to be kept away from contact the cornea. In some embodiments, the light pipe 314 may have a semi-rigid portion to allow it to flex if contact is made with the cornea. The semi-rigid portion may mitigate risk of inadvertent damage to the cornea due to accidental contact. An axially elongated clearance hole 310b may expose a length of light pipe 314 that may be retracted without contacting output tip 302. The distal end of the light pipe 314 may be configured with a compound bend so that the light pipe 314 projects light at 30-60° angle from the visual axis 10 of the eye 1. A treatment probe 300 that projects light at such an angle may provide for better illumination of the angle of anterior chamber 9 and thus better illumination of the edge of the ciliary process 7. An angle between 30-60° may direct light through the cornea 3 and directly at the angle of anterior chamber 9. Treatment probe 300 may also include one or more buttons 305 for providing user control of the application of illumination light and/or treatment laser to the tissues of the eye 1.

FIGS. 6A-6C illustrate yet another exemplary treatment probe 400. FIG. 6A shows a distal portion of treatment probe 400. FIG. 6B shows a close up view of an output tip 402 of treatment probe 400. FIG. 6C shows an exemplary placement of treatment probe 400 against a surface of the eye 1. Treatment probe 400 may include an output tip 402 coupled with a distal end of a handle 404, and a cord 406 configured to couple handle 404 with a console (e.g., console 12 of FIG. 2). Treatment probe 400 may further include an output tip 402 with a contact surface 408 geometry (e.g., side relief 416, side edges 417, placement edge 418, etc.) similar to output tip 102 that allows output tip 402 to rest against the sclera 2 and contour to the limbus 4 of the eye 1, as described above. Treatment probe 400 may further include a treatment fiber 412 and opening 410a similar to treatment probe 100. The distal ends of light pipe(s) 414 may terminate at the contact surface 408 at openings 410b. Openings 410b may be positioned distally from a distal end of treatment fiber 412 at opening 410